Gene name: SPT6
Reference locus (S288C): YGR116W
Gene biotype: protein_coding
Description: Chromatin-remodeling histone chaperone spt6; Transcription elongation factor SPT6; Nucleosome remodeling protein; functions in various aspects of transcription, chromatin maintenance, and RNA processing; required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region; required for H3K36 trimethylation but not dimethylation by Set2p
Top 10 interactors (score): RPO21 (0.999); SPN1 (0.999); CHD1 (0.999); SPT5 (0.999); SPT4 (0.999); SPT16 (0.999); POB3 (0.999); CTR9 (0.997); SET2 (0.996); DST1 (0.994); RPB3 (0.994); HHT1 (0.993); RTF1 (0.989); CDC73 (0.985); RPB5 (0.984); SNF2 (0.983); LEO1 (0.982); UFD4 (0.975); RPB2 (0.972); STH1 (0.971)
Homologues (species, bitscore): SUPT6H (Homo sapiens, 406.8); Supt6 (Mus musculus, 401.4); supt6h (Danio rerio, 397.1); supt6h (Xenopus tropicalis, 401.7); Spt6 (Drosophila melanogaster, 334.0); emb-5 (Caenorhabditis elegans, 306.2); GTB1 (Arabidopsis thaliana, 306.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:699748-704103:+ | gene-YGR116W_AKU4011 | rna-NM_001181245.1_AKU4011 | cds-NP_011631.1_AKU4011 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000188.1:8198-12553:+ | gene-YGR116W_BG1 | rna-NM_001181245.1_BG1 | cds-NP_011631.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:701412-705767:+ | gene-YGR116W_Bruggeman | rna-NM_001181245.1_Bruggeman | cds-NP_011631.1_Bruggeman | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:699617-703972:+ | gene-YGR116W_CAT1 | rna-NM_001181245.1_CAT1 | cds-NP_011631.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:700738-705093:+ | gene-YGR116W_CBS1585 | rna-NM_001181245.1_CBS1585 | cds-NP_011631.1_CBS1585 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:702341-706696:+ | gene-YGR116W_CBS436 | rna-NM_001181245.1_CBS436 | cds-NP_011631.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:692407-696762:+ | gene-YGR116W_CBS6412 | rna-NM_001181245.1_CBS6412 | cds-NP_011631.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:697341-701696:+ | gene-YGR116W_CBS6413 | rna-NM_001181245.1_CBS6413 | cds-NP_011631.1_CBS6413 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:720127-724482:+ | gene-YGR116W_CENPK1137D | rna-NM_001181245.1_CENPK1137D | cds-NP_011631.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:686831-691186:+ | gene-YGR116W_EthanolRed | rna-NM_001181245.1_EthanolRed | cds-NP_011631.1_EthanolRed | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:690640-694995:+ | gene-YGR116W_FaliES1 | rna-NM_001181245.1_FaliES1 | cds-NP_011631.1_FaliES1 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000092.1:2661-7015:- | gene-YGR116W_JAY291 | rna-NM_001181245.1_JAY291 | cds-NP_011631.1_JAY291 | 99.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:700140-704495:+ | gene-YGR116W_MUCL30387 | rna-NM_001181245.1_MUCL30387 | cds-NP_011631.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:701224-705579:+ | gene-YGR116W_MUCL30388 | rna-NM_001181245.1_MUCL30388 | cds-NP_011631.1_MUCL30388 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:696465-700820:+ | gene-YGR116W_MUCL39482 | rna-NM_001181245.1_MUCL39482 | cds-NP_011631.1_MUCL39482 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:706234-710589:+ | gene-YGR116W_MUCL42920 | rna-NM_001181245.1_MUCL42920 | cds-NP_011631.1_MUCL42920 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:720409-724764:+ | gene-YGR116W_NCIM3186 | rna-NM_001181245.1_NCIM3186 | cds-NP_011631.1_NCIM3186 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:691158-695513:+ | gene-YGR116W_NCYC1407 | rna-NM_001181245.1_NCYC1407 | cds-NP_011631.1_NCYC1407 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:704712-709067:+ | gene-YGR116W_PE2H3 | rna-NM_001181245.1_PE2H3 | cds-NP_011631.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:709830-714185:+ | gene-YGR116W_PE2H4 | rna-NM_001181245.1_PE2H4 | cds-NP_011631.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:720409-724764:+ | gene-YGR116W_S288C | rna-NM_001181245.1_S288C | cds-NP_011631.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:141725-146080:+ | gene-YGR116W_SA1 | rna-NM_001181245.1_SA1 | cds-NP_011631.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:711020-715375:+ | gene-YGR116W_ThermosaccDry | rna-NM_001181245.1_ThermosaccDry | cds-NP_011631.1_ThermosaccDry | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:813430-817785:+ | gene-YGR116W_VR1 | rna-NM_001181245.1_VR1 | cds-NP_011631.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:13414-17769:+ | gene-YGR116W_ZTW1 | rna-NM_001181245.1_ZTW1 | cds-NP_011631.1_ZTW1 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:700846-705201:+ | gene-YGR116W_Sparadoxus | rna-NM_001181245.1_Sparadoxus | cds-NP_011631.1_Sparadoxus | 92.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |