Gene name: SPL2
Reference locus (S288C): YHR136C
Gene biotype: protein_coding
Description: Protein with similarity to cyclin-dependent kinase inhibitors; downregulates low-affinity phosphate transport during phosphate limitation by targeting Pho87p to the vacuole; upstream region harbors putative hypoxia response element (HRE) cluster; overproduction suppresses a plc1 null mutation; promoter shows an increase in Snf2p occupancy after heat shock; GFP-fusion protein localizes to the cytoplasm
Top 10 interactors (score): PHO84 (0.996); VTC3 (0.973); PHO11 (0.959); PHM6 (0.955); VTC1 (0.947); PHO12 (0.943); VTC4 (0.92); PHO87 (0.914); PHO90 (0.9); PHO89 (0.898); PHO4 (0.827); PHO81 (0.805); PHO5 (0.782); PHO91 (0.76); PHO80 (0.696); VTC2 (0.621); YGL214W (0.616); BSC1 (0.616); YDL196W (0.575); NFS1 (0.573)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:361586-362032:- | gene-YHR136C_AKU4011 | rna-NM_001179266.1_AKU4011 | cds-NP_012004.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:155822-156268:+ | gene-YHR136C_BG1 | rna-NM_001179266.1_BG1 | cds-NP_012004.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:368803-369249:- | gene-YHR136C_Bruggeman | rna-NM_001179266.1_Bruggeman | cds-NP_012004.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:364002-364448:- | gene-YHR136C_CAT1 | rna-NM_001179266.1_CAT1 | cds-NP_012004.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:360608-361054:- | gene-YHR136C_CBS1585 | rna-NM_001179266.1_CBS1585 | cds-NP_012004.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:357961-358407:- | gene-YHR136C_CBS436 | rna-NM_001179266.1_CBS436 | cds-NP_012004.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:362049-362495:- | gene-YHR136C_CBS6412 | rna-NM_001179266.1_CBS6412 | cds-NP_012004.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:361638-362084:- | gene-YHR136C_CBS6413 | rna-NM_001179266.1_CBS6413 | cds-NP_012004.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:367827-368273:- | gene-YHR136C_CENPK1137D | rna-NM_001179266.1_CENPK1137D | cds-NP_012004.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:420496-420942:- | gene-YHR136C_EthanolRed | rna-NM_001179266.1_EthanolRed | cds-NP_012004.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:361984-362430:- | gene-YHR136C_FaliES1 | rna-NM_001179266.1_FaliES1 | cds-NP_012004.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000275.1:4114-4560:- | gene-YHR136C_JAY291 | rna-NM_001179266.1_JAY291 | cds-NP_012004.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:368533-368979:- | gene-YHR136C_MUCL30387 | rna-NM_001179266.1_MUCL30387 | cds-NP_012004.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:368798-369244:- | gene-YHR136C_MUCL30388 | rna-NM_001179266.1_MUCL30388 | cds-NP_012004.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:360952-361398:- | gene-YHR136C_MUCL39482 | rna-NM_001179266.1_MUCL39482 | cds-NP_012004.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:367165-367611:- | gene-YHR136C_MUCL42920 | rna-NM_001179266.1_MUCL42920 | cds-NP_012004.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:374536-374982:- | gene-YHR136C_NCIM3186 | rna-NM_001179266.1_NCIM3186 | cds-NP_012004.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:363160-363606:- | gene-YHR136C_NCYC1407 | rna-NM_001179266.1_NCYC1407 | cds-NP_012004.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:362601-363047:- | gene-YHR136C_PE2H3 | rna-NM_001179266.1_PE2H3 | cds-NP_012004.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:370028-370474:- | gene-YHR136C_PE2H4 | rna-NM_001179266.1_PE2H4 | cds-NP_012004.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:374654-375100:- | gene-YHR136C_S288C | rna-NM_001179266.1_S288C | cds-NP_012004.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000103.1:14296-14742:+ | gene-YHR136C_SA1 | rna-NM_001179266.1_SA1 | cds-NP_012004.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:363067-363513:- | gene-YHR136C_ThermosaccDry | rna-NM_001179266.1_ThermosaccDry | cds-NP_012004.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:371511-371957:- | gene-YHR136C_VR1 | rna-NM_001179266.1_VR1 | cds-NP_012004.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:354065-354511:- | gene-YHR136C_ZTW1 | rna-NM_001179266.1_ZTW1 | cds-NP_012004.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |