Gene name: SRO77
Reference locus (S288C): YBL106C
Gene biotype: protein_coding
Description: Lethal(2) giant larvae protein homolog SRO77; Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; regulates cell proliferation and colony development via the Rho1-Tor1 pathway; interacts with SNARE protein Sec9p; homolog of Drosophila lethal giant larvae tumor suppressor; SRO77 has a paralog, SRO7, that arose from the whole genome duplication
Top 10 interactors (score): SEC9 (0.942); SSO1 (0.886); EXO84 (0.884); MYO1 (0.881); RHO3 (0.833); SEC8 (0.797); SRO7 (0.781); SSO2 (0.764); NIP100 (0.747); SEC4 (0.739); SEC15 (0.704); YIP1 (0.696); APP1 (0.696); MYO2 (0.677); MCA1 (0.676); SEC10 (0.661); YHR045W (0.658); VTI1 (0.646); SEC22 (0.621); SEC5 (0.597)
Homologues (species, bitscore): STXBP5L (Homo sapiens, 73.6); Stxbp5l (Mus musculus, 71.6); stxbp5b (Danio rerio, 70.1); STXBP5 (Xenopus tropicalis, 53.5); Tomosyn (Drosophila melanogaster, 63.2); tom-1 (Caenorhabditis elegans, 50.8); AT5G05570 (Arabidopsis thaliana, 58.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:10746-13778:- | gene-YBL106C_AKU4011 | rna-NM_001178346.2_AKU4011 | cds-NP_009444.2_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:1468-4500:- | gene-YBL106C_BG1 | rna-NM_001178346.2_BG1 | cds-NP_009444.2_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:11130-14162:- | gene-YBL106C_Bruggeman | rna-NM_001178346.2_Bruggeman | cds-NP_009444.2_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:13334-16366:- | gene-YBL106C_CAT1 | rna-NM_001178346.2_CAT1 | cds-NP_009444.2_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:2817-5849:- | gene-YBL106C_CBS1585 | rna-NM_001178346.2_CBS1585 | cds-NP_009444.2_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:5767-8799:- | gene-YBL106C_CBS436 | rna-NM_001178346.2_CBS436 | cds-NP_009444.2_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:2605-5637:- | gene-YBL106C_CBS6412 | rna-NM_001178346.2_CBS6412 | cds-NP_009444.2_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:8947-11979:- | gene-YBL106C_CBS6413 | rna-NM_001178346.2_CBS6413 | cds-NP_009444.2_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:4779-7811:- | gene-YBL106C_CENPK1137D | rna-NM_001178346.2_CENPK1137D | cds-NP_009444.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:24987-28019:- | gene-YBL106C_EthanolRed | rna-NM_001178346.2_EthanolRed | cds-NP_009444.2_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:25119-28151:- | gene-YBL106C_FaliES1 | rna-NM_001178346.2_FaliES1 | cds-NP_009444.2_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000184.1:2161-5193:- | gene-YBL106C_JAY291 | rna-NM_001178346.2_JAY291 | cds-NP_009444.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:10271-13303:- | gene-YBL106C_MUCL30387 | rna-NM_001178346.2_MUCL30387 | cds-NP_009444.2_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:10375-13407:- | gene-YBL106C_MUCL30388 | rna-NM_001178346.2_MUCL30388 | cds-NP_009444.2_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:2973-6005:- | gene-YBL106C_MUCL39482 | rna-NM_001178346.2_MUCL39482 | cds-NP_009444.2_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:9612-12644:- | gene-YBL106C_MUCL42920 | rna-NM_001178346.2_MUCL42920 | cds-NP_009444.2_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:10644-13676:- | gene-YBL106C_NCIM3186 | rna-NM_001178346.2_NCIM3186 | cds-NP_009444.2_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:4645-7677:- | gene-YBL106C_NCYC1407 | rna-NM_001178346.2_NCYC1407 | cds-NP_009444.2_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:10951-13983:- | gene-YBL106C_PE2H3 | rna-NM_001178346.2_PE2H3 | cds-NP_009444.2_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:8583-11615:- | gene-YBL106C_PE2H4 | rna-NM_001178346.2_PE2H4 | cds-NP_009444.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:10847-13879:- | gene-YBL106C_S288C | rna-NM_001178346.2_S288C | cds-NP_009444.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:1266-4298:- | gene-YBL106C_SA1 | rna-NM_001178346.2_SA1 | cds-NP_009444.2_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:25081-28113:- | gene-YBL106C_ThermosaccDry | rna-NM_001178346.2_ThermosaccDry | cds-NP_009444.2_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:7296-10328:- | gene-YBL106C_VR1 | rna-NM_001178346.2_VR1 | cds-NP_009444.2_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:2306-5339:- | gene-YBL106C_ZTW1 | rna-NM_001178346.2_ZTW1 | cds-NP_009444.2_ZTW1 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:37244-40276:- | gene-YBL106C_Sparadoxus | rna-NM_001178346.2_Sparadoxus | cds-NP_009444.2_Sparadoxus | 88.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |