Gene name: SSK22
Reference locus (S288C): YCR073C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase SSK22; MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication
Top 10 interactors (score): SSK1 (0.999); PBS2 (0.997); YPD1 (0.976); SLN1 (0.972); SHO1 (0.964); SSK2 (0.951); PTP3 (0.864); STE50 (0.86); OPY2 (0.812); CDC42 (0.803); STE20 (0.796); PTP2 (0.772); SKN7 (0.772); MSB2 (0.77); SKO1 (0.757); HKR1 (0.747); FPS1 (0.745); HOT1 (0.719); PTC1 (0.661); GCG1 (0.635)
Homologues (species, bitscore): MAP3K4 (Homo sapiens, 217.6); Mekk4 (Mus musculus, 219.2); map3k4 (Danio rerio, 212.2); map3k5 (Xenopus tropicalis, 169.1); Mekk1 (Drosophila melanogaster, 216.5); nsy-1 (Caenorhabditis elegans, 161.0); MAP3KA (Arabidopsis thaliana, 210.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:237103-241098:- | gene-YCR073C_AKU4011 | rna-NM_001178783.1_AKU4011 | cds-NP_009998.2_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000067.1:95776-99771:- | gene-YCR073C_BG1 | rna-NM_001178783.1_BG1 | cds-NP_009998.2_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:233312-237307:- | gene-YCR073C_Bruggeman | rna-NM_001178783.1_Bruggeman | cds-NP_009998.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:244380-248375:- | gene-YCR073C_CAT1 | rna-NM_001178783.1_CAT1 | cds-NP_009998.2_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:231880-235875:- | gene-YCR073C_CBS1585 | rna-NM_001178783.1_CBS1585 | cds-NP_009998.2_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:243716-247711:- | gene-YCR073C_CBS436 | rna-NM_001178783.1_CBS436 | cds-NP_009998.2_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:223620-227615:- | gene-YCR073C_CBS6412 | rna-NM_001178783.1_CBS6412 | cds-NP_009998.2_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:237968-241963:- | gene-YCR073C_CBS6413 | rna-NM_001178783.1_CBS6413 | cds-NP_009998.2_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:241829-245824:- | gene-YCR073C_CENPK1137D | rna-NM_001178783.1_CENPK1137D | cds-NP_009998.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:233073-237068:- | gene-YCR073C_EthanolRed | rna-NM_001178783.1_EthanolRed | cds-NP_009998.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:238235-242230:- | gene-YCR073C_FaliES1 | rna-NM_001178783.1_FaliES1 | cds-NP_009998.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000323.1:46497-50492:+ | gene-YCR073C_JAY291 | rna-NM_001178783.1_JAY291 | cds-NP_009998.2_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:230464-234459:- | gene-YCR073C_MUCL30387 | rna-NM_001178783.1_MUCL30387 | cds-NP_009998.2_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:230307-234302:- | gene-YCR073C_MUCL30388 | rna-NM_001178783.1_MUCL30388 | cds-NP_009998.2_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:238453-242448:- | gene-YCR073C_MUCL39482 | rna-NM_001178783.1_MUCL39482 | cds-NP_009998.2_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:234886-238881:- | gene-YCR073C_MUCL42920 | rna-NM_001178783.1_MUCL42920 | cds-NP_009998.2_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:242220-246215:- | gene-YCR073C_NCIM3186 | rna-NM_001178783.1_NCIM3186 | cds-NP_009998.2_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:239312-243307:- | gene-YCR073C_NCYC1407 | rna-NM_001178783.1_NCYC1407 | cds-NP_009998.2_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:253895-257890:- | gene-YCR073C_PE2H3 | rna-NM_001178783.1_PE2H3 | cds-NP_009998.2_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:242449-246444:- | gene-YCR073C_PE2H4 | rna-NM_001178783.1_PE2H4 | cds-NP_009998.2_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:242588-246583:- | gene-YCR073C_S288C | rna-NM_001178783.1_S288C | cds-NP_009998.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000044.1:42467-46462:- | gene-YCR073C_SA1 | rna-NM_001178783.1_SA1 | cds-NP_009998.2_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:238163-242158:- | gene-YCR073C_ThermosaccDry | rna-NM_001178783.1_ThermosaccDry | cds-NP_009998.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:249434-253429:- | gene-YCR073C_VR1 | rna-NM_001178783.1_VR1 | cds-NP_009998.2_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:236035-240030:- | gene-YCR073C_ZTW1 | rna-NM_001178783.1_ZTW1 | cds-NP_009998.2_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:270233-274231:- | gene-YCR073C_Sparadoxus | rna-NM_001178783.1_Sparadoxus | cds-NP_009998.2_Sparadoxus | 86.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |