Gene name: STE20
Reference locus (S288C): YHL007C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase STE20; Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family
Top 10 interactors (score): CDC42 (0.999); BEM1 (0.999); STE4 (0.997); SHO1 (0.994); STE5 (0.989); CLA4 (0.985); STE11 (0.985); CDC24 (0.981); STE12 (0.978); HOG1 (0.977); NBP2 (0.975); SLT2 (0.969); STE18 (0.968); BMH1 (0.964); MYO1 (0.942); SMK1 (0.94); RAS2 (0.94); STE50 (0.94); MLC1 (0.936); BMH2 (0.934)
Homologues (species, bitscore): PAK1 (Homo sapiens, 442.6); Pak1 (Mus musculus, 456.4); ENSDARP00000006253 (Danio rerio, 461.8); pak3 (Xenopus tropicalis, 448.7); Pak (Drosophila melanogaster, 430.3); pak-1 (Caenorhabditis elegans, 436.4); SIK1 (Arabidopsis thaliana, 236.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:83733-86552:- | gene-YHL007C_AKU4011 | rna-NM_001179087.1_AKU4011 | cds-NP_011856.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:3434-6253:- | gene-YHL007C_BG1 | rna-NM_001179087.1_BG1 | cds-NP_011856.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:90587-93406:- | gene-YHL007C_Bruggeman | rna-NM_001179087.1_Bruggeman | cds-NP_011856.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:84560-87379:- | gene-YHL007C_CAT1 | rna-NM_001179087.1_CAT1 | cds-NP_011856.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:84320-87139:- | gene-YHL007C_CBS1585 | rna-NM_001179087.1_CBS1585 | cds-NP_011856.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:76810-79629:- | gene-YHL007C_CBS436 | rna-NM_001179087.1_CBS436 | cds-NP_011856.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:83920-86739:- | gene-YHL007C_CBS6412 | rna-NM_001179087.1_CBS6412 | cds-NP_011856.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:83644-86463:- | gene-YHL007C_CBS6413 | rna-NM_001179087.1_CBS6413 | cds-NP_011856.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:88279-91098:- | gene-YHL007C_CENPK1137D | rna-NM_001179087.1_CENPK1137D | cds-NP_011856.1_CENPK1137D | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:83728-86547:- | gene-YHL007C_EthanolRed | rna-NM_001179087.1_EthanolRed | cds-NP_011856.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:84257-87076:- | gene-YHL007C_FaliES1 | rna-NM_001179087.1_FaliES1 | cds-NP_011856.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000422.1:6911-9730:+ | gene-YHL007C_JAY291 | rna-NM_001179087.1_JAY291 | cds-NP_011856.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:87327-90146:- | gene-YHL007C_MUCL30387 | rna-NM_001179087.1_MUCL30387 | cds-NP_011856.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:88535-91354:- | gene-YHL007C_MUCL30388 | rna-NM_001179087.1_MUCL30388 | cds-NP_011856.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:83346-86165:- | gene-YHL007C_MUCL39482 | rna-NM_001179087.1_MUCL39482 | cds-NP_011856.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:87243-90062:- | gene-YHL007C_MUCL42920 | rna-NM_001179087.1_MUCL42920 | cds-NP_011856.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:95000-97819:- | gene-YHL007C_NCIM3186 | rna-NM_001179087.1_NCIM3186 | cds-NP_011856.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:82765-85584:- | gene-YHL007C_NCYC1407 | rna-NM_001179087.1_NCYC1407 | cds-NP_011856.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:84953-87772:- | gene-YHL007C_PE2H3 | rna-NM_001179087.1_PE2H3 | cds-NP_011856.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:92394-95213:- | gene-YHL007C_PE2H4 | rna-NM_001179087.1_PE2H4 | cds-NP_011856.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:95118-97937:- | gene-YHL007C_S288C | rna-NM_001179087.1_S288C | cds-NP_011856.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000075.1:48618-51437:+ | gene-YHL007C_SA1 | rna-NM_001179087.1_SA1 | cds-NP_011856.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:85347-88166:- | gene-YHL007C_ThermosaccDry | rna-NM_001179087.1_ThermosaccDry | cds-NP_011856.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:90880-93699:- | gene-YHL007C_VR1 | rna-NM_001179087.1_VR1 | cds-NP_011856.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:76513-79332:- | gene-YHL007C_ZTW1 | rna-NM_001179087.1_ZTW1 | cds-NP_011856.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:83041-85869:- | gene-YHL007C_Sparadoxus | rna-NM_001179087.1_Sparadoxus | cds-NP_011856.1_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |