Gene name: SUB1
Reference locus (S288C): YMR039C
Gene biotype: protein_coding
Description: Transcriptional regulator; facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in nonhomologous end-joining (NHEJ) of ds breaks in plasmid DNA, but not chromosomal DNA; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes; negatively regulates sporulation; protein abundance increases in response to DNA replication stress; functionally complemented by human SUB1 (PC4)
Top 10 interactors (score): SUA7 (0.995); SPT5 (0.96); RPO21 (0.91); LSM5 (0.896); FCP1 (0.889); SMX2 (0.868); RNA15 (0.843); SPT15 (0.835); RPB3 (0.814); SPT4 (0.759); YDR544C (0.748); DST1 (0.747); SUB2 (0.725); SSU72 (0.712); IMD2 (0.701); RPB7 (0.694); TFC4 (0.688); YML009W-B (0.671); TIM13 (0.67); PUF3 (0.669)
Homologues (species, bitscore): SUB1 (Homo sapiens, 69.7); Sub1 (Mus musculus, 71.6); sub1b (Danio rerio, 74.7); sub1 (Xenopus tropicalis, 73.2); KIWI (Arabidopsis thaliana, 56.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:398247-399125:- | gene-YMR039C_AKU4011 | rna-NM_001182536.1_AKU4011 | cds-NP_013753.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:143674-144552:+ | gene-YMR039C_BG1 | rna-NM_001182536.1_BG1 | cds-NP_013753.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:338182-339060:- | gene-YMR039C_Bruggeman | rna-NM_001182536.1_Bruggeman | cds-NP_013753.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:340697-341587:- | gene-YMR039C_CAT1 | rna-NM_001182536.1_CAT1 | cds-NP_013753.1_CAT1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:331189-332067:- | gene-YMR039C_CBS1585 | rna-NM_001182536.1_CBS1585 | cds-NP_013753.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:336726-337604:- | gene-YMR039C_CBS436 | rna-NM_001182536.1_CBS436 | cds-NP_013753.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:444590-445468:- | gene-YMR039C_CBS6412 | rna-NM_001182536.1_CBS6412 | cds-NP_013753.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:330444-331322:- | gene-YMR039C_CBS6413 | rna-NM_001182536.1_CBS6413 | cds-NP_013753.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:343366-344244:- | gene-YMR039C_CENPK1137D | rna-NM_001182536.1_CENPK1137D | cds-NP_013753.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:331020-331898:- | gene-YMR039C_EthanolRed | rna-NM_001182536.1_EthanolRed | cds-NP_013753.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:334202-335080:- | gene-YMR039C_FaliES1 | rna-NM_001182536.1_FaliES1 | cds-NP_013753.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:101869-102747:+ | gene-YMR039C_JAY291 | rna-NM_001182536.1_JAY291 | cds-NP_013753.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:336141-337019:- | gene-YMR039C_MUCL30387 | rna-NM_001182536.1_MUCL30387 | cds-NP_013753.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:340560-341426:- | gene-YMR039C_MUCL30388 | rna-NM_001182536.1_MUCL30388 | cds-NP_013753.1_MUCL30388 | 98.5 | 98.6 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:331471-332349:- | gene-YMR039C_MUCL39482 | rna-NM_001182536.1_MUCL39482 | cds-NP_013753.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:337285-338163:- | gene-YMR039C_MUCL42920 | rna-NM_001182536.1_MUCL42920 | cds-NP_013753.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:348598-349476:- | gene-YMR039C_NCIM3186 | rna-NM_001182536.1_NCIM3186 | cds-NP_013753.1_NCIM3186 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:331388-332266:- | gene-YMR039C_NCYC1407 | rna-NM_001182536.1_NCYC1407 | cds-NP_013753.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:337326-338204:- | gene-YMR039C_PE2H3 | rna-NM_001182536.1_PE2H3 | cds-NP_013753.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:343421-344299:- | gene-YMR039C_PE2H4 | rna-NM_001182536.1_PE2H4 | cds-NP_013753.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:348644-349522:- | gene-YMR039C_S288C | rna-NM_001182536.1_S288C | cds-NP_013753.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:188737-189615:+ | gene-YMR039C_SA1 | rna-NM_001182536.1_SA1 | cds-NP_013753.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:331271-332149:- | gene-YMR039C_ThermosaccDry | rna-NM_001182536.1_ThermosaccDry | cds-NP_013753.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:335970-336848:- | gene-YMR039C_VR1 | rna-NM_001182536.1_VR1 | cds-NP_013753.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:310279-311157:- | gene-YMR039C_ZTW1 | rna-NM_001182536.1_ZTW1 | cds-NP_013753.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:344197-345078:- | gene-YMR039C_Sparadoxus | rna-NM_001182536.1_Sparadoxus | cds-NP_013753.1_Sparadoxus | 91.2 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |