Gene name: SUA5
Reference locus (S288C): YGL169W
Gene biotype: protein_coding
Description: Threonylcarbamoyl-AMP synthase; Protein involved in threonylcarbamoyl adenosine biosynthesis; Sua5p and Qri7p are necessary and sufficient for RNA t6A modification in vitro; null mutant lacks N6-threonylcarbamoyl adenosine (t6A) modification in the anticodon loop of ANN-decoding tRNA; member of conserved YrdC/Sua5 family; binds single-stranded telomeric DNA and null mutant has abnormal telomere length
Top 10 interactors (score): QRI7 (0.996); KAE1 (0.982); CGI121 (0.939); BUD32 (0.924); TRM5 (0.918); DEG1 (0.871); MOD5 (0.854); PUS7 (0.81); TAD2 (0.804); MSW1 (0.802); TAD3 (0.78); MTQ2 (0.751); BOL2 (0.747); PCC1 (0.715); RPC11 (0.713); RRP8 (0.708); YLR118C (0.707); MST1 (0.705); NCS6 (0.702); GON7 (0.693)
Homologues (species, bitscore): YRDC (Homo sapiens, 61.2); Yrdc (Mus musculus, 60.8); yrdc (Danio rerio, 89.0); yrdc (Xenopus tropicalis, 72.0); CG33786 (Drosophila melanogaster, 70.9); AT5G60590 (Arabidopsis thaliana, 60.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:188631-189911:+ | gene-YGL169W_AKU4011 | rna-NM_001181034.1_AKU4011 | cds-NP_011346.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:220451-221731:- | gene-YGL169W_BG1 | rna-NM_001181034.1_BG1 | cds-NP_011346.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:190825-192105:+ | gene-YGL169W_Bruggeman | rna-NM_001181034.1_Bruggeman | cds-NP_011346.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:186695-187975:+ | gene-YGL169W_CAT1 | rna-NM_001181034.1_CAT1 | cds-NP_011346.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:191770-193050:+ | gene-YGL169W_CBS1585 | rna-NM_001181034.1_CBS1585 | cds-NP_011346.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:186685-187965:+ | gene-YGL169W_CBS436 | rna-NM_001181034.1_CBS436 | cds-NP_011346.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:178233-179513:+ | gene-YGL169W_CBS6412 | rna-NM_001181034.1_CBS6412 | cds-NP_011346.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:186082-187362:+ | gene-YGL169W_CBS6413 | rna-NM_001181034.1_CBS6413 | cds-NP_011346.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:186286-187566:+ | gene-YGL169W_CENPK1137D | rna-NM_001181034.1_CENPK1137D | cds-NP_011346.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:178438-179718:+ | gene-YGL169W_EthanolRed | rna-NM_001181034.1_EthanolRed | cds-NP_011346.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:179684-180964:+ | gene-YGL169W_FaliES1 | rna-NM_001181034.1_FaliES1 | cds-NP_011346.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000090.1:29915-31195:+ | gene-YGL169W_JAY291 | rna-NM_001181034.1_JAY291 | cds-NP_011346.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:188073-189353:+ | gene-YGL169W_MUCL30387 | rna-NM_001181034.1_MUCL30387 | cds-NP_011346.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:191163-192443:+ | gene-YGL169W_MUCL30388 | rna-NM_001181034.1_MUCL30388 | cds-NP_011346.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:188794-190074:+ | gene-YGL169W_MUCL39482 | rna-NM_001181034.1_MUCL39482 | cds-NP_011346.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:191380-192660:+ | gene-YGL169W_MUCL42920 | rna-NM_001181034.1_MUCL42920 | cds-NP_011346.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:186059-187339:+ | gene-YGL169W_NCIM3186 | rna-NM_001181034.1_NCIM3186 | cds-NP_011346.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:180258-181538:+ | gene-YGL169W_NCYC1407 | rna-NM_001181034.1_NCYC1407 | cds-NP_011346.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:182216-183496:+ | gene-YGL169W_PE2H3 | rna-NM_001181034.1_PE2H3 | cds-NP_011346.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:181767-183047:+ | gene-YGL169W_PE2H4 | rna-NM_001181034.1_PE2H4 | cds-NP_011346.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:186059-187339:+ | gene-YGL169W_S288C | rna-NM_001181034.1_S288C | cds-NP_011346.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000067.1:45877-47157:+ | gene-YGL169W_SA1 | rna-NM_001181034.1_SA1 | cds-NP_011346.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:179913-181193:+ | gene-YGL169W_ThermosaccDry | rna-NM_001181034.1_ThermosaccDry | cds-NP_011346.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:187121-188401:+ | gene-YGL169W_VR1 | rna-NM_001181034.1_VR1 | cds-NP_011346.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:178364-179644:+ | gene-YGL169W_ZTW1 | rna-NM_001181034.1_ZTW1 | cds-NP_011346.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:185234-186514:+ | gene-YGL169W_Sparadoxus | rna-NM_001181034.1_Sparadoxus | cds-NP_011346.1_Sparadoxus | 90.3 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |