Gene name: STE11
Reference locus (S288C): YLR362W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase STE11; Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): SHO1 (0.999); STE50 (0.999); STE5 (0.999); STE7 (0.999); RAS2 (0.998); RAS1 (0.997); PBS2 (0.995); CDC42 (0.994); SSK1 (0.989); STE12 (0.989); STE20 (0.985); MKK1 (0.98); STE4 (0.969); MKK2 (0.968); FUS3 (0.959); CLA4 (0.954); STE2 (0.949); GPA1 (0.948); HSP82 (0.93); CDC37 (0.93)
Homologues (species, bitscore): MAP3K3 (Homo sapiens, 232.6); Map3k3 (Mus musculus, 232.6); map3k3 (Danio rerio, 233.0); Map3k3 (Xenopus tropicalis, 228.4); Pk92B (Drosophila melanogaster, 173.7); nsy-1 (Caenorhabditis elegans, 167.5); NP1 (Arabidopsis thaliana, 260.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:799414-801567:+ | gene-YLR362W_AKU4011 | rna-NM_001182251.1_AKU4011 | cds-NP_013466.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:31555-33708:+ | gene-YLR362W_BG1 | rna-NM_001182251.1_BG1 | cds-NP_013466.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:837727-839880:+ | gene-YLR362W_Bruggeman | rna-NM_001182251.1_Bruggeman | cds-NP_013466.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:833231-835384:+ | gene-YLR362W_CAT1 | rna-NM_001182251.1_CAT1 | cds-NP_013466.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:834406-836559:+ | gene-YLR362W_CBS1585 | rna-NM_001182251.1_CBS1585 | cds-NP_013466.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:818636-820789:+ | gene-YLR362W_CBS436 | rna-NM_001182251.1_CBS436 | cds-NP_013466.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:871413-873566:+ | gene-YLR362W_CBS6412 | rna-NM_001182251.1_CBS6412 | cds-NP_013466.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:835297-837450:+ | gene-YLR362W_CBS6413 | rna-NM_001182251.1_CBS6413 | cds-NP_013466.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:834567-836754:+ | gene-YLR362W_CENPK1137D | rna-NM_001182251.1_CENPK1137D | cds-NP_013466.1_CENPK1137D | 98.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:791973-794126:+ | gene-YLR362W_EthanolRed | rna-NM_001182251.1_EthanolRed | cds-NP_013466.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:820778-822931:+ | gene-YLR362W_FaliES1 | rna-NM_001182251.1_FaliES1 | cds-NP_013466.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000161.1:31372-33525:+ | gene-YLR362W_JAY291 | rna-NM_001182251.1_JAY291 | cds-NP_013466.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:835142-837295:+ | gene-YLR362W_MUCL30387 | rna-NM_001182251.1_MUCL30387 | cds-NP_013466.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:840760-842913:+ | gene-YLR362W_MUCL30388 | rna-NM_001182251.1_MUCL30388 | cds-NP_013466.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:835625-837778:+ | gene-YLR362W_MUCL39482 | rna-NM_001182251.1_MUCL39482 | cds-NP_013466.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:830900-833053:+ | gene-YLR362W_MUCL42920 | rna-NM_001182251.1_MUCL42920 | cds-NP_013466.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:849840-851993:+ | gene-YLR362W_NCIM3186 | rna-NM_001182251.1_NCIM3186 | cds-NP_013466.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:844845-846998:+ | gene-YLR362W_NCYC1407 | rna-NM_001182251.1_NCYC1407 | cds-NP_013466.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:831793-833946:+ | gene-YLR362W_PE2H3 | rna-NM_001182251.1_PE2H3 | cds-NP_013466.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:831537-833690:+ | gene-YLR362W_PE2H4 | rna-NM_001182251.1_PE2H4 | cds-NP_013466.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:849866-852019:+ | gene-YLR362W_S288C | rna-NM_001182251.1_S288C | cds-NP_013466.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:196670-198823:- | gene-YLR362W_SA1 | rna-NM_001182251.1_SA1 | cds-NP_013466.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:823619-825772:+ | gene-YLR362W_ThermosaccDry | rna-NM_001182251.1_ThermosaccDry | cds-NP_013466.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:836882-839035:+ | gene-YLR362W_VR1 | rna-NM_001182251.1_VR1 | cds-NP_013466.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:161061-163214:+ | gene-YLR362W_ZTW1 | rna-NM_001182251.1_ZTW1 | cds-NP_013466.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:809667-811820:+ | gene-YLR362W_Sparadoxus | rna-NM_001182251.1_Sparadoxus | cds-NP_013466.1_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |