STE7 (YDL159W)


Gene profile

Gene name: STE7
Reference locus (S288C): YDL159W
Gene biotype: protein_coding

Description: Serine/threonine-protein kinase STE7; Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway

Top 10 interactors (score): STE5 (0.999); KSS1 (0.999); FUS3 (0.999); STE11 (0.999); HOG1 (0.996); RAS2 (0.996); SLT2 (0.99); RAS1 (0.99); STE4 (0.982); STE12 (0.977); STE2 (0.972); CDC42 (0.966); SMK1 (0.965); GPA1 (0.923); STE3 (0.921); KDX1 (0.907); MSS4 (0.904); STE18 (0.903); FAR1 (0.898); CDC25 (0.895)

Homologues (species, bitscore): MAP2K1 (Homo sapiens, 225.7); Map2k2 (Mus musculus, 225.7); map2k1 (Danio rerio, 225.3); map2k1 (Xenopus tropicalis, 223.0); Dsor1 (Drosophila melanogaster, 217.2); mek-2 (Caenorhabditis elegans, 187.6); MKK3 (Arabidopsis thaliana, 185.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:156902-158449:+ gene-YDL159W_AKU4011 rna-NM_001180219.1_AKU4011 cds-NP_010122.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:391335-392882:- gene-YDL159W_BG1 rna-NM_001180219.1_BG1 cds-NP_010122.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:172947-174494:+ gene-YDL159W_Bruggeman rna-NM_001180219.1_Bruggeman cds-NP_010122.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:171263-172810:+ gene-YDL159W_CAT1 rna-NM_001180219.1_CAT1 cds-NP_010122.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:154933-156480:+ gene-YDL159W_CBS1585 rna-NM_001180219.1_CBS1585 cds-NP_010122.1_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:171872-173419:+ gene-YDL159W_CBS436 rna-NM_001180219.1_CBS436 cds-NP_010122.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:154186-155733:+ gene-YDL159W_CBS6412 rna-NM_001180219.1_CBS6412 cds-NP_010122.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:173371-174918:+ gene-YDL159W_CBS6413 rna-NM_001180219.1_CBS6413 cds-NP_010122.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:171133-172680:+ gene-YDL159W_CENPK1137D rna-NM_001180219.1_CENPK1137D cds-NP_010122.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:168141-169688:+ gene-YDL159W_EthanolRed rna-NM_001180219.1_EthanolRed cds-NP_010122.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:173673-175220:+ gene-YDL159W_FaliES1 rna-NM_001180219.1_FaliES1 cds-NP_010122.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000032.1:44335-45882:- gene-YDL159W_JAY291 rna-NM_001180219.1_JAY291 cds-NP_010122.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:171261-172808:+ gene-YDL159W_MUCL30387 rna-NM_001180219.1_MUCL30387 cds-NP_010122.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:162919-164466:+ gene-YDL159W_MUCL30388 rna-NM_001180219.1_MUCL30388 cds-NP_010122.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:156088-157635:+ gene-YDL159W_MUCL39482 rna-NM_001180219.1_MUCL39482 cds-NP_010122.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe MBVV01000307.1:11755-13302:- gene-YDL159W_MUCL42920 rna-NM_001180219.1_MUCL42920 cds-NP_010122.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:172404-173951:+ gene-YDL159W_NCIM3186 rna-NM_001180219.1_NCIM3186 cds-NP_010122.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:156021-157568:+ gene-YDL159W_NCYC1407 rna-NM_001180219.1_NCYC1407 cds-NP_010122.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:163256-164803:+ gene-YDL159W_PE2H3 rna-NM_001180219.1_PE2H3 cds-NP_010122.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:163260-164807:+ gene-YDL159W_PE2H4 rna-NM_001180219.1_PE2H4 cds-NP_010122.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:172481-174028:+ gene-YDL159W_S288C rna-NM_001180219.1_S288C cds-NP_010122.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000043.1:38040-39587:+ gene-YDL159W_SA1 rna-NM_001180219.1_SA1 cds-NP_010122.1_SA1 99.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:173434-174981:+ gene-YDL159W_ThermosaccDry rna-NM_001180219.1_ThermosaccDry cds-NP_010122.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:174027-175574:+ gene-YDL159W_VR1 rna-NM_001180219.1_VR1 cds-NP_010122.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:171561-173108:+ gene-YDL159W_ZTW1 rna-NM_001180219.1_ZTW1 cds-NP_010122.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:173699-175246:+ gene-YDL159W_Sparadoxus rna-NM_001180219.1_Sparadoxus cds-NP_010122.1_Sparadoxus 91.4 100.0 Verified 1 1 1 False True False False False

Additional files