Gene name: SPE4
Reference locus (S288C): YLR146C
Gene biotype: protein_coding
Description: Spermine synthase; required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid
Top 10 interactors (score): SPE2 (0.996); SPE3 (0.987); SPE1 (0.969); MEU1 (0.962); FMS1 (0.937); CAR1 (0.771); ARG5,6 (0.73); YJL052C-A (0.717); ARG1 (0.713); YOR268C (0.712); DYS1 (0.688); GCD14 (0.672); CAR2 (0.65); CDC34 (0.649); ARG4 (0.647); RPL26B (0.645); RPL26A (0.645); NIT3 (0.641); YBL055C (0.634); LIA1 (0.609)
Homologues (species, bitscore): SRM (Homo sapiens, 293.9); Srm (Mus musculus, 294.7); srm (Danio rerio, 292.7); srm (Xenopus tropicalis, 287.7); SpdS (Drosophila melanogaster, 271.9); spds-1 (Caenorhabditis elegans, 263.5); SPDS1 (Arabidopsis thaliana, 261.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:415305-416207:- | gene-YLR146C_AKU4011 | rna-NM_001182033.1_AKU4011 | cds-NP_013247.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:379074-379976:- | gene-YLR146C_BG1 | rna-NM_001182033.1_BG1 | cds-NP_013247.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:427201-428103:- | gene-YLR146C_Bruggeman | rna-NM_001182033.1_Bruggeman | cds-NP_013247.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:426584-427486:- | gene-YLR146C_CAT1 | rna-NM_001182033.1_CAT1 | cds-NP_013247.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:422448-423350:- | gene-YLR146C_CBS1585 | rna-NM_001182033.1_CBS1585 | cds-NP_013247.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:412683-413585:- | gene-YLR146C_CBS436 | rna-NM_001182033.1_CBS436 | cds-NP_013247.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:420866-421768:- | gene-YLR146C_CBS6412 | rna-NM_001182033.1_CBS6412 | cds-NP_013247.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:422713-423615:- | gene-YLR146C_CBS6413 | rna-NM_001182033.1_CBS6413 | cds-NP_013247.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:417841-418743:- | gene-YLR146C_CENPK1137D | rna-NM_001182033.1_CENPK1137D | cds-NP_013247.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:415506-416408:- | gene-YLR146C_EthanolRed | rna-NM_001182033.1_EthanolRed | cds-NP_013247.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:415017-415919:- | gene-YLR146C_FaliES1 | rna-NM_001182033.1_FaliES1 | cds-NP_013247.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000061.1:21675-22577:- | gene-YLR146C_JAY291 | rna-NM_001182033.1_JAY291 | cds-NP_013247.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:427206-428108:- | gene-YLR146C_MUCL30387 | rna-NM_001182033.1_MUCL30387 | cds-NP_013247.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:432006-432908:- | gene-YLR146C_MUCL30388 | rna-NM_001182033.1_MUCL30388 | cds-NP_013247.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:422957-423859:- | gene-YLR146C_MUCL39482 | rna-NM_001182033.1_MUCL39482 | cds-NP_013247.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:423111-424013:- | gene-YLR146C_MUCL42920 | rna-NM_001182033.1_MUCL42920 | cds-NP_013247.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:432797-433699:- | gene-YLR146C_NCIM3186 | rna-NM_001182033.1_NCIM3186 | cds-NP_013247.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:415229-416131:- | gene-YLR146C_NCYC1407 | rna-NM_001182033.1_NCYC1407 | cds-NP_013247.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:420784-421686:- | gene-YLR146C_PE2H3 | rna-NM_001182033.1_PE2H3 | cds-NP_013247.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:420525-421427:- | gene-YLR146C_PE2H4 | rna-NM_001182033.1_PE2H4 | cds-NP_013247.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:432823-433725:- | gene-YLR146C_S288C | rna-NM_001182033.1_S288C | cds-NP_013247.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000055.1:58720-59622:- | gene-YLR146C_SA1 | rna-NM_001182033.1_SA1 | cds-NP_013247.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:416227-417129:- | gene-YLR146C_ThermosaccDry | rna-NM_001182033.1_ThermosaccDry | cds-NP_013247.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:428925-429827:- | gene-YLR146C_VR1 | rna-NM_001182033.1_VR1 | cds-NP_013247.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:414013-414915:- | gene-YLR146C_ZTW1 | rna-NM_001182033.1_ZTW1 | cds-NP_013247.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:424160-425062:- | gene-YLR146C_Sparadoxus | rna-NM_001182033.1_Sparadoxus | cds-NP_013247.1_Sparadoxus | 89.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |