Gene name: SSA1
Reference locus (S288C): YAL005C
Gene biotype: protein_coding
Description: Heat shock protein SSA1; ATPase involved in protein folding and NLS-directed nuclear transport; member of HSP70 family; required for ubiquitin-dependent degradation of short-lived proteins; forms chaperone complex with Ydj1p; localized to nucleus, cytoplasm, cell wall; 98% identical to paralog Ssa2p with different functional specificity in propagation of yeast [URE3] prions, vacuolar-mediated degradations of gluconeogenesis enzymes; general targeting factor of Hsp104p to prion fibrils
Top 10 interactors (score): HSC82 (0.999); HSP82 (0.999); SIS1 (0.999); HSP104 (0.999); STI1 (0.999); YDJ1 (0.999); HSF1 (0.998); SSA2 (0.998); SUP35 (0.997); FES1 (0.992); ZUO1 (0.99); SSE1 (0.986); SGT2 (0.969); TOM71 (0.967); APJ1 (0.967); MDJ1 (0.966); URE2 (0.964); XDJ1 (0.961); NUP1 (0.952); NSP1 (0.946)
Homologues (species, bitscore): HSPA8 (Homo sapiens, 1010.4); Hspa8 (Mus musculus, 1011.9); hspa8 (Danio rerio, 1005.7); hspa8 (Xenopus tropicalis, 1006.5); Hsc70-4 (Drosophila melanogaster, 993.8); hsp-1 (Caenorhabditis elegans, 1008.1); HSP70 (Arabidopsis thaliana, 954.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:124612-126858:- | gene-YAL005C_AKU4011 | rna-NM_001178151.1_AKU4011 | cds-NP_009396.2_AKU4011 | 85.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:139486-141663:- | gene-YAL005C_Bruggeman | rna-NM_001178151.1_Bruggeman | cds-NP_009396.2_Bruggeman | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:125822-128248:- | gene-YAL005C_CAT1 | rna-NM_001178151.1_CAT1 | cds-NP_009396.2_CAT1 | 79.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:137627-139554:- | gene-YAL005C_CBS1585 | rna-NM_001178151.1_CBS1585 | cds-NP_009396.2_CBS1585 | 84.0 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:137927-139865:- | gene-YAL005C_CBS436 | rna-NM_001178151.1_CBS436 | cds-NP_009396.2_CBS436 | 63.9 | 98.7 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:750729-752296:- | gene-YAL005C_CBS6412 | rna-NM_001178151.1_CBS6412 | cds-NP_009396.2_CBS6412 | 79.3 | 81.2 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:135897-137824:- | gene-YAL005C_CBS6413 | rna-NM_001178151.1_CBS6413 | cds-NP_009396.2_CBS6413 | 79.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:126034-127416:- | gene-YAL005C_EthanolRed | rna-NM_001178151.1_EthanolRed | cds-NP_009396.2_EthanolRed | 68.7 | 71.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000154.1:1-1004:- | gene-YAL005C_JAY291 | rna-NM_001178151.1_JAY291 | cds-NP_009396.2_JAY291 | 51.7 | 52.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:140639-142566:- | gene-YAL005C_MUCL30387 | rna-NM_001178151.1_MUCL30387 | cds-NP_009396.2_MUCL30387 | 78.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:137887-140064:- | gene-YAL005C_MUCL30388 | rna-NM_001178151.1_MUCL30388 | cds-NP_009396.2_MUCL30388 | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:136903-138830:- | gene-YAL005C_MUCL39482 | rna-NM_001178151.1_MUCL39482 | cds-NP_009396.2_MUCL39482 | 79.3 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:138787-140964:- | gene-YAL005C_MUCL42920 | rna-NM_001178151.1_MUCL42920 | cds-NP_009396.2_MUCL42920 | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:139380-141308:- | gene-YAL005C_NCIM3186 | rna-NM_001178151.1_NCIM3186 | cds-NP_009396.2_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:124292-126219:- | gene-YAL005C_NCYC1407 | rna-NM_001178151.1_NCYC1407 | cds-NP_009396.2_NCYC1407 | 84.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:126217-128145:- | gene-YAL005C_PE2H3 | rna-NM_001178151.1_PE2H3 | cds-NP_009396.2_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:125936-127864:- | gene-YAL005C_PE2H4 | rna-NM_001178151.1_PE2H4 | cds-NP_009396.2_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:139503-141431:- | gene-YAL005C_S288C | rna-NM_001178151.1_S288C | cds-NP_009396.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000178.1:1-1785:+ | gene-YAL005C_SA1 | rna-NM_001178151.1_SA1 | cds-NP_009396.2_SA1 | 92.1 | 92.5 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:141460-143209:- | gene-YAL005C_VR1 | rna-NM_001178151.1_VR1 | cds-NP_009396.2_VR1 | 75.4 | 87.5 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:111976-113904:- | gene-YAL005C_ZTW1 | rna-NM_001178151.1_ZTW1 | cds-NP_009396.2_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:129547-131475:- | gene-YAL005C_Sparadoxus | rna-NM_001178151.1_Sparadoxus | cds-NP_009396.2_Sparadoxus | 95.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |