SRB8 (YCR081W)


Gene profile

Gene name: SRB8
Reference locus (S288C): YCR081W
Gene biotype: protein_coding

Description: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression

Top 10 interactors (score): SSN3 (0.999); SSN8 (0.999); SSN2 (0.999); SIN4 (0.995); NUT1 (0.989); MED7 (0.988); MED2 (0.986); SOH1 (0.975); ROX3 (0.966); RGR1 (0.964); SRB7 (0.952); GAL11 (0.941); AHC2 (0.918); SRB5 (0.861); SRB6 (0.856); PGD1 (0.846); CSE2 (0.839); MED8 (0.826); SRB2 (0.815); SRB4 (0.789)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:248872-253155:+ gene-YCR081W_AKU4011 rna-NM_001178787.1_AKU4011 cds-NP_010004.1_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000067.1:107528-111811:+ gene-YCR081W_BG1 rna-NM_001178787.1_BG1 cds-NP_010004.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:245083-249366:+ gene-YCR081W_Bruggeman rna-NM_001178787.1_Bruggeman cds-NP_010004.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:256133-260416:+ gene-YCR081W_CAT1 rna-NM_001178787.1_CAT1 cds-NP_010004.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:243687-247970:+ gene-YCR081W_CBS1585 rna-NM_001178787.1_CBS1585 cds-NP_010004.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:255468-259751:+ gene-YCR081W_CBS436 rna-NM_001178787.1_CBS436 cds-NP_010004.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:235389-239672:+ gene-YCR081W_CBS6412 rna-NM_001178787.1_CBS6412 cds-NP_010004.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:249737-254020:+ gene-YCR081W_CBS6413 rna-NM_001178787.1_CBS6413 cds-NP_010004.1_CBS6413 99.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:253568-257851:+ gene-YCR081W_CENPK1137D rna-NM_001178787.1_CENPK1137D cds-NP_010004.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:244687-248970:+ gene-YCR081W_EthanolRed rna-NM_001178787.1_EthanolRed cds-NP_010004.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:250050-254333:+ gene-YCR081W_FaliES1 rna-NM_001178787.1_FaliES1 cds-NP_010004.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000323.1:34457-38740:- gene-YCR081W_JAY291 rna-NM_001178787.1_JAY291 cds-NP_010004.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:242211-246494:+ gene-YCR081W_MUCL30387 rna-NM_001178787.1_MUCL30387 cds-NP_010004.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:242078-246361:+ gene-YCR081W_MUCL30388 rna-NM_001178787.1_MUCL30388 cds-NP_010004.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:250251-254534:+ gene-YCR081W_MUCL39482 rna-NM_001178787.1_MUCL39482 cds-NP_010004.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:246657-250940:+ gene-YCR081W_MUCL42920 rna-NM_001178787.1_MUCL42920 cds-NP_010004.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:254003-258286:+ gene-YCR081W_NCIM3186 rna-NM_001178787.1_NCIM3186 cds-NP_010004.1_NCIM3186 97.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:251090-255373:+ gene-YCR081W_NCYC1407 rna-NM_001178787.1_NCYC1407 cds-NP_010004.1_NCYC1407 99.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:265645-269928:+ gene-YCR081W_PE2H3 rna-NM_001178787.1_PE2H3 cds-NP_010004.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:254199-258482:+ gene-YCR081W_PE2H4 rna-NM_001178787.1_PE2H4 cds-NP_010004.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:254371-258654:+ gene-YCR081W_S288C rna-NM_001178787.1_S288C cds-NP_010004.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000044.1:54220-58503:+ gene-YCR081W_SA1 rna-NM_001178787.1_SA1 cds-NP_010004.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:249977-254260:+ gene-YCR081W_ThermosaccDry rna-NM_001178787.1_ThermosaccDry cds-NP_010004.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:261187-265470:+ gene-YCR081W_VR1 rna-NM_001178787.1_VR1 cds-NP_010004.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:247832-252115:+ gene-YCR081W_ZTW1 rna-NM_001178787.1_ZTW1 cds-NP_010004.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:281970-286262:+ gene-YCR081W_Sparadoxus rna-NM_001178787.1_Sparadoxus cds-NP_010004.1_Sparadoxus 89.5 99.9 Verified 1 1 1 False True False False False

Additional files