Gene name: SPN1
Reference locus (S288C): YPR133C
Gene biotype: protein_coding
Description: Transcription factor SPN1; Protein involved in RNA polymerase II transcription; is constitutively recruited to the CYC1 promoter and is required for recruitment of chromatin remodeling factors for the expression of CYC1 gene; interacts genetically or physically with RNAP II, TBP, TFIIS, and chromatin remodelling factors; central domain highly conserved throughout eukaryotes; mutations confer an Spt- phenotype
Top 10 interactors (score): DST1 (0.999); SPT6 (0.999); SPT5 (0.999); SPT4 (0.996); LEO1 (0.995); POB3 (0.991); SET2 (0.989); CHD1 (0.988); RPO21 (0.964); RTF1 (0.935); CTR9 (0.929); RPB2 (0.925); SPT16 (0.923); PCF11 (0.918); YRA1 (0.897); FCP1 (0.895); HHT1 (0.893); ELA1 (0.866); RPB5 (0.862); ELF1 (0.847)
Homologues (species, bitscore): IWS1 (Homo sapiens, 105.9); Iws1 (Mus musculus, 105.9); IWS1 (Danio rerio, 100.9); iws1 (Xenopus tropicalis, 104.0); CG9915 (Drosophila melanogaster, 88.6); F13B12.1 (Caenorhabditis elegans, 87.8); IWS1 (Arabidopsis thaliana, 99.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:767664-768896:- | gene-YPR133C_AKU4011 | rna-NM_001184230.1_AKU4011 | cds-NP_015458.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:128470-129702:+ | gene-YPR133C_BG1 | rna-NM_001184230.1_BG1 | cds-NP_015458.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:848314-849546:- | gene-YPR133C_Bruggeman | rna-NM_001184230.1_Bruggeman | cds-NP_015458.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:890238-891470:- | gene-YPR133C_CAT1 | rna-NM_001184230.1_CAT1 | cds-NP_015458.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:771920-773152:- | gene-YPR133C_CBS1585 | rna-NM_001184230.1_CBS1585 | cds-NP_015458.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:786394-787626:- | gene-YPR133C_CBS436 | rna-NM_001184230.1_CBS436 | cds-NP_015458.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:774644-775876:- | gene-YPR133C_CBS6412 | rna-NM_001184230.1_CBS6412 | cds-NP_015458.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:769366-770598:- | gene-YPR133C_CBS6413 | rna-NM_001184230.1_CBS6413 | cds-NP_015458.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:796033-797265:- | gene-YPR133C_CENPK1137D | rna-NM_001184230.1_CENPK1137D | cds-NP_015458.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1089830-1091062:- | gene-YPR133C_EthanolRed | rna-NM_001184230.1_EthanolRed | cds-NP_015458.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:769377-770609:- | gene-YPR133C_FaliES1 | rna-NM_001184230.1_FaliES1 | cds-NP_015458.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000036.1:26654-27886:- | gene-YPR133C_JAY291 | rna-NM_001184230.1_JAY291 | cds-NP_015458.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:788505-789737:- | gene-YPR133C_MUCL30387 | rna-NM_001184230.1_MUCL30387 | cds-NP_015458.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:788470-789702:- | gene-YPR133C_MUCL30388 | rna-NM_001184230.1_MUCL30388 | cds-NP_015458.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:764428-765660:- | gene-YPR133C_MUCL39482 | rna-NM_001184230.1_MUCL39482 | cds-NP_015458.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:828225-829457:- | gene-YPR133C_MUCL42920 | rna-NM_001184230.1_MUCL42920 | cds-NP_015458.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:795961-797193:- | gene-YPR133C_NCIM3186 | rna-NM_001184230.1_NCIM3186 | cds-NP_015458.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:773021-774253:- | gene-YPR133C_NCYC1407 | rna-NM_001184230.1_NCYC1407 | cds-NP_015458.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:779742-780974:- | gene-YPR133C_PE2H3 | rna-NM_001184230.1_PE2H3 | cds-NP_015458.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:779390-780622:- | gene-YPR133C_PE2H4 | rna-NM_001184230.1_PE2H4 | cds-NP_015458.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:795978-797210:- | gene-YPR133C_S288C | rna-NM_001184230.1_S288C | cds-NP_015458.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000028.1:93774-95006:- | gene-YPR133C_SA1 | rna-NM_001184230.1_SA1 | cds-NP_015458.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:768822-770054:- | gene-YPR133C_ThermosaccDry | rna-NM_001184230.1_ThermosaccDry | cds-NP_015458.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:790647-791879:- | gene-YPR133C_VR1 | rna-NM_001184230.1_VR1 | cds-NP_015458.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:772577-773809:- | gene-YPR133C_ZTW1 | rna-NM_001184230.1_ZTW1 | cds-NP_015458.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:774540-775772:- | gene-YPR133C_Sparadoxus | rna-NM_001184230.1_Sparadoxus | cds-NP_015458.1_Sparadoxus | 88.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |