Gene name: SSA2
Reference locus (S288C): YLL024C
Gene biotype: protein_coding
Description: Heat shock protein SSA2; HSP70 family ATP-binding protein; involved in protein folding, vacuolar import of proteins; required for ubiquitin-dependent degradation of short-lived proteins; associated with chaperonin-containing T-complex; 98% identical to paralog Ssa1p with distinct functional specificity in propagation of yeast [URE3] prions and vacuolar-mediated degradation of gluconeogenesis enzymes; binds tRNA, has role in tRNA nuclear import during starvation
Top 10 interactors (score): HSP82 (0.999); HSC82 (0.999); STI1 (0.998); SSA1 (0.998); SIS1 (0.998); YDJ1 (0.998); HSF1 (0.995); ZUO1 (0.989); HSP104 (0.984); MDJ1 (0.972); SSE1 (0.971); APJ1 (0.954); XDJ1 (0.935); SKN7 (0.935); FES1 (0.934); HSP60 (0.933); NUP57 (0.927); MLP1 (0.927); HMS2 (0.926); MGA1 (0.926)
Homologues (species, bitscore): HSPA8 (Homo sapiens, 1008.4); Hspa8 (Mus musculus, 1009.2); hspa8 (Danio rerio, 996.9); hspa8 (Xenopus tropicalis, 1003.0); Hsc70-4 (Drosophila melanogaster, 984.9); hsp-1 (Caenorhabditis elegans, 1011.5); HSC70-1 (Arabidopsis thaliana, 945.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:82727-84894:- | gene-YLL024C_AKU4011 | rna-NM_001181844.1_AKU4011 | cds-NP_013076.1_AKU4011 | 77.5 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:46674-48593:- | gene-YLL024C_BG1 | rna-NM_001181844.1_BG1 | cds-NP_013076.1_BG1 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:90425-92593:- | gene-YLL024C_CBS1585 | rna-NM_001181844.1_CBS1585 | cds-NP_013076.1_CBS1585 | 87.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:80624-83041:- | gene-YLL024C_CBS436 | rna-NM_001181844.1_CBS436 | cds-NP_013076.1_CBS436 | 78.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:90342-92079:- | gene-YLL024C_CBS6412 | rna-NM_001181844.1_CBS6412 | cds-NP_013076.1_CBS6412 | 67.4 | 83.6 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:90435-92852:- | gene-YLL024C_CBS6413 | rna-NM_001181844.1_CBS6413 | cds-NP_013076.1_CBS6413 | 78.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:80570-82509:- | gene-YLL024C_CENPK1137D | rna-NM_001181844.1_CENPK1137D | cds-NP_013076.1_CENPK1137D | 98.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:83122-85033:- | gene-YLL024C_EthanolRed | rna-NM_001181844.1_EthanolRed | cds-NP_013076.1_EthanolRed | 97.9 | 99.5 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:82436-84604:- | gene-YLL024C_FaliES1 | rna-NM_001181844.1_FaliES1 | cds-NP_013076.1_FaliES1 | 87.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000166.1:562-1070:- | gene-YLL024C_JAY291 | rna-NM_001181844.1_JAY291 | cds-NP_013076.1_JAY291 | 25.7 | 26.5 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:90393-92810:- | gene-YLL024C_MUCL30387 | rna-NM_001181844.1_MUCL30387 | cds-NP_013076.1_MUCL30387 | 78.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:95121-97039:- | gene-YLL024C_MUCL30388 | rna-NM_001181844.1_MUCL30388 | cds-NP_013076.1_MUCL30388 | 84.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:90634-93051:- | gene-YLL024C_MUCL39482 | rna-NM_001181844.1_MUCL39482 | cds-NP_013076.1_MUCL39482 | 78.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:90730-92648:- | gene-YLL024C_MUCL42920 | rna-NM_001181844.1_MUCL42920 | cds-NP_013076.1_MUCL42920 | 78.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:95540-97459:- | gene-YLL024C_NCIM3186 | rna-NM_001181844.1_NCIM3186 | cds-NP_013076.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:82501-84669:- | gene-YLL024C_NCYC1407 | rna-NM_001181844.1_NCYC1407 | cds-NP_013076.1_NCYC1407 | 87.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:89185-91104:- | gene-YLL024C_PE2H3 | rna-NM_001181844.1_PE2H3 | cds-NP_013076.1_PE2H3 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:88995-90914:- | gene-YLL024C_PE2H4 | rna-NM_001181844.1_PE2H4 | cds-NP_013076.1_PE2H4 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:95566-97485:- | gene-YLL024C_S288C | rna-NM_001181844.1_S288C | cds-NP_013076.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:82942-85110:- | gene-YLL024C_ThermosaccDry | rna-NM_001181844.1_ThermosaccDry | cds-NP_013076.1_ThermosaccDry | 87.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:144718-146637:- | gene-YLL024C_VR1 | rna-NM_001181844.1_VR1 | cds-NP_013076.1_VR1 | 97.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:82510-84429:- | gene-YLL024C_ZTW1 | rna-NM_001181844.1_ZTW1 | cds-NP_013076.1_ZTW1 | 97.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:91007-92926:- | gene-YLL024C_Sparadoxus | rna-NM_001181844.1_Sparadoxus | cds-NP_013076.1_Sparadoxus | 96.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |