Gene name: SPP1
Reference locus (S288C): YPL138C
Gene biotype: protein_coding
Description: COMPASS component SPP1; Subunit of COMPASS (Set1C); a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; promotes meiotic DSB formation by interacting with H3K4me3 and Rec107p, a protein required for Spo11p-catalyzed DSB formation located on chromosome axes; interacts with Orc2p; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein; relocalizes to cytosol in response to hypoxia
Top 10 interactors (score): BRE2 (0.999); SDC1 (0.999); SWD2 (0.999); SWD3 (0.999); SET1 (0.999); SWD1 (0.999); SHG1 (0.989); HHT1 (0.984); HHT2 (0.974); SET2 (0.95); REC107 (0.932); ISW2 (0.902); IRC5 (0.902); ISW1 (0.902); HAT2 (0.895); MSI1 (0.895); SWR1 (0.843); RPS31 (0.841); UBI4 (0.841); RPL40A (0.84)
Homologues (species, bitscore): CXXC1 (Homo sapiens, 59.3); Cxxc1 (Mus musculus, 59.3); cxxc1l (Danio rerio, 59.3); cxxc1 (Xenopus tropicalis, 58.9); CG17440 (Drosophila melanogaster, 55.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:269019-270080:- | gene-YPL138C_AKU4011 | rna-NM_001183952.1_AKU4011 | cds-NP_015187.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:474706-475767:- | gene-YPL138C_BG1 | rna-NM_001183952.1_BG1 | cds-NP_015187.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:295015-296076:- | gene-YPL138C_Bruggeman | rna-NM_001183952.1_Bruggeman | cds-NP_015187.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:291693-292754:- | gene-YPL138C_CAT1 | rna-NM_001183952.1_CAT1 | cds-NP_015187.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:273086-274147:- | gene-YPL138C_CBS1585 | rna-NM_001183952.1_CBS1585 | cds-NP_015187.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:287757-288818:- | gene-YPL138C_CBS436 | rna-NM_001183952.1_CBS436 | cds-NP_015187.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:277761-278822:- | gene-YPL138C_CBS6412 | rna-NM_001183952.1_CBS6412 | cds-NP_015187.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:269725-270786:- | gene-YPL138C_CBS6413 | rna-NM_001183952.1_CBS6413 | cds-NP_015187.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:291268-292329:- | gene-YPL138C_CENPK1137D | rna-NM_001183952.1_CENPK1137D | cds-NP_015187.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:267706-268767:- | gene-YPL138C_EthanolRed | rna-NM_001183952.1_EthanolRed | cds-NP_015187.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:275298-276359:- | gene-YPL138C_FaliES1 | rna-NM_001183952.1_FaliES1 | cds-NP_015187.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:89486-90547:+ | gene-YPL138C_JAY291 | rna-NM_001183952.1_JAY291 | cds-NP_015187.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:286259-287320:- | gene-YPL138C_MUCL30387 | rna-NM_001183952.1_MUCL30387 | cds-NP_015187.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:284272-285333:- | gene-YPL138C_MUCL30388 | rna-NM_001183952.1_MUCL30388 | cds-NP_015187.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:266415-267476:- | gene-YPL138C_MUCL39482 | rna-NM_001183952.1_MUCL39482 | cds-NP_015187.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:323656-324717:- | gene-YPL138C_MUCL42920 | rna-NM_001183952.1_MUCL42920 | cds-NP_015187.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:291349-292410:- | gene-YPL138C_NCIM3186 | rna-NM_001183952.1_NCIM3186 | cds-NP_015187.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:272875-273936:- | gene-YPL138C_NCYC1407 | rna-NM_001183952.1_NCYC1407 | cds-NP_015187.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:280321-281382:- | gene-YPL138C_PE2H3 | rna-NM_001183952.1_PE2H3 | cds-NP_015187.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:279956-281017:- | gene-YPL138C_PE2H4 | rna-NM_001183952.1_PE2H4 | cds-NP_015187.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:291366-292427:- | gene-YPL138C_S288C | rna-NM_001183952.1_S288C | cds-NP_015187.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:81256-82317:+ | gene-YPL138C_SA1 | rna-NM_001183952.1_SA1 | cds-NP_015187.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:275096-276157:- | gene-YPL138C_ThermosaccDry | rna-NM_001183952.1_ThermosaccDry | cds-NP_015187.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:290077-291138:- | gene-YPL138C_VR1 | rna-NM_001183952.1_VR1 | cds-NP_015187.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:274426-275487:- | gene-YPL138C_ZTW1 | rna-NM_001183952.1_ZTW1 | cds-NP_015187.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:276133-277194:- | gene-YPL138C_Sparadoxus | rna-NM_001183952.1_Sparadoxus | cds-NP_015187.1_Sparadoxus | 89.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |