Gene name: SUP45
Reference locus (S288C): YBR143C
Gene biotype: protein_coding
Description: Polypeptide release factor (eRF1) in translation termination; mutant form acts as a recessive omnipotent suppressor; methylated by Mtq2p-Trm112p in ternary complex eRF1-eRF3-GTP; mutation of methylation site confers resistance to zymocin; has a role in cytokinesis through interaction with Mlc1p
Top 10 interactors (score): RLI1 (0.999); SUP35 (0.999); NAM7 (0.998); MTQ2 (0.996); RPS2 (0.993); TRM112 (0.993); HBS1 (0.982); TIF34 (0.976); PRT1 (0.976); RPL5 (0.974); ARX1 (0.973); GCD11 (0.973); ASC1 (0.966); UPF3 (0.964); DOM34 (0.963); RPA135 (0.962); RPG1 (0.96); NMD2 (0.951); SKI7 (0.945); PAB1 (0.944)
Homologues (species, bitscore): ETF1 (Homo sapiens, 619.0); Etf1 (Mus musculus, 619.0); etf1 (Danio rerio, 629.4); etf1 (Xenopus tropicalis, 615.9); eRF1 (Drosophila melanogaster, 608.6); etf-1 (Caenorhabditis elegans, 596.7); ERF1-2 (Arabidopsis thaliana, 597.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:513756-515069:- | gene-YBR143C_AKU4011 | rna-NM_001178491.3_AKU4011 | cds-NP_009701.3_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:504327-505640:- | gene-YBR143C_BG1 | rna-NM_001178491.3_BG1 | cds-NP_009701.3_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:515546-516859:- | gene-YBR143C_Bruggeman | rna-NM_001178491.3_Bruggeman | cds-NP_009701.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:410901-412214:- | gene-YBR143C_CAT1 | rna-NM_001178491.3_CAT1 | cds-NP_009701.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:505536-506849:- | gene-YBR143C_CBS1585 | rna-NM_001178491.3_CBS1585 | cds-NP_009701.3_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:513638-514951:- | gene-YBR143C_CBS436 | rna-NM_001178491.3_CBS436 | cds-NP_009701.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:603401-604714:- | gene-YBR143C_CBS6412 | rna-NM_001178491.3_CBS6412 | cds-NP_009701.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:511170-512483:- | gene-YBR143C_CBS6413 | rna-NM_001178491.3_CBS6413 | cds-NP_009701.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:524638-525951:- | gene-YBR143C_CENPK1137D | rna-NM_001178491.3_CENPK1137D | cds-NP_009701.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:639777-641090:- | gene-YBR143C_EthanolRed | rna-NM_001178491.3_EthanolRed | cds-NP_009701.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:529789-531102:- | gene-YBR143C_FaliES1 | rna-NM_001178491.3_FaliES1 | cds-NP_009701.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000444.1:53239-54552:- | gene-YBR143C_JAY291 | rna-NM_001178491.3_JAY291 | cds-NP_009701.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:518420-519733:- | gene-YBR143C_MUCL30387 | rna-NM_001178491.3_MUCL30387 | cds-NP_009701.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:517710-519023:- | gene-YBR143C_MUCL30388 | rna-NM_001178491.3_MUCL30388 | cds-NP_009701.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:503923-505236:- | gene-YBR143C_MUCL39482 | rna-NM_001178491.3_MUCL39482 | cds-NP_009701.3_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:513814-515127:- | gene-YBR143C_MUCL42920 | rna-NM_001178491.3_MUCL42920 | cds-NP_009701.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:530666-531979:- | gene-YBR143C_NCIM3186 | rna-NM_001178491.3_NCIM3186 | cds-NP_009701.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:506461-507774:- | gene-YBR143C_NCYC1407 | rna-NM_001178491.3_NCYC1407 | cds-NP_009701.3_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:519085-520398:- | gene-YBR143C_PE2H3 | rna-NM_001178491.3_PE2H3 | cds-NP_009701.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:516761-518074:- | gene-YBR143C_PE2H4 | rna-NM_001178491.3_PE2H4 | cds-NP_009701.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:530869-532182:- | gene-YBR143C_S288C | rna-NM_001178491.3_S288C | cds-NP_009701.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000032.1:52053-53366:- | gene-YBR143C_SA1 | rna-NM_001178491.3_SA1 | cds-NP_009701.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:528802-530115:- | gene-YBR143C_ThermosaccDry | rna-NM_001178491.3_ThermosaccDry | cds-NP_009701.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:510302-511615:- | gene-YBR143C_VR1 | rna-NM_001178491.3_VR1 | cds-NP_009701.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:503949-505262:- | gene-YBR143C_ZTW1 | rna-NM_001178491.3_ZTW1 | cds-NP_009701.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:541176-542489:- | gene-YBR143C_Sparadoxus | rna-NM_001178491.3_Sparadoxus | cds-NP_009701.3_Sparadoxus | 92.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |