Gene name: SPT23
Reference locus (S288C): YKL020C
Gene biotype: protein_coding
Description: ER membrane protein involved in regulation of OLE1 transcription; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting; SPT23 has a paralog, MGA2, that arose from the whole genome duplication
Top 10 interactors (score): RSP5 (0.982); OLE1 (0.98); NPL4 (0.903); CDC48 (0.865); DGK1 (0.82); MGA2 (0.819); UBX2 (0.786); UFD1 (0.78); VPS64 (0.76); PPG1 (0.754); OPI3 (0.687); UFD2 (0.653); INO4 (0.626); UBP2 (0.609); OTU1 (0.607); INO2 (0.571); CHO2 (0.554); SSM4 (0.538); DOA1 (0.532); HMS1 (0.527)
Homologues (species, bitscore): ANK3 (Homo sapiens, 66.6); Ankrd28 (Mus musculus, 56.6); ank3a (Danio rerio, 61.6); ENSXETP00000051224 (Xenopus tropicalis, 66.2); Tnks (Drosophila melanogaster, 55.8); trp-4 (Caenorhabditis elegans, 62.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:384850-388098:- | gene-YKL020C_AKU4011 | rna-NM_001179586.1_AKU4011 | cds-NP_012905.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:255807-259055:+ | gene-YKL020C_BG1 | rna-NM_001179586.1_BG1 | cds-NP_012905.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:406552-409800:- | gene-YKL020C_Bruggeman | rna-NM_001179586.1_Bruggeman | cds-NP_012905.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:401660-404908:- | gene-YKL020C_CAT1 | rna-NM_001179586.1_CAT1 | cds-NP_012905.1_CAT1 | 99.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:397569-400817:- | gene-YKL020C_CBS1585 | rna-NM_001179586.1_CBS1585 | cds-NP_012905.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:396430-399678:- | gene-YKL020C_CBS436 | rna-NM_001179586.1_CBS436 | cds-NP_012905.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:381725-384973:- | gene-YKL020C_CBS6412 | rna-NM_001179586.1_CBS6412 | cds-NP_012905.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:397424-400672:- | gene-YKL020C_CBS6413 | rna-NM_001179586.1_CBS6413 | cds-NP_012905.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:398509-401757:- | gene-YKL020C_CENPK1137D | rna-NM_001179586.1_CENPK1137D | cds-NP_012905.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:395346-398594:- | gene-YKL020C_EthanolRed | rna-NM_001179586.1_EthanolRed | cds-NP_012905.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:397436-400684:- | gene-YKL020C_FaliES1 | rna-NM_001179586.1_FaliES1 | cds-NP_012905.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000142.1:30366-33614:+ | gene-YKL020C_JAY291 | rna-NM_001179586.1_JAY291 | cds-NP_012905.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:405867-409115:- | gene-YKL020C_MUCL30387 | rna-NM_001179586.1_MUCL30387 | cds-NP_012905.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:401476-404724:- | gene-YKL020C_MUCL30388 | rna-NM_001179586.1_MUCL30388 | cds-NP_012905.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:396886-400134:- | gene-YKL020C_MUCL39482 | rna-NM_001179586.1_MUCL39482 | cds-NP_012905.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:402713-405961:- | gene-YKL020C_MUCL42920 | rna-NM_001179586.1_MUCL42920 | cds-NP_012905.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:398821-402069:- | gene-YKL020C_NCIM3186 | rna-NM_001179586.1_NCIM3186 | cds-NP_012905.1_NCIM3186 | 98.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:397078-400326:- | gene-YKL020C_NCYC1407 | rna-NM_001179586.1_NCYC1407 | cds-NP_012905.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:421768-425016:- | gene-YKL020C_PE2H3 | rna-NM_001179586.1_PE2H3 | cds-NP_012905.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:406512-409760:- | gene-YKL020C_PE2H4 | rna-NM_001179586.1_PE2H4 | cds-NP_012905.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:398832-402080:- | gene-YKL020C_S288C | rna-NM_001179586.1_S288C | cds-NP_012905.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:77110-80358:- | gene-YKL020C_SA1 | rna-NM_001179586.1_SA1 | cds-NP_012905.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:397535-400783:- | gene-YKL020C_ThermosaccDry | rna-NM_001179586.1_ThermosaccDry | cds-NP_012905.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:396790-400038:- | gene-YKL020C_VR1 | rna-NM_001179586.1_VR1 | cds-NP_012905.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:395563-398811:- | gene-YKL020C_ZTW1 | rna-NM_001179586.1_ZTW1 | cds-NP_012905.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:420558-423818:- | gene-YKL020C_Sparadoxus | rna-NM_001179586.1_Sparadoxus | cds-NP_012905.1_Sparadoxus | 88.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |