SSS1 (YDR086C)


Gene profile

Gene name: SSS1
Reference locus (S288C): YDR086C
Gene biotype: protein_coding

Description: Protein transport protein SSS1; Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p); this complex forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p; Belongs to the SecE/SEC61-gamma family

Top 10 interactors (score): SBH1 (0.999); SEC61 (0.999); SBH2 (0.999); SEC63 (0.999); SSH1 (0.998); SEC62 (0.998); RPL29 (0.996); RPL30 (0.996); RPL25 (0.994); RPL38 (0.992); SEC72 (0.99); RPL39 (0.988); SEC66 (0.983); KAR2 (0.983); RPL35B (0.983); RPL35A (0.981); RPL42A (0.975); RPL31A (0.972); RPL42B (0.971); RPL26A (0.97)

Homologues (species, bitscore): SEC61G (Homo sapiens, 66.2); Sec61g (Mus musculus, 67.8); sec61g (Danio rerio, 66.2); sec61g (Xenopus tropicalis, 66.6); Sec61gamma (Drosophila melanogaster, 58.9); emo-1 (Caenorhabditis elegans, 65.5); SEC61G1 (Arabidopsis thaliana, 58.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:594487-594729:- gene-YDR086C_AKU4011 rna-NM_001180394.1_AKU4011 cds-NP_010371.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:530589-530831:+ gene-YDR086C_BG1 rna-NM_001180394.1_BG1 cds-NP_010371.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:626714-626956:- gene-YDR086C_Bruggeman rna-NM_001180394.1_Bruggeman cds-NP_010371.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:611402-611644:- gene-YDR086C_CAT1 rna-NM_001180394.1_CAT1 cds-NP_010371.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:585508-585750:- gene-YDR086C_CBS1585 rna-NM_001180394.1_CBS1585 cds-NP_010371.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:610522-610764:- gene-YDR086C_CBS436 rna-NM_001180394.1_CBS436 cds-NP_010371.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:581921-582163:- gene-YDR086C_CBS6412 rna-NM_001180394.1_CBS6412 cds-NP_010371.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:610453-610695:- gene-YDR086C_CBS6413 rna-NM_001180394.1_CBS6413 cds-NP_010371.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:615973-616215:- gene-YDR086C_CENPK1137D rna-NM_001180394.1_CENPK1137D cds-NP_010371.1_CENPK1137D 99.5 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:596278-596520:- gene-YDR086C_EthanolRed rna-NM_001180394.1_EthanolRed cds-NP_010371.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:603072-603314:- gene-YDR086C_FaliES1 rna-NM_001180394.1_FaliES1 cds-NP_010371.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000358.1:27955-28197:+ gene-YDR086C_JAY291 rna-NM_001180394.1_JAY291 cds-NP_010371.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:611331-611573:- gene-YDR086C_MUCL30387 rna-NM_001180394.1_MUCL30387 cds-NP_010371.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:601643-601885:- gene-YDR086C_MUCL30388 rna-NM_001180394.1_MUCL30388 cds-NP_010371.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:586878-587120:- gene-YDR086C_MUCL39482 rna-NM_001180394.1_MUCL39482 cds-NP_010371.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:518327-518569:- gene-YDR086C_MUCL42920 rna-NM_001180394.1_MUCL42920 cds-NP_010371.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:616851-617093:- gene-YDR086C_NCIM3186 rna-NM_001180394.1_NCIM3186 cds-NP_010371.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:585785-586027:- gene-YDR086C_NCYC1407 rna-NM_001180394.1_NCYC1407 cds-NP_010371.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:605253-605495:- gene-YDR086C_PE2H3 rna-NM_001180394.1_PE2H3 cds-NP_010371.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:604558-604800:- gene-YDR086C_PE2H4 rna-NM_001180394.1_PE2H4 cds-NP_010371.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:616928-617170:- gene-YDR086C_S288C rna-NM_001180394.1_S288C cds-NP_010371.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:28164-28406:+ gene-YDR086C_SA1 rna-NM_001180394.1_SA1 cds-NP_010371.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:602602-602844:- gene-YDR086C_ThermosaccDry rna-NM_001180394.1_ThermosaccDry cds-NP_010371.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:615153-615395:- gene-YDR086C_VR1 rna-NM_001180394.1_VR1 cds-NP_010371.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:600185-600427:- gene-YDR086C_ZTW1 rna-NM_001180394.1_ZTW1 cds-NP_010371.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:604908-605150:- gene-YDR086C_Sparadoxus rna-NM_001180394.1_Sparadoxus cds-NP_010371.1_Sparadoxus 95.0 100.0 Verified 1 1 1 False True False False False

Additional files