Gene name: STI1
Reference locus (S288C): YOR027W
Gene biotype: protein_coding
Description: Heat shock protein STI1; Hsp90 cochaperone; regulates spatial organization of amyloid-like proteins in the cytosol, thereby buffering the proteotoxicity caused by amyloid-like proteins; interacts with the Ssa group of the cytosolic Hsp70 chaperones and activates Ssa1p ATPase activity; interacts with Hsp90 chaperones and inhibits their ATPase activity; homolog of mammalian Hop
Top 10 interactors (score): HSC82 (0.999); SSE1 (0.999); AHA1 (0.999); HSP104 (0.999); SBA1 (0.999); CPR6 (0.999); YDJ1 (0.999); SIS1 (0.999); SSA1 (0.999); HSP82 (0.999); SSA2 (0.998); CDC37 (0.997); SSE2 (0.996); SSA4 (0.995); HSP78 (0.994); FES1 (0.993); HCH1 (0.992); SSA3 (0.991); CPR7 (0.987); HSP60 (0.972)
Homologues (species, bitscore): STIP1 (Homo sapiens, 380.9); Stip1 (Mus musculus, 381.3); stip1 (Danio rerio, 362.5); stip1 (Xenopus tropicalis, 385.6); Hop (Drosophila melanogaster, 312.4); sti-1 (Caenorhabditis elegans, 254.2); Hop3 (Arabidopsis thaliana, 399.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:365264-367033:+ | gene-YOR027W_AKU4011 | rna-NM_001183446.1_AKU4011 | cds-NP_014670.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:180846-182615:+ | gene-YOR027W_BG1 | rna-NM_001183446.1_BG1 | cds-NP_014670.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:368008-369777:+ | gene-YOR027W_Bruggeman | rna-NM_001183446.1_Bruggeman | cds-NP_014670.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:366164-367933:+ | gene-YOR027W_CAT1 | rna-NM_001183446.1_CAT1 | cds-NP_014670.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:359956-361725:+ | gene-YOR027W_CBS1585 | rna-NM_001183446.1_CBS1585 | cds-NP_014670.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:364315-366084:+ | gene-YOR027W_CBS436 | rna-NM_001183446.1_CBS436 | cds-NP_014670.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:359309-361078:+ | gene-YOR027W_CBS6412 | rna-NM_001183446.1_CBS6412 | cds-NP_014670.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:366685-368454:+ | gene-YOR027W_CBS6413 | rna-NM_001183446.1_CBS6413 | cds-NP_014670.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:380936-382705:+ | gene-YOR027W_CENPK1137D | rna-NM_001183446.1_CENPK1137D | cds-NP_014670.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:361966-363735:+ | gene-YOR027W_EthanolRed | rna-NM_001183446.1_EthanolRed | cds-NP_014670.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:365314-367083:+ | gene-YOR027W_FaliES1 | rna-NM_001183446.1_FaliES1 | cds-NP_014670.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000035.1:35962-37731:+ | gene-YOR027W_JAY291 | rna-NM_001183446.1_JAY291 | cds-NP_014670.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:372397-374166:+ | gene-YOR027W_MUCL30387 | rna-NM_001183446.1_MUCL30387 | cds-NP_014670.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:375830-377599:+ | gene-YOR027W_MUCL30388 | rna-NM_001183446.1_MUCL30388 | cds-NP_014670.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:367439-369208:+ | gene-YOR027W_MUCL39482 | rna-NM_001183446.1_MUCL39482 | cds-NP_014670.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:382254-384023:+ | gene-YOR027W_MUCL42920 | rna-NM_001183446.1_MUCL42920 | cds-NP_014670.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:380942-382711:+ | gene-YOR027W_NCIM3186 | rna-NM_001183446.1_NCIM3186 | cds-NP_014670.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:374141-375910:+ | gene-YOR027W_NCYC1407 | rna-NM_001183446.1_NCYC1407 | cds-NP_014670.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:372982-374751:+ | gene-YOR027W_PE2H3 | rna-NM_001183446.1_PE2H3 | cds-NP_014670.1_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:383361-385130:+ | gene-YOR027W_PE2H4 | rna-NM_001183446.1_PE2H4 | cds-NP_014670.1_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:381053-382822:+ | gene-YOR027W_S288C | rna-NM_001183446.1_S288C | cds-NP_014670.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:348848-350617:+ | gene-YOR027W_SA1 | rna-NM_001183446.1_SA1 | cds-NP_014670.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:363854-365623:+ | gene-YOR027W_ThermosaccDry | rna-NM_001183446.1_ThermosaccDry | cds-NP_014670.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:364743-366512:+ | gene-YOR027W_VR1 | rna-NM_001183446.1_VR1 | cds-NP_014670.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:98483-100252:+ | gene-YOR027W_ZTW1 | rna-NM_001183446.1_ZTW1 | cds-NP_014670.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:371014-372783:+ | gene-YOR027W_Sparadoxus | rna-NM_001183446.1_Sparadoxus | cds-NP_014670.1_Sparadoxus | 91.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |