SSL1 (YLR005W)


Gene profile

Gene name: SSL1
Reference locus (S288C): YLR005W
Gene biotype: protein_coding

Description: Suppressor of stem-loop protein 1; Subunit of the core form of RNA polymerase transcription factor TFIIH; has both protein kinase and DNA-dependent ATPase/helicase activities; essential for transcription and nucleotide excision repair; interacts with Tfb4p; Belongs to the GTF2H2 family

Top 10 interactors (score): SSL2 (0.999); KIN28 (0.999); TFA1 (0.999); TFB3 (0.999); CCL1 (0.999); TFB1 (0.999); TFB4 (0.999); RAD3 (0.999); TFB5 (0.999); TFB2 (0.999); TFA2 (0.999); RAD2 (0.993); RAD14 (0.984); TFG1 (0.974); RAD4 (0.972); TFB6 (0.968); TOA2 (0.967); RAD7 (0.959); RAD10 (0.957); RAD23 (0.95)

Homologues (species, bitscore): GTF2H2C (Homo sapiens, 295.4); Gtf2h2 (Mus musculus, 293.9); gtf2h2 (Danio rerio, 292.0); gtf2h2 (Xenopus tropicalis, 248.1); Ssl1 (Drosophila melanogaster, 272.7); T16H12.4 (Caenorhabditis elegans, 241.9); GTF2H2 (Arabidopsis thaliana, 300.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:148028-149413:+ gene-YLR005W_AKU4011 rna-NM_001181892.1_AKU4011 cds-NP_013105.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:111238-112623:+ gene-YLR005W_BG1 rna-NM_001181892.1_BG1 cds-NP_013105.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:158400-159785:+ gene-YLR005W_Bruggeman rna-NM_001181892.1_Bruggeman cds-NP_013105.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:158719-160104:+ gene-YLR005W_CAT1 rna-NM_001181892.1_CAT1 cds-NP_013105.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:155627-157012:+ gene-YLR005W_CBS1585 rna-NM_001181892.1_CBS1585 cds-NP_013105.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:146252-147637:+ gene-YLR005W_CBS436 rna-NM_001181892.1_CBS436 cds-NP_013105.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:154399-155784:+ gene-YLR005W_CBS6412 rna-NM_001181892.1_CBS6412 cds-NP_013105.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:155893-157278:+ gene-YLR005W_CBS6413 rna-NM_001181892.1_CBS6413 cds-NP_013105.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:145312-146697:+ gene-YLR005W_CENPK1137D rna-NM_001181892.1_CENPK1137D cds-NP_013105.1_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:148049-149434:+ gene-YLR005W_EthanolRed rna-NM_001181892.1_EthanolRed cds-NP_013105.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:147620-149005:+ gene-YLR005W_FaliES1 rna-NM_001181892.1_FaliES1 cds-NP_013105.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000083.1:6590-7975:- gene-YLR005W_JAY291 rna-NM_001181892.1_JAY291 cds-NP_013105.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:155756-157141:+ gene-YLR005W_MUCL30387 rna-NM_001181892.1_MUCL30387 cds-NP_013105.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:161453-162838:+ gene-YLR005W_MUCL30388 rna-NM_001181892.1_MUCL30388 cds-NP_013105.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:156098-157483:+ gene-YLR005W_MUCL39482 rna-NM_001181892.1_MUCL39482 cds-NP_013105.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:156026-157411:+ gene-YLR005W_MUCL42920 rna-NM_001181892.1_MUCL42920 cds-NP_013105.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:160023-161408:+ gene-YLR005W_NCIM3186 rna-NM_001181892.1_NCIM3186 cds-NP_013105.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:147701-149086:+ gene-YLR005W_NCYC1407 rna-NM_001181892.1_NCYC1407 cds-NP_013105.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:154049-155434:+ gene-YLR005W_PE2H3 rna-NM_001181892.1_PE2H3 cds-NP_013105.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:153790-155175:+ gene-YLR005W_PE2H4 rna-NM_001181892.1_PE2H4 cds-NP_013105.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:160049-161434:+ gene-YLR005W_S288C rna-NM_001181892.1_S288C cds-NP_013105.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000062.1:63247-64632:+ gene-YLR005W_SA1 rna-NM_001181892.1_SA1 cds-NP_013105.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:148123-149508:+ gene-YLR005W_ThermosaccDry rna-NM_001181892.1_ThermosaccDry cds-NP_013105.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:161501-162886:+ gene-YLR005W_VR1 rna-NM_001181892.1_VR1 cds-NP_013105.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:147457-148842:+ gene-YLR005W_ZTW1 rna-NM_001181892.1_ZTW1 cds-NP_013105.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:156070-157449:+ gene-YLR005W_Sparadoxus rna-NM_001181892.1_Sparadoxus cds-NP_013105.1_Sparadoxus 92.3 99.5 Verified 1 1 1 False True False False False

Additional files