SPE3 (YPR069C)


Gene profile

Gene name: SPE3
Reference locus (S288C): YPR069C
Gene biotype: protein_coding

Description: Spermidine synthase; involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid; spermidine is required for growth of wild-type cells

Top 10 interactors (score): SPE1 (0.999); SPE2 (0.998); MEU1 (0.987); SPE4 (0.987); FMS1 (0.98); CAR1 (0.937); LYS9 (0.875); ARG1 (0.786); HYP2 (0.772); ANB1 (0.736); CAR2 (0.734); DYS1 (0.731); ERP5 (0.727); ARG5,6 (0.712); NIT3 (0.695); RRP6 (0.693); ARG4 (0.679); LIA1 (0.679); GCV1 (0.667); RPS20 (0.654)

Homologues (species, bitscore): SRM (Homo sapiens, 376.3); Srm (Mus musculus, 367.9); srm (Danio rerio, 370.9); srm (Xenopus tropicalis, 377.5); SpdS (Drosophila melanogaster, 298.1); spds-1 (Caenorhabditis elegans, 314.7); SPDS1 (Arabidopsis thaliana, 312.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:656234-657115:- gene-YPR069C_AKU4011 rna-NM_001184166.1_AKU4011 cds-NP_015394.1_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:240576-241457:+ gene-YPR069C_BG1 rna-NM_001184166.1_BG1 cds-NP_015394.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:733901-734782:- gene-YPR069C_Bruggeman rna-NM_001184166.1_Bruggeman cds-NP_015394.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:777345-778226:- gene-YPR069C_CAT1 rna-NM_001184166.1_CAT1 cds-NP_015394.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:659922-660803:- gene-YPR069C_CBS1585 rna-NM_001184166.1_CBS1585 cds-NP_015394.1_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:674287-675168:- gene-YPR069C_CBS436 rna-NM_001184166.1_CBS436 cds-NP_015394.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:663669-664550:- gene-YPR069C_CBS6412 rna-NM_001184166.1_CBS6412 cds-NP_015394.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:656868-657749:- gene-YPR069C_CBS6413 rna-NM_001184166.1_CBS6413 cds-NP_015394.1_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:684519-685400:- gene-YPR069C_CENPK1137D rna-NM_001184166.1_CENPK1137D cds-NP_015394.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:983428-984309:- gene-YPR069C_EthanolRed rna-NM_001184166.1_EthanolRed cds-NP_015394.1_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:662065-662946:- gene-YPR069C_FaliES1 rna-NM_001184166.1_FaliES1 cds-NP_015394.1_FaliES1 99.5 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000446.1:34007-34888:- gene-YPR069C_JAY291 rna-NM_001184166.1_JAY291 cds-NP_015394.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:675161-676042:- gene-YPR069C_MUCL30387 rna-NM_001184166.1_MUCL30387 cds-NP_015394.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:673866-674747:- gene-YPR069C_MUCL30388 rna-NM_001184166.1_MUCL30388 cds-NP_015394.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:653179-654060:- gene-YPR069C_MUCL39482 rna-NM_001184166.1_MUCL39482 cds-NP_015394.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:716002-716883:- gene-YPR069C_MUCL42920 rna-NM_001184166.1_MUCL42920 cds-NP_015394.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:684539-685420:- gene-YPR069C_NCIM3186 rna-NM_001184166.1_NCIM3186 cds-NP_015394.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:661107-661988:- gene-YPR069C_NCYC1407 rna-NM_001184166.1_NCYC1407 cds-NP_015394.1_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:667310-668191:- gene-YPR069C_PE2H3 rna-NM_001184166.1_PE2H3 cds-NP_015394.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:666958-667839:- gene-YPR069C_PE2H4 rna-NM_001184166.1_PE2H4 cds-NP_015394.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:684556-685437:- gene-YPR069C_S288C rna-NM_001184166.1_S288C cds-NP_015394.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000026.1:15253-16134:+ gene-YPR069C_SA1 rna-NM_001184166.1_SA1 cds-NP_015394.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:661840-662721:- gene-YPR069C_ThermosaccDry rna-NM_001184166.1_ThermosaccDry cds-NP_015394.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:677984-678865:- gene-YPR069C_VR1 rna-NM_001184166.1_VR1 cds-NP_015394.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:661063-661944:- gene-YPR069C_ZTW1 rna-NM_001184166.1_ZTW1 cds-NP_015394.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:661820-662701:- gene-YPR069C_Sparadoxus rna-NM_001184166.1_Sparadoxus cds-NP_015394.1_Sparadoxus 92.9 100.0 Verified 1 1 1 False True False False False

Additional files