SRT1 (YMR101C)


Gene profile

Gene name: SRT1
Reference locus (S288C): YMR101C
Gene biotype: protein_coding

Description: Forms the dehydrodolichyl diphosphate syntase (DDS) complex with NUS1; involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase; Belongs to the UPP synthase family

Top 10 interactors (score): NUS1 (0.996); ERG20 (0.993); RAM2 (0.962); RER2 (0.952); RAM1 (0.951); BTS1 (0.951); DPM1 (0.938); COQ1 (0.93); ERG9 (0.915); DFG10 (0.911); YMR103C (0.695); YBR013C (0.695); YBR116C (0.69); SEC59 (0.677); RMA1 (0.647); CAX4 (0.636); MVD1 (0.594); YIR016W (0.591); IDI1 (0.589); OPI10 (0.573)

Homologues (species, bitscore): DHDDS (Homo sapiens, 151.4); Dhdds (Mus musculus, 154.5); dhdds (Danio rerio, 153.3); dhdds (Xenopus tropicalis, 163.3); CG10778 (Drosophila melanogaster, 139.0); T01G1.4 (Caenorhabditis elegans, 162.2); cPT9 (Arabidopsis thaliana, 149.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:506388-507419:- gene-YMR101C_AKU4011 rna-NM_001182601.1_AKU4011 cds-NP_013819.1_AKU4011 99.4 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:35596-36627:+ gene-YMR101C_BG1 rna-NM_001182601.1_BG1 cds-NP_013819.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:448815-449846:- gene-YMR101C_Bruggeman rna-NM_001182601.1_Bruggeman cds-NP_013819.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:449137-450168:- gene-YMR101C_CAT1 rna-NM_001182601.1_CAT1 cds-NP_013819.1_CAT1 99.3 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:439335-440366:- gene-YMR101C_CBS1585 rna-NM_001182601.1_CBS1585 cds-NP_013819.1_CBS1585 99.1 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:444650-445681:- gene-YMR101C_CBS436 rna-NM_001182601.1_CBS436 cds-NP_013819.1_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:552429-553460:- gene-YMR101C_CBS6412 rna-NM_001182601.1_CBS6412 cds-NP_013819.1_CBS6412 99.4 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:438592-439623:- gene-YMR101C_CBS6413 rna-NM_001182601.1_CBS6413 cds-NP_013819.1_CBS6413 99.3 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:462553-463584:- gene-YMR101C_CENPK1137D rna-NM_001182601.1_CENPK1137D cds-NP_013819.1_CENPK1137D 99.0 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:439227-440258:- gene-YMR101C_EthanolRed rna-NM_001182601.1_EthanolRed cds-NP_013819.1_EthanolRed 99.3 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:442392-443423:- gene-YMR101C_FaliES1 rna-NM_001182601.1_FaliES1 cds-NP_013819.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000349.1:5198-6229:- gene-YMR101C_JAY291 rna-NM_001182601.1_JAY291 cds-NP_013819.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:445738-446769:- gene-YMR101C_MUCL30387 rna-NM_001182601.1_MUCL30387 cds-NP_013819.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:449734-450765:- gene-YMR101C_MUCL30388 rna-NM_001182601.1_MUCL30388 cds-NP_013819.1_MUCL30388 99.3 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:439641-440672:- gene-YMR101C_MUCL39482 rna-NM_001182601.1_MUCL39482 cds-NP_013819.1_MUCL39482 99.2 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:446304-447335:- gene-YMR101C_MUCL42920 rna-NM_001182601.1_MUCL42920 cds-NP_013819.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:468399-469430:- gene-YMR101C_NCIM3186 rna-NM_001182601.1_NCIM3186 cds-NP_013819.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:439536-440567:- gene-YMR101C_NCYC1407 rna-NM_001182601.1_NCYC1407 cds-NP_013819.1_NCYC1407 99.3 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:445248-446279:- gene-YMR101C_PE2H3 rna-NM_001182601.1_PE2H3 cds-NP_013819.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:451343-452374:- gene-YMR101C_PE2H4 rna-NM_001182601.1_PE2H4 cds-NP_013819.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:468445-469476:- gene-YMR101C_S288C rna-NM_001182601.1_S288C cds-NP_013819.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:80690-81721:+ gene-YMR101C_SA1 rna-NM_001182601.1_SA1 cds-NP_013819.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:440195-441226:- gene-YMR101C_ThermosaccDry rna-NM_001182601.1_ThermosaccDry cds-NP_013819.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:451834-452865:- gene-YMR101C_VR1 rna-NM_001182601.1_VR1 cds-NP_013819.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:416464-417496:- gene-YMR101C_ZTW1 rna-NM_001182601.1_ZTW1 cds-NP_013819.1_ZTW1 99.4 100.0 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:452724-453758:- gene-YMR101C_Sparadoxus rna-NM_001182601.1_Sparadoxus cds-NP_013819.1_Sparadoxus 88.5 99.8 Verified 1 1 1 False True False False False

Additional files