STT4 (YLR305C)


Gene profile

Gene name: STT4
Reference locus (S288C): YLR305C
Gene biotype: protein_coding

Description: Phosphatidylinositol-4-kinase; functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization; Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily

Top 10 interactors (score): MSS4 (0.999); SAC1 (0.999); LSB6 (0.998); EFR3 (0.997); FAB1 (0.993); PIK1 (0.983); SCS2 (0.975); INP53 (0.974); PIS1 (0.974); INP52 (0.97); YPP1 (0.966); INP51 (0.957); PLC1 (0.956); VPS34 (0.949); TEP1 (0.945); SEC14 (0.943); YMR1 (0.938); SFK1 (0.936); OSH2 (0.9); SPO14 (0.878)

Homologues (species, bitscore): PI4KA (Homo sapiens, 516.9); Pi4ka (Mus musculus, 513.8); pi4kaa (Danio rerio, 498.8); pi4ka (Xenopus tropicalis, 513.5); Pi4KIIIalpha (Drosophila melanogaster, 484.2); Y75B8A.24 (Caenorhabditis elegans, 462.6); PI4KA1 (Arabidopsis thaliana, 395.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:686608-692310:- gene-YLR305C_AKU4011 rna-NM_001182193.1_AKU4011 cds-NP_013408.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000170.1:40314-46016:+ gene-YLR305C_BG1 rna-NM_001182193.1_BG1 cds-NP_013408.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:722438-728140:- gene-YLR305C_Bruggeman rna-NM_001182193.1_Bruggeman cds-NP_013408.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:720611-726313:- gene-YLR305C_CAT1 rna-NM_001182193.1_CAT1 cds-NP_013408.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:721534-727236:- gene-YLR305C_CBS1585 rna-NM_001182193.1_CBS1585 cds-NP_013408.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:706151-711853:- gene-YLR305C_CBS436 rna-NM_001182193.1_CBS436 cds-NP_013408.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:684174-689876:- gene-YLR305C_CBS6412 rna-NM_001182193.1_CBS6412 cds-NP_013408.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:722200-727902:- gene-YLR305C_CBS6413 rna-NM_001182193.1_CBS6413 cds-NP_013408.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:722775-728477:- gene-YLR305C_CENPK1137D rna-NM_001182193.1_CENPK1137D cds-NP_013408.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:679886-685588:- gene-YLR305C_EthanolRed rna-NM_001182193.1_EthanolRed cds-NP_013408.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:709086-714788:- gene-YLR305C_FaliES1 rna-NM_001182193.1_FaliES1 cds-NP_013408.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000296.1:53033-58735:+ gene-YLR305C_JAY291 rna-NM_001182193.1_JAY291 cds-NP_013408.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:721672-727374:- gene-YLR305C_MUCL30387 rna-NM_001182193.1_MUCL30387 cds-NP_013408.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:727255-732957:- gene-YLR305C_MUCL30388 rna-NM_001182193.1_MUCL30388 cds-NP_013408.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:722764-728466:- gene-YLR305C_MUCL39482 rna-NM_001182193.1_MUCL39482 cds-NP_013408.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:717921-723623:- gene-YLR305C_MUCL42920 rna-NM_001182193.1_MUCL42920 cds-NP_013408.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:738135-743837:- gene-YLR305C_NCIM3186 rna-NM_001182193.1_NCIM3186 cds-NP_013408.1_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:732106-737808:- gene-YLR305C_NCYC1407 rna-NM_001182193.1_NCYC1407 cds-NP_013408.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:719918-725620:- gene-YLR305C_PE2H3 rna-NM_001182193.1_PE2H3 cds-NP_013408.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:719662-725364:- gene-YLR305C_PE2H4 rna-NM_001182193.1_PE2H4 cds-NP_013408.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:738161-743863:- gene-YLR305C_S288C rna-NM_001182193.1_S288C cds-NP_013408.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000039.1:40440-46142:+ gene-YLR305C_SA1 rna-NM_001182193.1_SA1 cds-NP_013408.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:710980-716682:- gene-YLR305C_ThermosaccDry rna-NM_001182193.1_ThermosaccDry cds-NP_013408.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:723129-728831:- gene-YLR305C_VR1 rna-NM_001182193.1_VR1 cds-NP_013408.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:49407-55109:- gene-YLR305C_ZTW1 rna-NM_001182193.1_ZTW1 cds-NP_013408.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:697081-702783:- gene-YLR305C_Sparadoxus rna-NM_001182193.1_Sparadoxus cds-NP_013408.1_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files