Gene name: SPS1
Reference locus (S288C): YDR523C
Gene biotype: protein_coding
Description: Sporulation-specific protein 1; Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis
Top 10 interactors (score): HYM1 (0.957); FAR8 (0.935); FAR11 (0.882); TPD3 (0.846); PPH21 (0.841); FAR10 (0.838); VPS64 (0.838); SOG2 (0.814); SPS2 (0.809); PPH22 (0.793); SHC1 (0.751); BMH2 (0.747); BMH1 (0.747); RIM1 (0.746); MOB1 (0.69); PKP1 (0.676); CCT8 (0.631); CCT7 (0.625); TAO3 (0.624); TEM1 (0.62)
Homologues (species, bitscore): STK25 (Homo sapiens, 268.9); Stk25 (Mus musculus, 268.5); mst4 (Danio rerio, 271.9); stk24 (Xenopus tropicalis, 271.9); GckIII (Drosophila melanogaster, 274.2); gck-1 (Caenorhabditis elegans, 262.7); AT3G15220 (Arabidopsis thaliana, 266.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1425607-1427079:- | gene-YDR523C_AKU4011 | rna-NM_001180831.1_AKU4011 | cds-NP_010811.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:67231-68703:- | gene-YDR523C_BG1 | rna-NM_001180831.1_BG1 | cds-NP_010811.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1456900-1458372:- | gene-YDR523C_Bruggeman | rna-NM_001180831.1_Bruggeman | cds-NP_010811.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1434065-1435537:- | gene-YDR523C_CAT1 | rna-NM_001180831.1_CAT1 | cds-NP_010811.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1420335-1421807:- | gene-YDR523C_CBS1585 | rna-NM_001180831.1_CBS1585 | cds-NP_010811.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1439541-1441013:- | gene-YDR523C_CBS436 | rna-NM_001180831.1_CBS436 | cds-NP_010811.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1415498-1416970:- | gene-YDR523C_CBS6412 | rna-NM_001180831.1_CBS6412 | cds-NP_010811.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1438995-1440467:- | gene-YDR523C_CBS6413 | rna-NM_001180831.1_CBS6413 | cds-NP_010811.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1484253-1485725:- | gene-YDR523C_CENPK1137D | rna-NM_001180831.1_CENPK1137D | cds-NP_010811.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1428867-1430339:- | gene-YDR523C_EthanolRed | rna-NM_001180831.1_EthanolRed | cds-NP_010811.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1432419-1433891:- | gene-YDR523C_FaliES1 | rna-NM_001180831.1_FaliES1 | cds-NP_010811.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:130767-132239:- | gene-YDR523C_JAY291 | rna-NM_001180831.1_JAY291 | cds-NP_010811.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1439994-1441466:- | gene-YDR523C_MUCL30387 | rna-NM_001180831.1_MUCL30387 | cds-NP_010811.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1421439-1422911:- | gene-YDR523C_MUCL30388 | rna-NM_001180831.1_MUCL30388 | cds-NP_010811.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1411833-1413305:- | gene-YDR523C_MUCL39482 | rna-NM_001180831.1_MUCL39482 | cds-NP_010811.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1354469-1355941:- | gene-YDR523C_MUCL42920 | rna-NM_001180831.1_MUCL42920 | cds-NP_010811.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1485489-1486961:- | gene-YDR523C_NCIM3186 | rna-NM_001180831.1_NCIM3186 | cds-NP_010811.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1425125-1426597:- | gene-YDR523C_NCYC1407 | rna-NM_001180831.1_NCYC1407 | cds-NP_010811.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1436035-1437507:- | gene-YDR523C_PE2H3 | rna-NM_001180831.1_PE2H3 | cds-NP_010811.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1441503-1442975:- | gene-YDR523C_PE2H4 | rna-NM_001180831.1_PE2H4 | cds-NP_010811.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1485566-1487038:- | gene-YDR523C_S288C | rna-NM_001180831.1_S288C | cds-NP_010811.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:130075-131547:+ | gene-YDR523C_SA1 | rna-NM_001180831.1_SA1 | cds-NP_010811.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1436641-1438113:- | gene-YDR523C_ThermosaccDry | rna-NM_001180831.1_ThermosaccDry | cds-NP_010811.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1452412-1453884:- | gene-YDR523C_VR1 | rna-NM_001180831.1_VR1 | cds-NP_010811.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:479285-480757:- | gene-YDR523C_ZTW1 | rna-NM_001180831.1_ZTW1 | cds-NP_010811.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1445559-1447031:- | gene-YDR523C_Sparadoxus | rna-NM_001180831.1_Sparadoxus | cds-NP_010811.1_Sparadoxus | 91.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |