Gene name: STE4
Reference locus (S288C): YOR212W
Gene biotype: protein_coding
Description: G protein beta subunit; forms a dimer with Ste18p to activate mating signaling pathway, forms heterotrimer with Gpa1p and Ste18p to dampen signaling; pheromone-induced phosphorylation plays critical role in chemotropism; may recruit Rho1p to polarized growth site during mating; contains WD40 repeats
Top 10 interactors (score): STE18 (0.999); GPA2 (0.999); SST2 (0.999); GPA1 (0.999); STE5 (0.999); STE20 (0.997); STE2 (0.994); FAR1 (0.993); FUS3 (0.991); ASC1 (0.991); RGS2 (0.985); STE7 (0.982); YNK1 (0.978); CDC24 (0.973); STE11 (0.969); KSS1 (0.967); BCY1 (0.967); STE3 (0.959); CYR1 (0.959); CDC42 (0.95)
Homologues (species, bitscore): GNB5 (Homo sapiens, 253.4); Gnb5 (Mus musculus, 250.8); gnb5b (Danio rerio, 255.8); gnb5 (Xenopus tropicalis, 250.4); Gbeta13F (Drosophila melanogaster, 240.7); gpb-1 (Caenorhabditis elegans, 251.9); AGB1 (Arabidopsis thaliana, 200.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:733694-734965:+ | gene-YOR212W_AKU4011 | rna-NM_001183631.3_AKU4011 | cds-NP_014855.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:135730-137001:+ | gene-YOR212W_BG1 | rna-NM_001183631.3_BG1 | cds-NP_014855.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:718529-719800:+ | gene-YOR212W_Bruggeman | rna-NM_001183631.3_Bruggeman | cds-NP_014855.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:719805-721076:+ | gene-YOR212W_CAT1 | rna-NM_001183631.3_CAT1 | cds-NP_014855.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:716682-717953:+ | gene-YOR212W_CBS1585 | rna-NM_001183631.3_CBS1585 | cds-NP_014855.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:715370-716641:+ | gene-YOR212W_CBS436 | rna-NM_001183631.3_CBS436 | cds-NP_014855.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:713800-715071:+ | gene-YOR212W_CBS6412 | rna-NM_001183631.3_CBS6412 | cds-NP_014855.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:722440-723711:+ | gene-YOR212W_CBS6413 | rna-NM_001183631.3_CBS6413 | cds-NP_014855.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:742670-743941:+ | gene-YOR212W_CENPK1137D | rna-NM_001183631.3_CENPK1137D | cds-NP_014855.3_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:709834-711105:+ | gene-YOR212W_EthanolRed | rna-NM_001183631.3_EthanolRed | cds-NP_014855.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:715231-716502:+ | gene-YOR212W_FaliES1 | rna-NM_001183631.3_FaliES1 | cds-NP_014855.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:110260-111531:- | gene-YOR212W_JAY291 | rna-NM_001183631.3_JAY291 | cds-NP_014855.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:722494-723765:+ | gene-YOR212W_MUCL30387 | rna-NM_001183631.3_MUCL30387 | cds-NP_014855.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:729911-731182:+ | gene-YOR212W_MUCL30388 | rna-NM_001183631.3_MUCL30388 | cds-NP_014855.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:724011-725282:+ | gene-YOR212W_MUCL39482 | rna-NM_001183631.3_MUCL39482 | cds-NP_014855.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:733592-734863:+ | gene-YOR212W_MUCL42920 | rna-NM_001183631.3_MUCL42920 | cds-NP_014855.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:742799-744070:+ | gene-YOR212W_NCIM3186 | rna-NM_001183631.3_NCIM3186 | cds-NP_014855.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:724112-725383:+ | gene-YOR212W_NCYC1407 | rna-NM_001183631.3_NCYC1407 | cds-NP_014855.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:723503-724774:+ | gene-YOR212W_PE2H3 | rna-NM_001183631.3_PE2H3 | cds-NP_014855.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:733880-735151:+ | gene-YOR212W_PE2H4 | rna-NM_001183631.3_PE2H4 | cds-NP_014855.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:742910-744181:+ | gene-YOR212W_S288C | rna-NM_001183631.3_S288C | cds-NP_014855.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:152910-154181:+ | gene-YOR212W_SA1 | rna-NM_001183631.3_SA1 | cds-NP_014855.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:714416-715687:+ | gene-YOR212W_ThermosaccDry | rna-NM_001183631.3_ThermosaccDry | cds-NP_014855.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:777944-779215:+ | gene-YOR212W_VR1 | rna-NM_001183631.3_VR1 | cds-NP_014855.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:447319-448589:+ | gene-YOR212W_ZTW1 | rna-NM_001183631.3_ZTW1 | cds-NP_014855.3_ZTW1 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:720251-721522:+ | gene-YOR212W_Sparadoxus | rna-NM_001183631.3_Sparadoxus | cds-NP_014855.3_Sparadoxus | 91.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |