Gene name: SPT16
Reference locus (S288C): YGL207W
Gene biotype: protein_coding
Description: Subunit of the heterodimeric FACT complex (Spt16p-Pob3p); FACT associates with chromatin via interaction with Nhp6Ap and Nhp6Bp, and reorganizes nucleosomes to facilitate access to DNA by RNA and DNA polymerases; specifically required for diauxic shift-induced H2B deposition onto rDNA genes; mutations cause reduced nucleosome occupancy over highly transcribed regions; coregulates transcription with Mot1p through preinitiation complex assembly and nucleosome organization
Top 10 interactors (score): HHT2 (0.999); SPT6 (0.999); CHD1 (0.999); HHF1 (0.999); SPT5 (0.999); SPT4 (0.999); PAF1 (0.999); CTR9 (0.999); HHT1 (0.999); POB3 (0.999); HTB1 (0.998); CKB2 (0.998); RTF1 (0.998); DST1 (0.998); LEO1 (0.998); HTA1 (0.998); CTF4 (0.997); HTA2 (0.997); HTB2 (0.996); CDC73 (0.996)
Homologues (species, bitscore): SUPT16H (Homo sapiens, 586.6); Supt16 (Mus musculus, 583.9); supt16h (Danio rerio, 599.0); supt16h (Xenopus tropicalis, 572.0); dre4 (Drosophila melanogaster, 558.1); F55A3.3 (Caenorhabditis elegans, 492.7); SPT16 (Arabidopsis thaliana, 528.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:100319-103426:+ | gene-YGL207W_AKU4011 | rna-NM_001181072.1_AKU4011 | cds-NP_011308.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:93380-96487:+ | gene-YGL207W_BG1 | rna-NM_001181072.1_BG1 | cds-NP_011308.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:101692-104799:+ | gene-YGL207W_Bruggeman | rna-NM_001181072.1_Bruggeman | cds-NP_011308.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:99492-102599:+ | gene-YGL207W_CAT1 | rna-NM_001181072.1_CAT1 | cds-NP_011308.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:104624-107731:+ | gene-YGL207W_CBS1585 | rna-NM_001181072.1_CBS1585 | cds-NP_011308.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:100188-103295:+ | gene-YGL207W_CBS436 | rna-NM_001181072.1_CBS436 | cds-NP_011308.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:91755-94862:+ | gene-YGL207W_CBS6412 | rna-NM_001181072.1_CBS6412 | cds-NP_011308.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:98459-101566:+ | gene-YGL207W_CBS6413 | rna-NM_001181072.1_CBS6413 | cds-NP_011308.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:99002-102109:+ | gene-YGL207W_CENPK1137D | rna-NM_001181072.1_CENPK1137D | cds-NP_011308.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:91124-94231:+ | gene-YGL207W_EthanolRed | rna-NM_001181072.1_EthanolRed | cds-NP_011308.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:91967-95074:+ | gene-YGL207W_FaliES1 | rna-NM_001181072.1_FaliES1 | cds-NP_011308.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000397.1:18371-21478:+ | gene-YGL207W_JAY291 | rna-NM_001181072.1_JAY291 | cds-NP_011308.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:100739-103846:+ | gene-YGL207W_MUCL30387 | rna-NM_001181072.1_MUCL30387 | cds-NP_011308.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:102921-106028:+ | gene-YGL207W_MUCL30388 | rna-NM_001181072.1_MUCL30388 | cds-NP_011308.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:101137-104244:+ | gene-YGL207W_MUCL39482 | rna-NM_001181072.1_MUCL39482 | cds-NP_011308.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:104242-107349:+ | gene-YGL207W_MUCL42920 | rna-NM_001181072.1_MUCL42920 | cds-NP_011308.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:98969-102076:+ | gene-YGL207W_NCIM3186 | rna-NM_001181072.1_NCIM3186 | cds-NP_011308.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:92859-95966:+ | gene-YGL207W_NCYC1407 | rna-NM_001181072.1_NCYC1407 | cds-NP_011308.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:95685-98792:+ | gene-YGL207W_PE2H3 | rna-NM_001181072.1_PE2H3 | cds-NP_011308.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:95233-98340:+ | gene-YGL207W_PE2H4 | rna-NM_001181072.1_PE2H4 | cds-NP_011308.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:98969-102076:+ | gene-YGL207W_S288C | rna-NM_001181072.1_S288C | cds-NP_011308.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:273203-276310:- | gene-YGL207W_SA1 | rna-NM_001181072.1_SA1 | cds-NP_011308.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:92228-95335:+ | gene-YGL207W_ThermosaccDry | rna-NM_001181072.1_ThermosaccDry | cds-NP_011308.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:100100-103207:+ | gene-YGL207W_VR1 | rna-NM_001181072.1_VR1 | cds-NP_011308.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:91264-94371:+ | gene-YGL207W_ZTW1 | rna-NM_001181072.1_ZTW1 | cds-NP_011308.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:98475-101582:+ | gene-YGL207W_Sparadoxus | rna-NM_001181072.1_Sparadoxus | cds-NP_011308.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |