Gene name: STP22
Reference locus (S288C): YCL008C
Gene biotype: protein_coding
Description: Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease; Component of the ESCRT-I complex; ESCRT-I is involved in ubiquitin-dependent sorting of proteins into the endosome; prevents polyubiquitination of the arrestin-related protein Rim8p, thereby directing its monoubiquitination by Rsp5p; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype;; Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily
Top 10 interactors (score): SNF7 (0.999); VPS36 (0.999); VPS20 (0.999); MVB12 (0.999); SNF8 (0.999); VPS27 (0.999); VPS25 (0.999); SRN2 (0.999); VPS28 (0.999); VPS24 (0.999); DID4 (0.998); RIM8 (0.996); UBI4 (0.994); HSE1 (0.994); RPS31 (0.992); BRO1 (0.985); VPS4 (0.977); DID2 (0.975); RIM20 (0.964); VPS60 (0.941)
Homologues (species, bitscore): TSG101 (Homo sapiens, 104.4); Tsg101 (Mus musculus, 99.0); tsg101b (Danio rerio, 90.9); tsg101 (Xenopus tropicalis, 53.5); TSG101 (Drosophila melanogaster, 80.1); tsg-101 (Caenorhabditis elegans, 55.1); ELC (Arabidopsis thaliana, 86.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:100415-101572:- | gene-YCL008C_AKU4011 | rna-NM_001178657.1_AKU4011 | cds-NP_009919.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000178.1:44463-45620:+ | gene-YCL008C_BG1 | rna-NM_001178657.1_BG1 | cds-NP_009919.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:94998-96155:- | gene-YCL008C_Bruggeman | rna-NM_001178657.1_Bruggeman | cds-NP_009919.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:100144-101301:- | gene-YCL008C_CAT1 | rna-NM_001178657.1_CAT1 | cds-NP_009919.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:101063-102220:- | gene-YCL008C_CBS1585 | rna-NM_001178657.1_CBS1585 | cds-NP_009919.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:105979-107136:- | gene-YCL008C_CBS436 | rna-NM_001178657.1_CBS436 | cds-NP_009919.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:88522-89679:- | gene-YCL008C_CBS6412 | rna-NM_001178657.1_CBS6412 | cds-NP_009919.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:100370-101527:- | gene-YCL008C_CBS6413 | rna-NM_001178657.1_CBS6413 | cds-NP_009919.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:105171-106328:- | gene-YCL008C_CENPK1137D | rna-NM_001178657.1_CENPK1137D | cds-NP_009919.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:98432-99589:- | gene-YCL008C_EthanolRed | rna-NM_001178657.1_EthanolRed | cds-NP_009919.3_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:100725-101882:- | gene-YCL008C_FaliES1 | rna-NM_001178657.1_FaliES1 | cds-NP_009919.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000126.1:14897-16054:- | gene-YCL008C_JAY291 | rna-NM_001178657.1_JAY291 | cds-NP_009919.3_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:93433-94590:- | gene-YCL008C_MUCL30387 | rna-NM_001178657.1_MUCL30387 | cds-NP_009919.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:92990-94147:- | gene-YCL008C_MUCL30388 | rna-NM_001178657.1_MUCL30388 | cds-NP_009919.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:101480-102637:- | gene-YCL008C_MUCL39482 | rna-NM_001178657.1_MUCL39482 | cds-NP_009919.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:96713-97870:- | gene-YCL008C_MUCL42920 | rna-NM_001178657.1_MUCL42920 | cds-NP_009919.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:105328-106485:- | gene-YCL008C_NCIM3186 | rna-NM_001178657.1_NCIM3186 | cds-NP_009919.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:101962-103119:- | gene-YCL008C_NCYC1407 | rna-NM_001178657.1_NCYC1407 | cds-NP_009919.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:106131-107288:- | gene-YCL008C_PE2H3 | rna-NM_001178657.1_PE2H3 | cds-NP_009919.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:106091-107248:- | gene-YCL008C_PE2H4 | rna-NM_001178657.1_PE2H4 | cds-NP_009919.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:105696-106853:- | gene-YCL008C_S288C | rna-NM_001178657.1_S288C | cds-NP_009919.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000073.1:44479-45636:+ | gene-YCL008C_SA1 | rna-NM_001178657.1_SA1 | cds-NP_009919.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:101298-102455:- | gene-YCL008C_ThermosaccDry | rna-NM_001178657.1_ThermosaccDry | cds-NP_009919.3_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:111938-113095:- | gene-YCL008C_VR1 | rna-NM_001178657.1_VR1 | cds-NP_009919.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:100236-101393:- | gene-YCL008C_ZTW1 | rna-NM_001178657.1_ZTW1 | cds-NP_009919.3_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:130475-131632:- | gene-YCL008C_Sparadoxus | rna-NM_001178657.1_Sparadoxus | cds-NP_009919.3_Sparadoxus | 90.0 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |