Gene name: SRS2
Reference locus (S288C): YJL092W
Gene biotype: protein_coding
Description: DNA helicase and DNA-dependent ATPase; involved in DNA repair and checkpoint recovery, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; blocks trinucleotide repeat expansion; affects genome stability; disassembles Rad51p nucleoprotein filaments during meiotic recombination; stimulates activity of the Mus81p-Mms4p endonuclease, independently of Srs2p catalytic activity; functional homolog of human RTEL1
Top 10 interactors (score): SGS1 (0.999); RAD52 (0.999); RAD51 (0.999); SMT3 (0.999); RAD57 (0.998); RAD54 (0.998); POL30 (0.998); MUS81 (0.997); RAD5 (0.997); MPH1 (0.996); TOP3 (0.993); RRM3 (0.993); RAD6 (0.993); RAD18 (0.992); RAD55 (0.99); ELG1 (0.988); EXO1 (0.986); RTT107 (0.984); MRC1 (0.984); RMI1 (0.982)
Homologues (species, bitscore): SRS2 (Arabidopsis thaliana, 156.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:240143-243667:+ | gene-YJL092W_AKU4011 | rna-NM_001181525.1_AKU4011 | cds-NP_012443.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:370786-374310:- | gene-YJL092W_BG1 | rna-NM_001181525.1_BG1 | cds-NP_012443.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:251588-255112:+ | gene-YJL092W_Bruggeman | rna-NM_001181525.1_Bruggeman | cds-NP_012443.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:256485-260009:+ | gene-YJL092W_CAT1 | rna-NM_001181525.1_CAT1 | cds-NP_012443.1_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:251804-255328:+ | gene-YJL092W_CBS1585 | rna-NM_001181525.1_CBS1585 | cds-NP_012443.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:269912-273436:+ | gene-YJL092W_CBS436 | rna-NM_001181525.1_CBS436 | cds-NP_012443.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:240901-244425:+ | gene-YJL092W_CBS6412 | rna-NM_001181525.1_CBS6412 | cds-NP_012443.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:242256-245780:+ | gene-YJL092W_CBS6413 | rna-NM_001181525.1_CBS6413 | cds-NP_012443.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:239894-243418:+ | gene-YJL092W_CENPK1137D | rna-NM_001181525.1_CENPK1137D | cds-NP_012443.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:243990-247514:+ | gene-YJL092W_EthanolRed | rna-NM_001181525.1_EthanolRed | cds-NP_012443.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:255567-259091:+ | gene-YJL092W_FaliES1 | rna-NM_001181525.1_FaliES1 | cds-NP_012443.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000138.1:53184-56708:+ | gene-YJL092W_JAY291 | rna-NM_001181525.1_JAY291 | cds-NP_012443.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:253858-257382:+ | gene-YJL092W_MUCL30387 | rna-NM_001181525.1_MUCL30387 | cds-NP_012443.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:249933-253457:+ | gene-YJL092W_MUCL30388 | rna-NM_001181525.1_MUCL30388 | cds-NP_012443.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:244561-248085:+ | gene-YJL092W_MUCL39482 | rna-NM_001181525.1_MUCL39482 | cds-NP_012443.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:250766-254290:+ | gene-YJL092W_MUCL42920 | rna-NM_001181525.1_MUCL42920 | cds-NP_012443.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:257402-260926:+ | gene-YJL092W_NCIM3186 | rna-NM_001181525.1_NCIM3186 | cds-NP_012443.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:243249-246773:+ | gene-YJL092W_NCYC1407 | rna-NM_001181525.1_NCYC1407 | cds-NP_012443.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:255610-259134:+ | gene-YJL092W_PE2H3 | rna-NM_001181525.1_PE2H3 | cds-NP_012443.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:255254-258778:+ | gene-YJL092W_PE2H4 | rna-NM_001181525.1_PE2H4 | cds-NP_012443.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:257423-260947:+ | gene-YJL092W_S288C | rna-NM_001181525.1_S288C | cds-NP_012443.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:53126-56650:+ | gene-YJL092W_SA1 | rna-NM_001181525.1_SA1 | cds-NP_012443.1_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:248976-252500:+ | gene-YJL092W_ThermosaccDry | rna-NM_001181525.1_ThermosaccDry | cds-NP_012443.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:250486-254010:+ | gene-YJL092W_VR1 | rna-NM_001181525.1_VR1 | cds-NP_012443.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:230337-233861:+ | gene-YJL092W_ZTW1 | rna-NM_001181525.1_ZTW1 | cds-NP_012443.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:254423-257953:+ | gene-YJL092W_Sparadoxus | rna-NM_001181525.1_Sparadoxus | cds-NP_012443.1_Sparadoxus | 88.5 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |