Gene name: SPO14
Reference locus (S288C): YKR031C
Gene biotype: protein_coding
Description: Phospholipase D; catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis; participates in transcription initiation and/or early elongation of specific genes; interacts with "foot domain" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions
Top 10 interactors (score): PAH1 (0.989); SEC14 (0.984); PSD1 (0.982); ARF1 (0.976); ALE1 (0.974); OPI3 (0.972); DGK1 (0.97); CPT1 (0.966); CDS1 (0.965); LPP1 (0.964); PSD2 (0.96); RHO1 (0.958); DPP1 (0.955); CDC42 (0.952); CHO2 (0.952); ARF2 (0.946); TGL4 (0.945); SPO20 (0.943); CHO1 (0.942); EPT1 (0.939)
Homologues (species, bitscore): PLD2 (Homo sapiens, 417.5); Pld1 (Mus musculus, 415.2); pld2 (Danio rerio, 420.6); pld1 (Xenopus tropicalis, 418.3); Pld (Drosophila melanogaster, 362.1); pld-1 (Caenorhabditis elegans, 333.6); PLDP1 (Arabidopsis thaliana, 406.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:487006-492057:- | gene-YKR031C_AKU4011 | rna-NM_001179821.3_AKU4011 | cds-NP_012956.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:151416-156467:+ | gene-YKR031C_BG1 | rna-NM_001179821.3_BG1 | cds-NP_012956.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:508936-514236:- | gene-YKR031C_Bruggeman | rna-NM_001179821.3_Bruggeman | cds-NP_012956.3_Bruggeman | 94.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:504433-509484:- | gene-YKR031C_CAT1 | rna-NM_001179821.3_CAT1 | cds-NP_012956.3_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:499746-504797:- | gene-YKR031C_CBS1585 | rna-NM_001179821.3_CBS1585 | cds-NP_012956.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:498587-503638:- | gene-YKR031C_CBS436 | rna-NM_001179821.3_CBS436 | cds-NP_012956.3_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:483907-488958:- | gene-YKR031C_CBS6412 | rna-NM_001179821.3_CBS6412 | cds-NP_012956.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:499575-504626:- | gene-YKR031C_CBS6413 | rna-NM_001179821.3_CBS6413 | cds-NP_012956.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:501086-506137:- | gene-YKR031C_CENPK1137D | rna-NM_001179821.3_CENPK1137D | cds-NP_012956.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:497272-502323:- | gene-YKR031C_EthanolRed | rna-NM_001179821.3_EthanolRed | cds-NP_012956.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:500405-505456:- | gene-YKR031C_FaliES1 | rna-NM_001179821.3_FaliES1 | cds-NP_012956.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000077.1:48289-53340:+ | gene-YKR031C_JAY291 | rna-NM_001179821.3_JAY291 | cds-NP_012956.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:509341-514392:- | gene-YKR031C_MUCL30387 | rna-NM_001179821.3_MUCL30387 | cds-NP_012956.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:503696-508996:- | gene-YKR031C_MUCL30388 | rna-NM_001179821.3_MUCL30388 | cds-NP_012956.3_MUCL30388 | 94.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:499064-504115:- | gene-YKR031C_MUCL39482 | rna-NM_001179821.3_MUCL39482 | cds-NP_012956.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:505099-510150:- | gene-YKR031C_MUCL42920 | rna-NM_001179821.3_MUCL42920 | cds-NP_012956.3_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:501333-506384:- | gene-YKR031C_NCIM3186 | rna-NM_001179821.3_NCIM3186 | cds-NP_012956.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:499270-504321:- | gene-YKR031C_NCYC1407 | rna-NM_001179821.3_NCYC1407 | cds-NP_012956.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:524271-529322:- | gene-YKR031C_PE2H3 | rna-NM_001179821.3_PE2H3 | cds-NP_012956.3_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:508994-514045:- | gene-YKR031C_PE2H4 | rna-NM_001179821.3_PE2H4 | cds-NP_012956.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:501344-506395:- | gene-YKR031C_S288C | rna-NM_001179821.3_S288C | cds-NP_012956.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000078.1:7354-12405:+ | gene-YKR031C_SA1 | rna-NM_001179821.3_SA1 | cds-NP_012956.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:499658-504709:- | gene-YKR031C_ThermosaccDry | rna-NM_001179821.3_ThermosaccDry | cds-NP_012956.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:499291-504342:- | gene-YKR031C_VR1 | rna-NM_001179821.3_VR1 | cds-NP_012956.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:497705-502756:- | gene-YKR031C_ZTW1 | rna-NM_001179821.3_ZTW1 | cds-NP_012956.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:522998-528049:- | gene-YKR031C_Sparadoxus | rna-NM_001179821.3_Sparadoxus | cds-NP_012956.3_Sparadoxus | 90.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |