SUB2 (YDL084W)


Gene profile

Gene name: SUB2
Reference locus (S288C): YDL084W
Gene biotype: protein_coding

Description: ATP-dependent RNA helicase SUB2; Component of the TREX complex required for nuclear mRNA export; member of the DEAD-box RNA helicase superfamily and is involved in early and late steps of spliceosome assembly; homolog of the human splicing factor hUAP56; relocalizes from nucleus to cytoplasm upon DNA replication stress

Top 10 interactors (score): THP2 (0.999); YRA1 (0.999); HPR1 (0.999); THO2 (0.999); MEX67 (0.996); MFT1 (0.994); MUD2 (0.987); PCF11 (0.986); PRP22 (0.974); GUA1 (0.971); TEX1 (0.967); RRP6 (0.967); LSM8 (0.965); IQG1 (0.962); SNU114 (0.961); HRB1 (0.959); BRR2 (0.958); STO1 (0.958); GBP2 (0.958); NAB2 (0.956)

Homologues (species, bitscore): DDX39B (Homo sapiens, 579.7); Ddx39b (Mus musculus, 578.9); bat1 (Danio rerio, 575.5); ddx39a (Xenopus tropicalis, 561.2); Hel25E (Drosophila melanogaster, 555.8); hel-1 (Caenorhabditis elegans, 546.6); UAP56a (Arabidopsis thaliana, 568.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:289850-291190:+ gene-YDL084W_AKU4011 rna-NM_001180143.1_AKU4011 cds-NP_010199.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:258758-260098:- gene-YDL084W_BG1 rna-NM_001180143.1_BG1 cds-NP_010199.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:307520-308860:+ gene-YDL084W_Bruggeman rna-NM_001180143.1_Bruggeman cds-NP_010199.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:304008-305348:+ gene-YDL084W_CAT1 rna-NM_001180143.1_CAT1 cds-NP_010199.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:288122-289462:+ gene-YDL084W_CBS1585 rna-NM_001180143.1_CBS1585 cds-NP_010199.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:304789-306129:+ gene-YDL084W_CBS436 rna-NM_001180143.1_CBS436 cds-NP_010199.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:286550-287890:+ gene-YDL084W_CBS6412 rna-NM_001180143.1_CBS6412 cds-NP_010199.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:306176-307516:+ gene-YDL084W_CBS6413 rna-NM_001180143.1_CBS6413 cds-NP_010199.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:304060-305400:+ gene-YDL084W_CENPK1137D rna-NM_001180143.1_CENPK1137D cds-NP_010199.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:300885-302225:+ gene-YDL084W_EthanolRed rna-NM_001180143.1_EthanolRed cds-NP_010199.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:306857-308197:+ gene-YDL084W_FaliES1 rna-NM_001180143.1_FaliES1 cds-NP_010199.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000010.1:76908-78248:+ gene-YDL084W_JAY291 rna-NM_001180143.1_JAY291 cds-NP_010199.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:305036-306376:+ gene-YDL084W_MUCL30387 rna-NM_001180143.1_MUCL30387 cds-NP_010199.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:296060-297400:+ gene-YDL084W_MUCL30388 rna-NM_001180143.1_MUCL30388 cds-NP_010199.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:289227-290567:+ gene-YDL084W_MUCL39482 rna-NM_001180143.1_MUCL39482 cds-NP_010199.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:211237-212577:+ gene-YDL084W_MUCL42920 rna-NM_001180143.1_MUCL42920 cds-NP_010199.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:305160-306500:+ gene-YDL084W_NCIM3186 rna-NM_001180143.1_NCIM3186 cds-NP_010199.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:289242-290582:+ gene-YDL084W_NCYC1407 rna-NM_001180143.1_NCYC1407 cds-NP_010199.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:296026-297366:+ gene-YDL084W_PE2H3 rna-NM_001180143.1_PE2H3 cds-NP_010199.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:296025-297365:+ gene-YDL084W_PE2H4 rna-NM_001180143.1_PE2H4 cds-NP_010199.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:305237-306577:+ gene-YDL084W_S288C rna-NM_001180143.1_S288C cds-NP_010199.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000010.1:128345-129685:- gene-YDL084W_SA1 rna-NM_001180143.1_SA1 cds-NP_010199.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:306368-307708:+ gene-YDL084W_ThermosaccDry rna-NM_001180143.1_ThermosaccDry cds-NP_010199.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:308444-309784:+ gene-YDL084W_VR1 rna-NM_001180143.1_VR1 cds-NP_010199.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:304282-305622:+ gene-YDL084W_ZTW1 rna-NM_001180143.1_ZTW1 cds-NP_010199.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:306380-307720:+ gene-YDL084W_Sparadoxus rna-NM_001180143.1_Sparadoxus cds-NP_010199.1_Sparadoxus 94.6 100.0 Verified 1 1 1 False True False False False

Additional files