Gene name: SSA4
Reference locus (S288C): YER103W
Gene biotype: protein_coding
Description: Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation; SSA4 has a paralog, SSA3, that arose from the whole genome duplication
Top 10 interactors (score): SSA3 (0.999); HSP104 (0.998); SIS1 (0.997); HSP82 (0.996); STI1 (0.995); YDJ1 (0.994); HSP78 (0.993); HSC82 (0.99); HSP26 (0.988); HSF1 (0.987); ZUO1 (0.987); SSE2 (0.987); HSP42 (0.985); MDJ1 (0.97); APJ1 (0.97); XDJ1 (0.938); SKN7 (0.932); NUP82 (0.929); MGA1 (0.926); HMS2 (0.926)
Homologues (species, bitscore): HSPA8 (Homo sapiens, 1000.7); Hspa8 (Mus musculus, 998.4); hsp70 (Danio rerio, 986.1); hspa1b (Xenopus tropicalis, 1007.7); Hsc70-4 (Drosophila melanogaster, 982.2); hsp-1 (Caenorhabditis elegans, 1015.8); Hsp70b (Arabidopsis thaliana, 940.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:358474-360402:+ | gene-YER103W_AKU4011 | rna-NM_001178994.3_AKU4011 | cds-NP_011029.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:65205-67133:- | gene-YER103W_BG1 | rna-NM_001178994.3_BG1 | cds-NP_011029.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:368948-370876:+ | gene-YER103W_Bruggeman | rna-NM_001178994.3_Bruggeman | cds-NP_011029.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:363232-365160:+ | gene-YER103W_CAT1 | rna-NM_001178994.3_CAT1 | cds-NP_011029.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:357869-359797:+ | gene-YER103W_CBS1585 | rna-NM_001178994.3_CBS1585 | cds-NP_011029.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:360575-362503:+ | gene-YER103W_CBS436 | rna-NM_001178994.3_CBS436 | cds-NP_011029.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:356943-358871:+ | gene-YER103W_CBS6412 | rna-NM_001178994.3_CBS6412 | cds-NP_011029.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:363785-365713:+ | gene-YER103W_CBS6413 | rna-NM_001178994.3_CBS6413 | cds-NP_011029.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:362362-364290:+ | gene-YER103W_CENPK1137D | rna-NM_001178994.3_CENPK1137D | cds-NP_011029.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:358314-360242:+ | gene-YER103W_EthanolRed | rna-NM_001178994.3_EthanolRed | cds-NP_011029.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:358795-360723:+ | gene-YER103W_FaliES1 | rna-NM_001178994.3_FaliES1 | cds-NP_011029.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000174.1:30817-32745:- | gene-YER103W_JAY291 | rna-NM_001178994.3_JAY291 | cds-NP_011029.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:365896-367824:+ | gene-YER103W_MUCL30387 | rna-NM_001178994.3_MUCL30387 | cds-NP_011029.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:360828-362756:+ | gene-YER103W_MUCL30388 | rna-NM_001178994.3_MUCL30388 | cds-NP_011029.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:356893-358821:+ | gene-YER103W_MUCL39482 | rna-NM_001178994.3_MUCL39482 | cds-NP_011029.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:365385-367313:+ | gene-YER103W_MUCL42920 | rna-NM_001178994.3_MUCL42920 | cds-NP_011029.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:364588-366516:+ | gene-YER103W_NCIM3186 | rna-NM_001178994.3_NCIM3186 | cds-NP_011029.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:362426-364354:+ | gene-YER103W_NCYC1407 | rna-NM_001178994.3_NCYC1407 | cds-NP_011029.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:372966-374894:+ | gene-YER103W_PE2H3 | rna-NM_001178994.3_PE2H3 | cds-NP_011029.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:362907-364835:+ | gene-YER103W_PE2H4 | rna-NM_001178994.3_PE2H4 | cds-NP_011029.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:364589-366517:+ | gene-YER103W_S288C | rna-NM_001178994.3_S288C | cds-NP_011029.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000023.1:74206-76134:+ | gene-YER103W_SA1 | rna-NM_001178994.3_SA1 | cds-NP_011029.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:359592-361520:+ | gene-YER103W_ThermosaccDry | rna-NM_001178994.3_ThermosaccDry | cds-NP_011029.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:360654-362582:+ | gene-YER103W_VR1 | rna-NM_001178994.3_VR1 | cds-NP_011029.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:356721-358649:+ | gene-YER103W_ZTW1 | rna-NM_001178994.3_ZTW1 | cds-NP_011029.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:360631-362559:+ | gene-YER103W_Sparadoxus | rna-NM_001178994.3_Sparadoxus | cds-NP_011029.3_Sparadoxus | 91.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |