SRP68 (YPL243W)


Gene profile

Gene name: SRP68
Reference locus (S288C): YPL243W
Gene biotype: protein_coding

Description: Core component of the signal recognition particle (SRP) complex; SRP complex functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane; relocalizes from cytoplasm to the nuclear periphery upon DNA replication stress; Belongs to the SRP68 family

Top 10 interactors (score): SRP54 (0.999); SRP14 (0.999); SRP72 (0.999); SEC65 (0.999); SRP21 (0.995); SRP102 (0.973); SRP101 (0.972); SRP1 (0.877); RPL5 (0.83); RPL25 (0.83); RPL39 (0.828); RPL30 (0.828); RPL28 (0.828); RPL3 (0.826); RPL38 (0.818); LHP1 (0.818); RPP0 (0.807); RPL29 (0.806); RPL24A (0.804); RPL24B (0.804)

Homologues (species, bitscore): SRP68 (Homo sapiens, 58.2); Srp68 (Mus musculus, 57.4); F55C5.8 (Caenorhabditis elegans, 52.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:66265-68064:+ gene-YPL243W_AKU4011 rna-NM_001184057.1_AKU4011 cds-NP_015081.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000184.1:7079-8878:- gene-YPL243W_BG1 rna-NM_001184057.1_BG1 cds-NP_015081.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:90149-91948:+ gene-YPL243W_Bruggeman rna-NM_001184057.1_Bruggeman cds-NP_015081.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:88264-90063:+ gene-YPL243W_CAT1 rna-NM_001184057.1_CAT1 cds-NP_015081.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:70578-72377:+ gene-YPL243W_CBS1585 rna-NM_001184057.1_CBS1585 cds-NP_015081.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:84999-86798:+ gene-YPL243W_CBS436 rna-NM_001184057.1_CBS436 cds-NP_015081.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:75742-77541:+ gene-YPL243W_CBS6412 rna-NM_001184057.1_CBS6412 cds-NP_015081.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:66728-68527:+ gene-YPL243W_CBS6413 rna-NM_001184057.1_CBS6413 cds-NP_015081.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:88452-90251:+ gene-YPL243W_CENPK1137D rna-NM_001184057.1_CENPK1137D cds-NP_015081.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:65665-67464:+ gene-YPL243W_EthanolRed rna-NM_001184057.1_EthanolRed cds-NP_015081.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:72472-74271:+ gene-YPL243W_FaliES1 rna-NM_001184057.1_FaliES1 cds-NP_015081.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000264.1:6479-8278:- gene-YPL243W_JAY291 rna-NM_001184057.1_JAY291 cds-NP_015081.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:83307-85106:+ gene-YPL243W_MUCL30387 rna-NM_001184057.1_MUCL30387 cds-NP_015081.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:81750-83549:+ gene-YPL243W_MUCL30388 rna-NM_001184057.1_MUCL30388 cds-NP_015081.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:63708-65507:+ gene-YPL243W_MUCL39482 rna-NM_001184057.1_MUCL39482 cds-NP_015081.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:82576-84375:+ gene-YPL243W_MUCL42920 rna-NM_001184057.1_MUCL42920 cds-NP_015081.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:88500-90299:+ gene-YPL243W_NCIM3186 rna-NM_001184057.1_NCIM3186 cds-NP_015081.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:70155-71954:+ gene-YPL243W_NCYC1407 rna-NM_001184057.1_NCYC1407 cds-NP_015081.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:77879-79678:+ gene-YPL243W_PE2H3 rna-NM_001184057.1_PE2H3 cds-NP_015081.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:77522-79321:+ gene-YPL243W_PE2H4 rna-NM_001184057.1_PE2H4 cds-NP_015081.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:88517-90316:+ gene-YPL243W_S288C rna-NM_001184057.1_S288C cds-NP_015081.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000056.1:30395-32194:+ gene-YPL243W_SA1 rna-NM_001184057.1_SA1 cds-NP_015081.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:72473-74272:+ gene-YPL243W_ThermosaccDry rna-NM_001184057.1_ThermosaccDry cds-NP_015081.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:312348-314147:+ gene-YPL243W_VR1 rna-NM_001184057.1_VR1 cds-NP_015081.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:72017-73816:+ gene-YPL243W_ZTW1 rna-NM_001184057.1_ZTW1 cds-NP_015081.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:73574-75373:+ gene-YPL243W_Sparadoxus rna-NM_001184057.1_Sparadoxus cds-NP_015081.1_Sparadoxus 90.1 100.0 Verified 1 1 1 False True False False False

Additional files