Gene name: SSN8
Reference locus (S288C): YNL025C
Gene biotype: protein_coding
Description: Cyclin-dependent protein serine/threonine kinase regulator ssn8; Cyclin-like component of the RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; forms a kinase-cyclin pair in the RNAPII holoenzyme with Ssn3p; required for both entry into and execution of the meiotic program; involved in glucose repression and telomere maintenance; cyclin homolog 35% identical to human cyclin C
Top 10 interactors (score): SSN3 (0.999); MED6 (0.999); MED7 (0.999); SRB8 (0.999); SSN2 (0.999); NUT2 (0.998); SIN4 (0.996); RGR1 (0.994); SRB7 (0.993); KIN28 (0.991); NUT1 (0.991); SOH1 (0.972); MED2 (0.93); ROX3 (0.93); PHO85 (0.923); CTK2 (0.915); SFL1 (0.914); CDC28 (0.894); GAL11 (0.867); SRB6 (0.854)
Homologues (species, bitscore): CCNC (Homo sapiens, 123.6); Ccnc (Mus musculus, 123.2); ccnc (Danio rerio, 125.2); ccnc (Xenopus tropicalis, 124.4); CycC (Drosophila melanogaster, 123.6); cic-1 (Caenorhabditis elegans, 87.0); AT5G48640 (Arabidopsis thaliana, 97.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:566779-567750:- | gene-YNL025C_AKU4011 | rna-NM_001182864.3_AKU4011 | cds-NP_014373.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:472390-473361:+ | gene-YNL025C_BG1 | rna-NM_001182864.3_BG1 | cds-NP_014373.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:584200-585171:- | gene-YNL025C_Bruggeman | rna-NM_001182864.3_Bruggeman | cds-NP_014373.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:619652-620623:- | gene-YNL025C_CAT1 | rna-NM_001182864.3_CAT1 | cds-NP_014373.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:572463-573434:- | gene-YNL025C_CBS1585 | rna-NM_001182864.3_CBS1585 | cds-NP_014373.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:634877-635848:- | gene-YNL025C_CBS436 | rna-NM_001182864.3_CBS436 | cds-NP_014373.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:562296-563267:- | gene-YNL025C_CBS6412 | rna-NM_001182864.3_CBS6412 | cds-NP_014373.3_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:563637-564608:- | gene-YNL025C_CBS6413 | rna-NM_001182864.3_CBS6413 | cds-NP_014373.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:577927-578898:- | gene-YNL025C_CENPK1137D | rna-NM_001182864.3_CENPK1137D | cds-NP_014373.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:568865-569836:- | gene-YNL025C_EthanolRed | rna-NM_001182864.3_EthanolRed | cds-NP_014373.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:559889-560860:- | gene-YNL025C_FaliES1 | rna-NM_001182864.3_FaliES1 | cds-NP_014373.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000387.1:12973-13944:+ | gene-YNL025C_JAY291 | rna-NM_001182864.3_JAY291 | cds-NP_014373.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:580082-581053:- | gene-YNL025C_MUCL30387 | rna-NM_001182864.3_MUCL30387 | cds-NP_014373.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:622876-623847:- | gene-YNL025C_MUCL30388 | rna-NM_001182864.3_MUCL30388 | cds-NP_014373.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:564058-565029:- | gene-YNL025C_MUCL39482 | rna-NM_001182864.3_MUCL39482 | cds-NP_014373.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:567620-568591:- | gene-YNL025C_MUCL42920 | rna-NM_001182864.3_MUCL42920 | cds-NP_014373.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:584289-585260:- | gene-YNL025C_NCIM3186 | rna-NM_001182864.3_NCIM3186 | cds-NP_014373.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:566263-567234:- | gene-YNL025C_NCYC1407 | rna-NM_001182864.3_NCYC1407 | cds-NP_014373.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:568790-569761:- | gene-YNL025C_PE2H3 | rna-NM_001182864.3_PE2H3 | cds-NP_014373.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:570105-571076:- | gene-YNL025C_PE2H4 | rna-NM_001182864.3_PE2H4 | cds-NP_014373.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:584320-585291:- | gene-YNL025C_S288C | rna-NM_001182864.3_S288C | cds-NP_014373.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000109.1:10349-11320:- | gene-YNL025C_SA1 | rna-NM_001182864.3_SA1 | cds-NP_014373.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:560476-561447:- | gene-YNL025C_ThermosaccDry | rna-NM_001182864.3_ThermosaccDry | cds-NP_014373.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:581300-582271:+ | gene-YNL025C_VR1 | rna-NM_001182864.3_VR1 | cds-NP_014373.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:471993-472964:+ | gene-YNL025C_ZTW1 | rna-NM_001182864.3_ZTW1 | cds-NP_014373.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:575523-576494:- | gene-YNL025C_Sparadoxus | rna-NM_001182864.3_Sparadoxus | cds-NP_014373.3_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |