Gene name: SPE2
Reference locus (S288C): YOL052C
Gene biotype: protein_coding
Description: S-adenosylmethionine decarboxylase; required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobically; Belongs to the eukaryotic AdoMetDC family
Top 10 interactors (score): SPE3 (0.998); SPE4 (0.996); SPE1 (0.996); SAM2 (0.967); SAM1 (0.952); LIA1 (0.785); MRI1 (0.715); ERP5 (0.711); DYS1 (0.706); ADE5,7 (0.686); MEU1 (0.685); ADE8 (0.683); TRP5 (0.676); STR3 (0.661); CAR1 (0.657); ADI1 (0.648); STR2 (0.643); CAR2 (0.638); TAF6 (0.632); MDE1 (0.624)
Homologues (species, bitscore): AMD1 (Homo sapiens, 171.4); Amd1 (Mus musculus, 174.1); amd1 (Danio rerio, 163.7); amd1 (Xenopus tropicalis, 156.8); SamDC (Drosophila melanogaster, 172.2); smd-1 (Caenorhabditis elegans, 153.7); AT5G15950 (Arabidopsis thaliana, 144.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:216742-217932:- | gene-YOL052C_AKU4011 | rna-NM_001183306.1_AKU4011 | cds-NP_014590.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:32400-33590:- | gene-YOL052C_BG1 | rna-NM_001183306.1_BG1 | cds-NP_014590.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:219636-220826:- | gene-YOL052C_Bruggeman | rna-NM_001183306.1_Bruggeman | cds-NP_014590.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:217574-218764:- | gene-YOL052C_CAT1 | rna-NM_001183306.1_CAT1 | cds-NP_014590.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:211409-212599:- | gene-YOL052C_CBS1585 | rna-NM_001183306.1_CBS1585 | cds-NP_014590.1_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:215726-216916:- | gene-YOL052C_CBS436 | rna-NM_001183306.1_CBS436 | cds-NP_014590.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:210806-211996:- | gene-YOL052C_CBS6412 | rna-NM_001183306.1_CBS6412 | cds-NP_014590.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:218310-219500:- | gene-YOL052C_CBS6413 | rna-NM_001183306.1_CBS6413 | cds-NP_014590.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:232149-233339:- | gene-YOL052C_CENPK1137D | rna-NM_001183306.1_CENPK1137D | cds-NP_014590.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:213766-214956:- | gene-YOL052C_EthanolRed | rna-NM_001183306.1_EthanolRed | cds-NP_014590.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:216682-217872:- | gene-YOL052C_FaliES1 | rna-NM_001183306.1_FaliES1 | cds-NP_014590.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000018.1:48586-49776:+ | gene-YOL052C_JAY291 | rna-NM_001183306.1_JAY291 | cds-NP_014590.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:222407-223597:- | gene-YOL052C_MUCL30387 | rna-NM_001183306.1_MUCL30387 | cds-NP_014590.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:227006-228196:- | gene-YOL052C_MUCL30388 | rna-NM_001183306.1_MUCL30388 | cds-NP_014590.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:218927-220117:- | gene-YOL052C_MUCL39482 | rna-NM_001183306.1_MUCL39482 | cds-NP_014590.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:233909-235099:- | gene-YOL052C_MUCL42920 | rna-NM_001183306.1_MUCL42920 | cds-NP_014590.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:232335-233525:- | gene-YOL052C_NCIM3186 | rna-NM_001183306.1_NCIM3186 | cds-NP_014590.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:225671-226861:- | gene-YOL052C_NCYC1407 | rna-NM_001183306.1_NCYC1407 | cds-NP_014590.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:208094-209284:- | gene-YOL052C_PE2H3 | rna-NM_001183306.1_PE2H3 | cds-NP_014590.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:219068-220258:- | gene-YOL052C_PE2H4 | rna-NM_001183306.1_PE2H4 | cds-NP_014590.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:232446-233636:- | gene-YOL052C_S288C | rna-NM_001183306.1_S288C | cds-NP_014590.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:200416-201606:- | gene-YOL052C_SA1 | rna-NM_001183306.1_SA1 | cds-NP_014590.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:215253-216443:- | gene-YOL052C_ThermosaccDry | rna-NM_001183306.1_ThermosaccDry | cds-NP_014590.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:215317-216507:- | gene-YOL052C_VR1 | rna-NM_001183306.1_VR1 | cds-NP_014590.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:215128-216318:- | gene-YOL052C_ZTW1 | rna-NM_001183306.1_ZTW1 | cds-NP_014590.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:223468-224658:- | gene-YOL052C_Sparadoxus | rna-NM_001183306.1_Sparadoxus | cds-NP_014590.1_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |