Gene name: SQS1
Reference locus (S288C): YNL224C
Gene biotype: protein_coding
Description: Protein that stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles; relocalizes from nucleus to nucleolus upon DNA replication stress; Belongs to the SQS1 family
Top 10 interactors (score): PRP43 (0.999); KRR1 (0.999); UTP30 (0.995); ENP1 (0.994); UTP6 (0.994); UTP22 (0.994); PXR1 (0.993); RRP36 (0.992); NOP19 (0.992); HAS1 (0.992); NOP14 (0.991); IMP3 (0.991); SLX9 (0.991); NOB1 (0.985); LTV1 (0.982); ROK1 (0.975); DHR2 (0.975); YTM1 (0.967); DRS1 (0.966); HCA4 (0.963)
Homologues (species, bitscore): AGGF1 (Homo sapiens, 52.0); Aggf1 (Mus musculus, 52.4); aggf1 (Danio rerio, 59.3); aggf1 (Xenopus tropicalis, 53.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:218576-220879:- | gene-YNL224C_AKU4011 | rna-NM_001183062.1_AKU4011 | cds-NP_014175.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:122519-124822:- | gene-YNL224C_BG1 | rna-NM_001183062.1_BG1 | cds-NP_014175.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:228625-230928:- | gene-YNL224C_Bruggeman | rna-NM_001183062.1_Bruggeman | cds-NP_014175.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:235781-238084:- | gene-YNL224C_CAT1 | rna-NM_001183062.1_CAT1 | cds-NP_014175.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:218973-221276:- | gene-YNL224C_CBS1585 | rna-NM_001183062.1_CBS1585 | cds-NP_014175.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:214056-216359:- | gene-YNL224C_CBS436 | rna-NM_001183062.1_CBS436 | cds-NP_014175.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:215007-217310:- | gene-YNL224C_CBS6412 | rna-NM_001183062.1_CBS6412 | cds-NP_014175.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:215655-217958:- | gene-YNL224C_CBS6413 | rna-NM_001183062.1_CBS6413 | cds-NP_014175.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:218599-220902:- | gene-YNL224C_CENPK1137D | rna-NM_001183062.1_CENPK1137D | cds-NP_014175.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:216226-218514:- | gene-YNL224C_EthanolRed | rna-NM_001183062.1_EthanolRed | cds-NP_014175.1_EthanolRed | 98.8 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:210968-213256:- | gene-YNL224C_FaliES1 | rna-NM_001183062.1_FaliES1 | cds-NP_014175.1_FaliES1 | 98.8 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:122110-124412:- | gene-YNL224C_JAY291 | rna-NM_001183062.1_JAY291 | cds-NP_014175.1_JAY291 | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:224161-226464:- | gene-YNL224C_MUCL30387 | rna-NM_001183062.1_MUCL30387 | cds-NP_014175.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:222744-225047:- | gene-YNL224C_MUCL30388 | rna-NM_001183062.1_MUCL30388 | cds-NP_014175.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:216463-218766:- | gene-YNL224C_MUCL39482 | rna-NM_001183062.1_MUCL39482 | cds-NP_014175.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:218717-221020:- | gene-YNL224C_MUCL42920 | rna-NM_001183062.1_MUCL42920 | cds-NP_014175.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:224765-227068:- | gene-YNL224C_NCIM3186 | rna-NM_001183062.1_NCIM3186 | cds-NP_014175.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:218555-220858:- | gene-YNL224C_NCYC1407 | rna-NM_001183062.1_NCYC1407 | cds-NP_014175.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:215454-217757:- | gene-YNL224C_PE2H3 | rna-NM_001183062.1_PE2H3 | cds-NP_014175.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:214842-217145:- | gene-YNL224C_PE2H4 | rna-NM_001183062.1_PE2H4 | cds-NP_014175.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:224796-227099:- | gene-YNL224C_S288C | rna-NM_001183062.1_S288C | cds-NP_014175.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:25205-27508:+ | gene-YNL224C_SA1 | rna-NM_001183062.1_SA1 | cds-NP_014175.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:211824-214112:- | gene-YNL224C_ThermosaccDry | rna-NM_001183062.1_ThermosaccDry | cds-NP_014175.1_ThermosaccDry | 98.8 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:230810-233113:- | gene-YNL224C_VR1 | rna-NM_001183062.1_VR1 | cds-NP_014175.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:122141-124444:- | gene-YNL224C_ZTW1 | rna-NM_001183062.1_ZTW1 | cds-NP_014175.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:222193-224511:- | gene-YNL224C_Sparadoxus | rna-NM_001183062.1_Sparadoxus | cds-NP_014175.1_Sparadoxus | 84.2 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |