Gene name: SRO7
Reference locus (S288C): YPR032W
Gene biotype: protein_coding
Description: Lethal(2) giant larvae protein homolog SRO7; Effector of Rab GTPase Sec4p; forms a complex with Sec4p and t-SNARE Sec9p; involved in exocytosis and docking and fusion of post-Golgi vesicles with plasma membrane; regulates cell proliferation and colony development via the Rho1-Tor1 pathway; homolog of Drosophila lgl tumor suppressor; SRO7 has a paralog, SRO77, that arose from the whole genome duplication; Belongs to the WD repeat L(2)GL family
Top 10 interactors (score): SEC9 (0.998); SEC4 (0.992); EXO84 (0.99); SSO1 (0.979); MYO2 (0.976); SEC15 (0.964); SEC8 (0.962); RHO3 (0.939); SEC3 (0.926); SEC10 (0.914); EXO70 (0.913); SSO2 (0.913); SNC1 (0.878); CDC42 (0.849); SEC1 (0.844); SEC5 (0.82); SEC6 (0.815); SEC2 (0.784); SRO77 (0.781); SHE2 (0.75)
Homologues (species, bitscore): STXBP5L (Homo sapiens, 93.6); Stxbp5l (Mus musculus, 85.5); stxbp5a (Danio rerio, 79.3); STXBP5L (Xenopus tropicalis, 60.8); Tomosyn (Drosophila melanogaster, 74.7); tom-1 (Caenorhabditis elegans, 53.9); DAW1 (Arabidopsis thaliana, 51.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:605780-608881:+ | gene-YPR032W_AKU4011 | rna-NM_001184129.1_AKU4011 | cds-NP_015357.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:288781-291882:- | gene-YPR032W_BG1 | rna-NM_001184129.1_BG1 | cds-NP_015357.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:683441-686542:+ | gene-YPR032W_Bruggeman | rna-NM_001184129.1_Bruggeman | cds-NP_015357.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:726412-729513:+ | gene-YPR032W_CAT1 | rna-NM_001184129.1_CAT1 | cds-NP_015357.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:609464-612565:+ | gene-YPR032W_CBS1585 | rna-NM_001184129.1_CBS1585 | cds-NP_015357.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:623852-626953:+ | gene-YPR032W_CBS436 | rna-NM_001184129.1_CBS436 | cds-NP_015357.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:613212-616313:+ | gene-YPR032W_CBS6412 | rna-NM_001184129.1_CBS6412 | cds-NP_015357.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:606411-609512:+ | gene-YPR032W_CBS6413 | rna-NM_001184129.1_CBS6413 | cds-NP_015357.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:634100-637201:+ | gene-YPR032W_CENPK1137D | rna-NM_001184129.1_CENPK1137D | cds-NP_015357.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:603710-606811:+ | gene-YPR032W_EthanolRed | rna-NM_001184129.1_EthanolRed | cds-NP_015357.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:611513-614614:+ | gene-YPR032W_FaliES1 | rna-NM_001184129.1_FaliES1 | cds-NP_015357.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000116.1:13281-16382:- | gene-YPR032W_JAY291 | rna-NM_001184129.1_JAY291 | cds-NP_015357.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:624653-627754:+ | gene-YPR032W_MUCL30387 | rna-NM_001184129.1_MUCL30387 | cds-NP_015357.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:623334-626435:+ | gene-YPR032W_MUCL30388 | rna-NM_001184129.1_MUCL30388 | cds-NP_015357.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:602721-605822:+ | gene-YPR032W_MUCL39482 | rna-NM_001184129.1_MUCL39482 | cds-NP_015357.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:665531-668632:+ | gene-YPR032W_MUCL42920 | rna-NM_001184129.1_MUCL42920 | cds-NP_015357.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:634106-637207:+ | gene-YPR032W_NCIM3186 | rna-NM_001184129.1_NCIM3186 | cds-NP_015357.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:610652-613753:+ | gene-YPR032W_NCYC1407 | rna-NM_001184129.1_NCYC1407 | cds-NP_015357.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:616884-619985:+ | gene-YPR032W_PE2H3 | rna-NM_001184129.1_PE2H3 | cds-NP_015357.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:616532-619633:+ | gene-YPR032W_PE2H4 | rna-NM_001184129.1_PE2H4 | cds-NP_015357.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:634123-637224:+ | gene-YPR032W_S288C | rna-NM_001184129.1_S288C | cds-NP_015357.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:63551-66652:- | gene-YPR032W_SA1 | rna-NM_001184129.1_SA1 | cds-NP_015357.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:611313-614414:+ | gene-YPR032W_ThermosaccDry | rna-NM_001184129.1_ThermosaccDry | cds-NP_015357.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:627545-630646:+ | gene-YPR032W_VR1 | rna-NM_001184129.1_VR1 | cds-NP_015357.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:610633-613734:+ | gene-YPR032W_ZTW1 | rna-NM_001184129.1_ZTW1 | cds-NP_015357.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:611429-614530:+ | gene-YPR032W_Sparadoxus | rna-NM_001184129.1_Sparadoxus | cds-NP_015357.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |