Gene name: SRC1
Reference locus (S288C): YML034W
Gene biotype: protein_coding
Description: Inner nuclear membrane protein; highly enriched at telomeres and subtelomeric regions; functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; alternative splicing of SRC1 pre-mRNA is promoted by Hub1p; mutant has aneuploidy tolerance; SEC1 has a paralog, HEH2, that arose from the whole genome duplication
Top 10 interactors (score): NUR1 (0.986); LRS4 (0.984); SRP1 (0.97); NUP60 (0.931); MPS3 (0.921); POM152 (0.919); CHM7 (0.918); APQ12 (0.878); CSM1 (0.838); DSF1 (0.818); SIR2 (0.815); ESC1 (0.814); MAN2 (0.813); TOF2 (0.776); LAP2 (0.76); POM34 (0.745); SIR4 (0.735); HTZ1 (0.733); SWR1 (0.728); ASI1 (0.717)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:259133-261748:+ | gene-YML034W_AKU4011 | rna-NM_001182391.1_AKU4011 | cds-NP_013679.1_AKU4011 | 98.9 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:281122-283752:- | gene-YML034W_BG1 | rna-NM_001182391.1_BG1 | cds-NP_013679.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:199039-201702:+ | gene-YML034W_Bruggeman | rna-NM_001182391.1_Bruggeman | cds-NP_013679.1_Bruggeman | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:201586-204216:+ | gene-YML034W_CAT1 | rna-NM_001182391.1_CAT1 | cds-NP_013679.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:192088-194697:+ | gene-YML034W_CBS1585 | rna-NM_001182391.1_CBS1585 | cds-NP_013679.1_CBS1585 | 98.7 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:197606-200236:+ | gene-YML034W_CBS436 | rna-NM_001182391.1_CBS436 | cds-NP_013679.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:305821-308436:+ | gene-YML034W_CBS6412 | rna-NM_001182391.1_CBS6412 | cds-NP_013679.1_CBS6412 | 99.0 | 99.4 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:191340-193955:+ | gene-YML034W_CBS6413 | rna-NM_001182391.1_CBS6413 | cds-NP_013679.1_CBS6413 | 99.0 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:204044-206677:+ | gene-YML034W_CENPK1137D | rna-NM_001182391.1_CENPK1137D | cds-NP_013679.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:192091-194724:+ | gene-YML034W_EthanolRed | rna-NM_001182391.1_EthanolRed | cds-NP_013679.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:195055-197688:+ | gene-YML034W_FaliES1 | rna-NM_001182391.1_FaliES1 | cds-NP_013679.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000237.1:14449-17080:- | gene-YML034W_JAY291 | rna-NM_001182391.1_JAY291 | cds-NP_013679.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:196772-199435:+ | gene-YML034W_MUCL30387 | rna-NM_001182391.1_MUCL30387 | cds-NP_013679.1_MUCL30387 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:200783-203412:+ | gene-YML034W_MUCL30388 | rna-NM_001182391.1_MUCL30388 | cds-NP_013679.1_MUCL30388 | 97.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:192368-194983:+ | gene-YML034W_MUCL39482 | rna-NM_001182391.1_MUCL39482 | cds-NP_013679.1_MUCL39482 | 99.0 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:197877-200541:+ | gene-YML034W_MUCL42920 | rna-NM_001182391.1_MUCL42920 | cds-NP_013679.1_MUCL42920 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:209479-212109:+ | gene-YML034W_NCIM3186 | rna-NM_001182391.1_NCIM3186 | cds-NP_013679.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:192311-194926:+ | gene-YML034W_NCYC1407 | rna-NM_001182391.1_NCYC1407 | cds-NP_013679.1_NCYC1407 | 98.9 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:198197-200827:+ | gene-YML034W_PE2H3 | rna-NM_001182391.1_PE2H3 | cds-NP_013679.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:204292-206922:+ | gene-YML034W_PE2H4 | rna-NM_001182391.1_PE2H4 | cds-NP_013679.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:209525-212155:+ | gene-YML034W_S288C | rna-NM_001182391.1_S288C | cds-NP_013679.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000088.1:26694-29324:- | gene-YML034W_SA1 | rna-NM_001182391.1_SA1 | cds-NP_013679.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:192128-194761:+ | gene-YML034W_ThermosaccDry | rna-NM_001182391.1_ThermosaccDry | cds-NP_013679.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:196138-198768:+ | gene-YML034W_VR1 | rna-NM_001182391.1_VR1 | cds-NP_013679.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:171200-173814:+ | gene-YML034W_ZTW1 | rna-NM_001182391.1_ZTW1 | cds-NP_013679.1_ZTW1 | 99.0 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:202933-205559:+ | gene-YML034W_Sparadoxus | rna-NM_001182391.1_Sparadoxus | cds-NP_013679.1_Sparadoxus | 85.6 | 98.6 | Verified | 1 | 1 | 0 | False | False | False | True | False |