Gene name: STE23
Reference locus (S288C): YLR389C
Gene biotype: protein_coding
Description: A-factor-processing enzyme; Metalloprotease; involved in N-terminal processing of pro-a-factor to mature form; expressed in both haploids and diploids; one of two yeast homologs of human insulin-degrading enzyme (hIDE); homolog Axl1p is also involved in processing of pro-a-factor; Belongs to the peptidase M16 family
Top 10 interactors (score): STE24 (0.972); RCE1 (0.964); PXP1 (0.955); FMS1 (0.914); SPS19 (0.906); TES1 (0.905); CAT2 (0.904); CTT1 (0.902); PCD1 (0.902); STE14 (0.902); IDP2 (0.901); FOX2 (0.9); NCP1 (0.9); FAT1 (0.9); POX1 (0.9); CYM1 (0.881); MRPL9 (0.835); RAM2 (0.761); KEX1 (0.761); YNL247W (0.749)
Homologues (species, bitscore): IDE (Homo sapiens, 714.9); Ide (Mus musculus, 718.0); ide (Danio rerio, 720.7); nrd1 (Xenopus tropicalis, 400.2); Ide (Drosophila melanogaster, 659.1); F44E7.4 (Caenorhabditis elegans, 576.6); AT2G41790 (Arabidopsis thaliana, 595.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:849113-852196:- | gene-YLR389C_AKU4011 | rna-NM_001182278.1_AKU4011 | cds-NP_013493.2_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:81292-84375:- | gene-YLR389C_BG1 | rna-NM_001182278.1_BG1 | cds-NP_013493.2_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:887419-890502:- | gene-YLR389C_Bruggeman | rna-NM_001182278.1_Bruggeman | cds-NP_013493.2_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:882945-886028:- | gene-YLR389C_CAT1 | rna-NM_001182278.1_CAT1 | cds-NP_013493.2_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:884709-887792:- | gene-YLR389C_CBS1585 | rna-NM_001182278.1_CBS1585 | cds-NP_013493.2_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:868350-871433:- | gene-YLR389C_CBS436 | rna-NM_001182278.1_CBS436 | cds-NP_013493.2_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:920750-923833:- | gene-YLR389C_CBS6412 | rna-NM_001182278.1_CBS6412 | cds-NP_013493.2_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:885000-888083:- | gene-YLR389C_CBS6413 | rna-NM_001182278.1_CBS6413 | cds-NP_013493.2_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:884389-887472:- | gene-YLR389C_CENPK1137D | rna-NM_001182278.1_CENPK1137D | cds-NP_013493.2_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:841656-844739:- | gene-YLR389C_EthanolRed | rna-NM_001182278.1_EthanolRed | cds-NP_013493.2_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:870966-874049:- | gene-YLR389C_FaliES1 | rna-NM_001182278.1_FaliES1 | cds-NP_013493.2_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000434.1:24123-27206:- | gene-YLR389C_JAY291 | rna-NM_001182278.1_JAY291 | cds-NP_013493.2_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:886285-889368:- | gene-YLR389C_MUCL30387 | rna-NM_001182278.1_MUCL30387 | cds-NP_013493.2_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:892371-895454:- | gene-YLR389C_MUCL30388 | rna-NM_001182278.1_MUCL30388 | cds-NP_013493.2_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:885929-889012:- | gene-YLR389C_MUCL39482 | rna-NM_001182278.1_MUCL39482 | cds-NP_013493.2_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:880586-883669:- | gene-YLR389C_MUCL42920 | rna-NM_001182278.1_MUCL42920 | cds-NP_013493.2_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:899551-902634:- | gene-YLR389C_NCIM3186 | rna-NM_001182278.1_NCIM3186 | cds-NP_013493.2_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:895109-898192:- | gene-YLR389C_NCYC1407 | rna-NM_001182278.1_NCYC1407 | cds-NP_013493.2_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:881503-884586:- | gene-YLR389C_PE2H3 | rna-NM_001182278.1_PE2H3 | cds-NP_013493.2_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:881247-884330:- | gene-YLR389C_PE2H4 | rna-NM_001182278.1_PE2H4 | cds-NP_013493.2_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:899577-902660:- | gene-YLR389C_S288C | rna-NM_001182278.1_S288C | cds-NP_013493.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:146028-149111:+ | gene-YLR389C_SA1 | rna-NM_001182278.1_SA1 | cds-NP_013493.2_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:874045-877128:- | gene-YLR389C_ThermosaccDry | rna-NM_001182278.1_ThermosaccDry | cds-NP_013493.2_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:886593-889676:- | gene-YLR389C_VR1 | rna-NM_001182278.1_VR1 | cds-NP_013493.2_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:210761-213844:- | gene-YLR389C_ZTW1 | rna-NM_001182278.1_ZTW1 | cds-NP_013493.2_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:859471-862554:- | gene-YLR389C_Sparadoxus | rna-NM_001182278.1_Sparadoxus | cds-NP_013493.2_Sparadoxus | 90.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |