Gene name: SRX1
Reference locus (S288C): YKL086W
Gene biotype: protein_coding
Description: Sulfiredoxin; contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups in the peroxiredoxin Tsa1p, which is formed upon exposure to oxidants; conserved in higher eukaryotes; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): TSA1 (0.992); TSA2 (0.98); PRX1 (0.921); TRR1 (0.916); TRR2 (0.916); AHP1 (0.905); TRX2 (0.902); TPS1 (0.896); HSP104 (0.896); CTT1 (0.877); DOT5 (0.875); GPX1 (0.847); YAP1 (0.843); TRX1 (0.842); GLR1 (0.835); GPX2 (0.818); CTA1 (0.807); TRX3 (0.779); YML131W (0.768); GTT2 (0.763)
Homologues (species, bitscore): SRXN1 (Homo sapiens, 66.2); Srxn1 (Mus musculus, 65.5); srxn1 (Danio rerio, 65.5); CG6762 (Drosophila melanogaster, 68.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:264840-265223:+ | gene-YKL086W_AKU4011 | rna-NM_001179652.1_AKU4011 | cds-NP_012837.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:242015-242398:+ | gene-YKL086W_BG1 | rna-NM_001179652.1_BG1 | cds-NP_012837.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:283013-283396:+ | gene-YKL086W_Bruggeman | rna-NM_001179652.1_Bruggeman | cds-NP_012837.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:277813-278196:+ | gene-YKL086W_CAT1 | rna-NM_001179652.1_CAT1 | cds-NP_012837.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:277082-277465:+ | gene-YKL086W_CBS1585 | rna-NM_001179652.1_CBS1585 | cds-NP_012837.1_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:275675-276058:+ | gene-YKL086W_CBS436 | rna-NM_001179652.1_CBS436 | cds-NP_012837.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:261710-262093:+ | gene-YKL086W_CBS6412 | rna-NM_001179652.1_CBS6412 | cds-NP_012837.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:277538-277921:+ | gene-YKL086W_CBS6413 | rna-NM_001179652.1_CBS6413 | cds-NP_012837.1_CBS6413 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:277925-278308:+ | gene-YKL086W_CENPK1137D | rna-NM_001179652.1_CENPK1137D | cds-NP_012837.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:275534-275917:+ | gene-YKL086W_EthanolRed | rna-NM_001179652.1_EthanolRed | cds-NP_012837.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:276348-276731:+ | gene-YKL086W_FaliES1 | rna-NM_001179652.1_FaliES1 | cds-NP_012837.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:98677-99060:+ | gene-YKL086W_JAY291 | rna-NM_001179652.1_JAY291 | cds-NP_012837.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:284811-285194:+ | gene-YKL086W_MUCL30387 | rna-NM_001179652.1_MUCL30387 | cds-NP_012837.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:279207-279590:+ | gene-YKL086W_MUCL30388 | rna-NM_001179652.1_MUCL30388 | cds-NP_012837.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:276867-277250:+ | gene-YKL086W_MUCL39482 | rna-NM_001179652.1_MUCL39482 | cds-NP_012837.1_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:281501-281884:+ | gene-YKL086W_MUCL42920 | rna-NM_001179652.1_MUCL42920 | cds-NP_012837.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:278270-278653:+ | gene-YKL086W_NCIM3186 | rna-NM_001179652.1_NCIM3186 | cds-NP_012837.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:277061-277444:+ | gene-YKL086W_NCYC1407 | rna-NM_001179652.1_NCYC1407 | cds-NP_012837.1_NCYC1407 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:284150-284533:+ | gene-YKL086W_PE2H3 | rna-NM_001179652.1_PE2H3 | cds-NP_012837.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:280437-280820:+ | gene-YKL086W_PE2H4 | rna-NM_001179652.1_PE2H4 | cds-NP_012837.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:278281-278664:+ | gene-YKL086W_S288C | rna-NM_001179652.1_S288C | cds-NP_012837.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:194411-194794:+ | gene-YKL086W_SA1 | rna-NM_001179652.1_SA1 | cds-NP_012837.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:277052-277435:+ | gene-YKL086W_ThermosaccDry | rna-NM_001179652.1_ThermosaccDry | cds-NP_012837.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:276412-276795:+ | gene-YKL086W_VR1 | rna-NM_001179652.1_VR1 | cds-NP_012837.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:275616-275999:+ | gene-YKL086W_ZTW1 | rna-NM_001179652.1_ZTW1 | cds-NP_012837.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:292737-293120:+ | gene-YKL086W_Sparadoxus | rna-NM_001179652.1_Sparadoxus | cds-NP_012837.1_Sparadoxus | 93.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |