Gene name: STP1
Reference locus (S288C): YDR463W
Gene biotype: protein_coding
Description: Transcription factor; contains a N-terminal regulatory motif (RI) that acts as a cytoplasmic retention determinant and as an Asi dependent degron in the nucleus; undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing; STP1 has a paralog, STP2, that arose from the whole genome duplication
Top 10 interactors (score): SSY5 (0.975); SSY1 (0.946); PTR3 (0.932); ASI3 (0.883); DAL81 (0.873); ASI2 (0.816); ASI1 (0.815); STP2 (0.769); GRR1 (0.765); AGP1 (0.747); GAP1 (0.737); GLN3 (0.715); BAP2 (0.711); HAP2 (0.703); AVT5 (0.695); YCK1 (0.651); LEU3 (0.619); MET4 (0.616); BAP3 (0.614); UGA3 (0.559)
Homologues (species, bitscore): ZNF408 (Homo sapiens, 58.5); Ikzf4 (Mus musculus, 54.7); IKZF4 (Danio rerio, 57.4); ikzf4 (Xenopus tropicalis, 52.8); CG15269 (Drosophila melanogaster, 50.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1326728-1328287:+ | gene-YDR463W_AKU4011 | rna-NM_001180771.3_AKU4011 | cds-NP_010751.4_AKU4011 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:234837-236396:+ | gene-YDR463W_BG1 | rna-NM_001180771.3_BG1 | cds-NP_010751.4_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1358149-1359708:+ | gene-YDR463W_Bruggeman | rna-NM_001180771.3_Bruggeman | cds-NP_010751.4_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1335293-1336852:+ | gene-YDR463W_CAT1 | rna-NM_001180771.3_CAT1 | cds-NP_010751.4_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1321033-1322592:+ | gene-YDR463W_CBS1585 | rna-NM_001180771.3_CBS1585 | cds-NP_010751.4_CBS1585 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1340401-1341960:+ | gene-YDR463W_CBS436 | rna-NM_001180771.3_CBS436 | cds-NP_010751.4_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1316660-1318219:+ | gene-YDR463W_CBS6412 | rna-NM_001180771.3_CBS6412 | cds-NP_010751.4_CBS6412 | 98.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1339671-1341230:+ | gene-YDR463W_CBS6413 | rna-NM_001180771.3_CBS6413 | cds-NP_010751.4_CBS6413 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1385512-1387071:+ | gene-YDR463W_CENPK1137D | rna-NM_001180771.3_CENPK1137D | cds-NP_010751.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1330076-1331635:+ | gene-YDR463W_EthanolRed | rna-NM_001180771.3_EthanolRed | cds-NP_010751.4_EthanolRed | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1333629-1335188:+ | gene-YDR463W_FaliES1 | rna-NM_001180771.3_FaliES1 | cds-NP_010751.4_FaliES1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:31887-33446:+ | gene-YDR463W_JAY291 | rna-NM_001180771.3_JAY291 | cds-NP_010751.4_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1340641-1342200:+ | gene-YDR463W_MUCL30387 | rna-NM_001180771.3_MUCL30387 | cds-NP_010751.4_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1322663-1324222:+ | gene-YDR463W_MUCL30388 | rna-NM_001180771.3_MUCL30388 | cds-NP_010751.4_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1312517-1314076:+ | gene-YDR463W_MUCL39482 | rna-NM_001180771.3_MUCL39482 | cds-NP_010751.4_MUCL39482 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1255317-1256876:+ | gene-YDR463W_MUCL42920 | rna-NM_001180771.3_MUCL42920 | cds-NP_010751.4_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1386739-1388298:+ | gene-YDR463W_NCIM3186 | rna-NM_001180771.3_NCIM3186 | cds-NP_010751.4_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1326290-1327849:+ | gene-YDR463W_NCYC1407 | rna-NM_001180771.3_NCYC1407 | cds-NP_010751.4_NCYC1407 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1337136-1338695:+ | gene-YDR463W_PE2H3 | rna-NM_001180771.3_PE2H3 | cds-NP_010751.4_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1342709-1344268:+ | gene-YDR463W_PE2H4 | rna-NM_001180771.3_PE2H4 | cds-NP_010751.4_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1386816-1388375:+ | gene-YDR463W_S288C | rna-NM_001180771.3_S288C | cds-NP_010751.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:228785-230344:- | gene-YDR463W_SA1 | rna-NM_001180771.3_SA1 | cds-NP_010751.4_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1337851-1339410:+ | gene-YDR463W_ThermosaccDry | rna-NM_001180771.3_ThermosaccDry | cds-NP_010751.4_ThermosaccDry | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1353579-1355138:+ | gene-YDR463W_VR1 | rna-NM_001180771.3_VR1 | cds-NP_010751.4_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:380524-382083:+ | gene-YDR463W_ZTW1 | rna-NM_001180771.3_ZTW1 | cds-NP_010751.4_ZTW1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1340924-1342486:+ | gene-YDR463W_Sparadoxus | rna-NM_001180771.3_Sparadoxus | cds-NP_010751.4_Sparadoxus | 88.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |