Gene name: STE6
Reference locus (S288C): YKL209C
Gene biotype: protein_coding
Description: Alpha-factor-transporting ATPase; Plasma membrane ATP-binding cassette (ABC) transporter; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates multidrug resistance in many chemotherapy-resistant tumors by effluxing toxic compounds from the cell
Top 10 interactors (score): STE2 (0.998); MFA2 (0.981); MFA1 (0.979); BAR1 (0.975); AGA2 (0.954); MDR1 (0.947); STE14 (0.945); RAM2 (0.913); AXL1 (0.885); RFA1 (0.884); TAF1 (0.882); HMRA1 (0.876); RAM1 (0.868); CDC48 (0.864); STE24 (0.846); PDR5 (0.846); STE3 (0.839); MF(ALPHA)1 (0.817); SLA2 (0.806); SSM4 (0.805)
Homologues (species, bitscore): ABCB1 (Homo sapiens, 463.8); Abcb1b (Mus musculus, 466.8); abcb4 (Danio rerio, 469.5); abcb5 (Xenopus tropicalis, 459.5); Mdr50 (Drosophila melanogaster, 450.3); pgp-1 (Caenorhabditis elegans, 485.3); ABCB4 (Arabidopsis thaliana, 481.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:28250-32122:- | gene-YKL209C_AKU4011 | rna-NM_001179774.1_AKU4011 | cds-NP_012713.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:5821-9693:- | gene-YKL209C_BG1 | rna-NM_001179774.1_BG1 | cds-NP_012713.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:46409-50281:- | gene-YKL209C_Bruggeman | rna-NM_001179774.1_Bruggeman | cds-NP_012713.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:41108-44980:- | gene-YKL209C_CAT1 | rna-NM_001179774.1_CAT1 | cds-NP_012713.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:40260-44132:- | gene-YKL209C_CBS1585 | rna-NM_001179774.1_CBS1585 | cds-NP_012713.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:39949-43821:- | gene-YKL209C_CBS436 | rna-NM_001179774.1_CBS436 | cds-NP_012713.1_CBS436 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:26048-29920:- | gene-YKL209C_CBS6412 | rna-NM_001179774.1_CBS6412 | cds-NP_012713.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:40897-44769:- | gene-YKL209C_CBS6413 | rna-NM_001179774.1_CBS6413 | cds-NP_012713.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:42201-46073:- | gene-YKL209C_CENPK1137D | rna-NM_001179774.1_CENPK1137D | cds-NP_012713.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:40221-44093:- | gene-YKL209C_EthanolRed | rna-NM_001179774.1_EthanolRed | cds-NP_012713.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:40280-44152:- | gene-YKL209C_FaliES1 | rna-NM_001179774.1_FaliES1 | cds-NP_012713.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:39893-43765:- | gene-YKL209C_JAY291 | rna-NM_001179774.1_JAY291 | cds-NP_012713.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:48454-52326:- | gene-YKL209C_MUCL30387 | rna-NM_001179774.1_MUCL30387 | cds-NP_012713.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:42783-46655:- | gene-YKL209C_MUCL30388 | rna-NM_001179774.1_MUCL30388 | cds-NP_012713.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:40319-44191:- | gene-YKL209C_MUCL39482 | rna-NM_001179774.1_MUCL39482 | cds-NP_012713.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:44100-47972:- | gene-YKL209C_MUCL42920 | rna-NM_001179774.1_MUCL42920 | cds-NP_012713.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:42412-46284:- | gene-YKL209C_NCIM3186 | rna-NM_001179774.1_NCIM3186 | cds-NP_012713.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:40341-44213:- | gene-YKL209C_NCYC1407 | rna-NM_001179774.1_NCYC1407 | cds-NP_012713.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:48528-52400:- | gene-YKL209C_PE2H3 | rna-NM_001179774.1_PE2H3 | cds-NP_012713.1_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:44726-48598:- | gene-YKL209C_PE2H4 | rna-NM_001179774.1_PE2H4 | cds-NP_012713.1_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:42423-46295:- | gene-YKL209C_S288C | rna-NM_001179774.1_S288C | cds-NP_012713.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000092.1:21579-25451:+ | gene-YKL209C_SA1 | rna-NM_001179774.1_SA1 | cds-NP_012713.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:41028-44900:- | gene-YKL209C_ThermosaccDry | rna-NM_001179774.1_ThermosaccDry | cds-NP_012713.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:40134-44006:- | gene-YKL209C_VR1 | rna-NM_001179774.1_VR1 | cds-NP_012713.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:39941-43813:- | gene-YKL209C_ZTW1 | rna-NM_001179774.1_ZTW1 | cds-NP_012713.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:48707-52579:- | gene-YKL209C_Sparadoxus | rna-NM_001179774.1_Sparadoxus | cds-NP_012713.1_Sparadoxus | 88.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |