SSE1 (YPL106C)


Gene profile

Gene name: SSE1
Reference locus (S288C): YPL106C
Gene biotype: protein_coding

Description: ATPase component of heat shock protein Hsp90 chaperone complex; serves as nucleotide exchange factor to load ATP onto the SSA class of cytosolic Hsp70s; plays a role in prion propagation and determining prion variants; binds unfolded proteins; member of Hsp110 subclass of HSP70 proteins; deletion results in spindle elongation in S phase; SSE1 has a paralog, SSE2, that arose from the whole genome duplication

Top 10 interactors (score): YDJ1 (0.999); HSC82 (0.999); SIS1 (0.999); STI1 (0.999); FES1 (0.998); HSP82 (0.997); ZUO1 (0.994); SGT2 (0.994); AHA1 (0.989); SSA1 (0.986); HSP104 (0.979); MDJ1 (0.975); XDJ1 (0.974); SBA1 (0.974); SNL1 (0.971); SSA2 (0.971); CCT8 (0.965); SSE2 (0.959); CCT7 (0.954); SUP35 (0.948)

Homologues (species, bitscore): HSPH1 (Homo sapiens, 477.2); Hsph1 (Mus musculus, 475.7); hspa4a (Danio rerio, 477.6); hsph1 (Xenopus tropicalis, 451.8); Hsc70Cb (Drosophila melanogaster, 435.3); C30C11.4 (Caenorhabditis elegans, 439.9); HSP91 (Arabidopsis thaliana, 482.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:327833-329914:- gene-YPL106C_AKU4011 rna-NM_001183920.1_AKU4011 cds-NP_015219.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:533589-535670:- gene-YPL106C_BG1 rna-NM_001183920.1_BG1 cds-NP_015219.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:353838-355919:- gene-YPL106C_Bruggeman rna-NM_001183920.1_Bruggeman cds-NP_015219.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:350505-352586:- gene-YPL106C_CAT1 rna-NM_001183920.1_CAT1 cds-NP_015219.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:331906-333987:- gene-YPL106C_CBS1585 rna-NM_001183920.1_CBS1585 cds-NP_015219.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:346581-348662:- gene-YPL106C_CBS436 rna-NM_001183920.1_CBS436 cds-NP_015219.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:336575-338656:- gene-YPL106C_CBS6412 rna-NM_001183920.1_CBS6412 cds-NP_015219.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:328542-330623:- gene-YPL106C_CBS6413 rna-NM_001183920.1_CBS6413 cds-NP_015219.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:350143-352224:- gene-YPL106C_CENPK1137D rna-NM_001183920.1_CENPK1137D cds-NP_015219.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:326524-328605:- gene-YPL106C_EthanolRed rna-NM_001183920.1_EthanolRed cds-NP_015219.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:334116-336197:- gene-YPL106C_FaliES1 rna-NM_001183920.1_FaliES1 cds-NP_015219.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:29620-31701:+ gene-YPL106C_JAY291 rna-NM_001183920.1_JAY291 cds-NP_015219.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:345078-347159:- gene-YPL106C_MUCL30387 rna-NM_001183920.1_MUCL30387 cds-NP_015219.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:343896-345977:- gene-YPL106C_MUCL30388 rna-NM_001183920.1_MUCL30388 cds-NP_015219.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:325235-327316:- gene-YPL106C_MUCL39482 rna-NM_001183920.1_MUCL39482 cds-NP_015219.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:382923-385004:- gene-YPL106C_MUCL42920 rna-NM_001183920.1_MUCL42920 cds-NP_015219.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:350177-352258:- gene-YPL106C_NCIM3186 rna-NM_001183920.1_NCIM3186 cds-NP_015219.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:331688-333769:- gene-YPL106C_NCYC1407 rna-NM_001183920.1_NCYC1407 cds-NP_015219.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:339180-341261:- gene-YPL106C_PE2H3 rna-NM_001183920.1_PE2H3 cds-NP_015219.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:338803-340884:- gene-YPL106C_PE2H4 rna-NM_001183920.1_PE2H4 cds-NP_015219.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:350194-352275:- gene-YPL106C_S288C rna-NM_001183920.1_S288C cds-NP_015219.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000012.1:21405-23486:+ gene-YPL106C_SA1 rna-NM_001183920.1_SA1 cds-NP_015219.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:333914-335995:- gene-YPL106C_ThermosaccDry rna-NM_001183920.1_ThermosaccDry cds-NP_015219.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:348892-350973:- gene-YPL106C_VR1 rna-NM_001183920.1_VR1 cds-NP_015219.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:333239-335320:- gene-YPL106C_ZTW1 rna-NM_001183920.1_ZTW1 cds-NP_015219.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:334941-337022:- gene-YPL106C_Sparadoxus rna-NM_001183920.1_Sparadoxus cds-NP_015219.1_Sparadoxus 93.1 100.0 Verified 1 1 1 False True False False False

Additional files