Gene name: SPF1
Reference locus (S288C): YEL031W
Gene biotype: protein_coding
Description: Manganese-transporting ATPase 1; P-type ATPase, ion transporter of the ER membrane; required to maintain normal lipid composition of intracellular compartments and proper targeting of mitochondrial outer membrane tail-anchored proteins; involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1
Top 10 interactors (score): LRG1 (0.908); CHC1 (0.892); YVC1 (0.852); CRM1 (0.839); CCH1 (0.809); TIF4632 (0.793); TIF4631 (0.793); RTG3 (0.79); YPK2 (0.788); PMR1 (0.786); RTG1 (0.784); VCX1 (0.726); UFD4 (0.722); GDT1 (0.704); KAR2 (0.684); GET1 (0.678); KRE5 (0.677); YTA7 (0.676); GAS1 (0.673); LAS21 (0.664)
Homologues (species, bitscore): ATP13A1 (Homo sapiens, 849.0); Atp13a1 (Mus musculus, 841.6); atp13a (Danio rerio, 894.0); atp13a1 (Xenopus tropicalis, 877.1); CG6230 (Drosophila melanogaster, 840.1); catp-8 (Caenorhabditis elegans, 842.0); PDR2 (Arabidopsis thaliana, 846.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:84313-87960:+ | gene-YEL031W_AKU4011 | rna-NM_001178846.3_AKU4011 | cds-NP_010883.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:338089-341736:- | gene-YEL031W_BG1 | rna-NM_001178846.3_BG1 | cds-NP_010883.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:88688-92335:+ | gene-YEL031W_Bruggeman | rna-NM_001178846.3_Bruggeman | cds-NP_010883.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:86220-89867:+ | gene-YEL031W_CAT1 | rna-NM_001178846.3_CAT1 | cds-NP_010883.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:84255-87902:+ | gene-YEL031W_CBS1585 | rna-NM_001178846.3_CBS1585 | cds-NP_010883.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:85866-89513:+ | gene-YEL031W_CBS436 | rna-NM_001178846.3_CBS436 | cds-NP_010883.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:84507-88154:+ | gene-YEL031W_CBS6412 | rna-NM_001178846.3_CBS6412 | cds-NP_010883.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:89147-92794:+ | gene-YEL031W_CBS6413 | rna-NM_001178846.3_CBS6413 | cds-NP_010883.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:88117-91764:+ | gene-YEL031W_CENPK1137D | rna-NM_001178846.3_CENPK1137D | cds-NP_010883.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:84062-87709:+ | gene-YEL031W_EthanolRed | rna-NM_001178846.3_EthanolRed | cds-NP_010883.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:84328-87975:+ | gene-YEL031W_FaliES1 | rna-NM_001178846.3_FaliES1 | cds-NP_010883.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000398.1:3770-7417:+ | gene-YEL031W_JAY291 | rna-NM_001178846.3_JAY291 | cds-NP_010883.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:88542-92189:+ | gene-YEL031W_MUCL30387 | rna-NM_001178846.3_MUCL30387 | cds-NP_010883.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:84298-87945:+ | gene-YEL031W_MUCL30388 | rna-NM_001178846.3_MUCL30388 | cds-NP_010883.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:83624-87271:+ | gene-YEL031W_MUCL39482 | rna-NM_001178846.3_MUCL39482 | cds-NP_010883.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:88258-91905:+ | gene-YEL031W_MUCL42920 | rna-NM_001178846.3_MUCL42920 | cds-NP_010883.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:90257-93904:+ | gene-YEL031W_NCIM3186 | rna-NM_001178846.3_NCIM3186 | cds-NP_010883.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:88718-92365:+ | gene-YEL031W_NCYC1407 | rna-NM_001178846.3_NCYC1407 | cds-NP_010883.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:92735-96382:+ | gene-YEL031W_PE2H3 | rna-NM_001178846.3_PE2H3 | cds-NP_010883.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:88650-92297:+ | gene-YEL031W_PE2H4 | rna-NM_001178846.3_PE2H4 | cds-NP_010883.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:90258-93905:+ | gene-YEL031W_S288C | rna-NM_001178846.3_S288C | cds-NP_010883.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000020.1:149383-153030:- | gene-YEL031W_SA1 | rna-NM_001178846.3_SA1 | cds-NP_010883.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:84726-88373:+ | gene-YEL031W_ThermosaccDry | rna-NM_001178846.3_ThermosaccDry | cds-NP_010883.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:83929-87576:+ | gene-YEL031W_VR1 | rna-NM_001178846.3_VR1 | cds-NP_010883.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:83667-87314:+ | gene-YEL031W_ZTW1 | rna-NM_001178846.3_ZTW1 | cds-NP_010883.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:86329-89976:+ | gene-YEL031W_Sparadoxus | rna-NM_001178846.3_Sparadoxus | cds-NP_010883.3_Sparadoxus | 93.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |