SRY1 (YKL218C)


Gene profile

Gene name: SRY1
Reference locus (S288C): YKL218C
Gene biotype: protein_coding

Description: Threo-3-hydroxy-L-aspartate ammonia-lyase SRY1; 3-hydroxyaspartate dehydratase; deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required in the presence of hydroxyaspartate; highly similar to mouse serine racemase (Srr) but has no serine racemase activity

Top 10 interactors (score): COS9 (0.892); PRE5 (0.889); TRP3 (0.837); YKL223W (0.78); YHL041W (0.773); YHL048C-A (0.773); YHL046W-A (0.773); YPL257W (0.748); YKL225W (0.747); PAU16 (0.747); ARL3 (0.745); YHL045W (0.745); PAU13 (0.712); MGA1 (0.712); YHL042W (0.698); YKL222C (0.697); UBR2 (0.696); YHL049C (0.691); YHL050C (0.67); YHL044W (0.67)

Homologues (species, bitscore): SRR (Homo sapiens, 244.6); Srr (Mus musculus, 236.1); si:ch73-263o4.4 (Danio rerio, 122.1); srr (Xenopus tropicalis, 233.0); CG8129 (Drosophila melanogaster, 189.9); Y51H7C.9 (Caenorhabditis elegans, 184.1); SR (Arabidopsis thaliana, 254.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:3203-4183:- gene-YKL218C_AKU4011 rna-NM_001179783.1_AKU4011 cds-NP_012704.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000195.1:1135-2115:+ gene-YKL218C_BG1 rna-NM_001179783.1_BG1 cds-NP_012704.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:21126-22106:- gene-YKL218C_Bruggeman rna-NM_001179783.1_Bruggeman cds-NP_012704.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:16019-16999:- gene-YKL218C_CAT1 rna-NM_001179783.1_CAT1 cds-NP_012704.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:15228-16208:- gene-YKL218C_CBS1585 rna-NM_001179783.1_CBS1585 cds-NP_012704.1_CBS1585 99.8 100.0 Unannotated 1 1 0 False False False False True
CBS436 GCA_001738355.1 Sake Asia CM005353.1:14921-15901:- gene-YKL218C_CBS436 rna-NM_001179783.1_CBS436 cds-NP_012704.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:1353-2333:- gene-YKL218C_CBS6412 rna-NM_001179783.1_CBS6412 cds-NP_012704.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:15908-16888:- gene-YKL218C_CBS6413 rna-NM_001179783.1_CBS6413 cds-NP_012704.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:17201-18181:- gene-YKL218C_CENPK1137D rna-NM_001179783.1_CENPK1137D cds-NP_012704.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:15547-16527:- gene-YKL218C_EthanolRed rna-NM_001179783.1_EthanolRed cds-NP_012704.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:15189-16169:- gene-YKL218C_FaliES1 rna-NM_001179783.1_FaliES1 cds-NP_012704.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:14861-15841:- gene-YKL218C_JAY291 rna-NM_001179783.1_JAY291 cds-NP_012704.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:21123-22103:- gene-YKL218C_MUCL30387 rna-NM_001179783.1_MUCL30387 cds-NP_012704.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:16769-17749:- gene-YKL218C_MUCL30388 rna-NM_001179783.1_MUCL30388 cds-NP_012704.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:15272-16252:- gene-YKL218C_MUCL39482 rna-NM_001179783.1_MUCL39482 cds-NP_012704.1_MUCL39482 99.8 100.0 Unannotated 1 1 0 False False False False True
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:19022-20002:- gene-YKL218C_MUCL42920 rna-NM_001179783.1_MUCL42920 cds-NP_012704.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:17348-18328:- gene-YKL218C_NCIM3186 rna-NM_001179783.1_NCIM3186 cds-NP_012704.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:15306-16286:- gene-YKL218C_NCYC1407 rna-NM_001179783.1_NCYC1407 cds-NP_012704.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:23479-24459:- gene-YKL218C_PE2H3 rna-NM_001179783.1_PE2H3 cds-NP_012704.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:19682-20662:- gene-YKL218C_PE2H4 rna-NM_001179783.1_PE2H4 cds-NP_012704.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:17359-18339:- gene-YKL218C_S288C rna-NM_001179783.1_S288C cds-NP_012704.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000167.1:491-1471:- gene-YKL218C_SA1 rna-NM_001179783.1_SA1 cds-NP_012704.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:15926-16906:- gene-YKL218C_ThermosaccDry rna-NM_001179783.1_ThermosaccDry cds-NP_012704.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:15106-16086:- gene-YKL218C_VR1 rna-NM_001179783.1_VR1 cds-NP_012704.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:14892-15872:- gene-YKL218C_ZTW1 rna-NM_001179783.1_ZTW1 cds-NP_012704.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:23457-24437:- gene-YKL218C_Sparadoxus rna-NM_001179783.1_Sparadoxus cds-NP_012704.1_Sparadoxus 88.7 100.0 Verified 1 1 1 False True False False False

Additional files