Gene name: SPE1
Reference locus (S288C): YKL184W
Gene biotype: protein_coding
Description: Ornithine decarboxylase; catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines; deletion decreases lifespan, and increases necrotic cell death and ROS generation; Belongs to the Orn/Lys/Arg decarboxylase class-II family
Top 10 interactors (score): SPE3 (0.999); CAR1 (0.996); SPE2 (0.996); CAR2 (0.989); SPE4 (0.969); FMS1 (0.962); ARG5,6 (0.941); OAZ1 (0.912); DYS1 (0.899); SAL1 (0.874); ARG1 (0.863); CDC39 (0.833); ARG4 (0.825); HIS4 (0.764); ORT1 (0.762); TRP3 (0.76); NIT3 (0.755); MEU1 (0.743); HOM2 (0.741); UGA1 (0.72)
Homologues (species, bitscore): ODC1 (Homo sapiens, 333.6); Odc1 (Mus musculus, 334.0); odc1 (Danio rerio, 334.7); odc1 (Xenopus tropicalis, 333.2); Odc1 (Drosophila melanogaster, 264.2); odc-1 (Caenorhabditis elegans, 288.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:83614-85014:+ | gene-YKL184W_AKU4011 | rna-NM_001179750.1_AKU4011 | cds-NP_012737.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:60140-61540:+ | gene-YKL184W_BG1 | rna-NM_001179750.1_BG1 | cds-NP_012737.1_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:101002-102402:+ | gene-YKL184W_Bruggeman | rna-NM_001179750.1_Bruggeman | cds-NP_012737.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:95959-97359:+ | gene-YKL184W_CAT1 | rna-NM_001179750.1_CAT1 | cds-NP_012737.1_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:95596-96996:+ | gene-YKL184W_CBS1585 | rna-NM_001179750.1_CBS1585 | cds-NP_012737.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:94355-95755:+ | gene-YKL184W_CBS436 | rna-NM_001179750.1_CBS436 | cds-NP_012737.1_CBS436 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:81186-82586:+ | gene-YKL184W_CBS6412 | rna-NM_001179750.1_CBS6412 | cds-NP_012737.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:96314-97714:+ | gene-YKL184W_CBS6413 | rna-NM_001179750.1_CBS6413 | cds-NP_012737.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:96583-97983:+ | gene-YKL184W_CENPK1137D | rna-NM_001179750.1_CENPK1137D | cds-NP_012737.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:94500-95900:+ | gene-YKL184W_EthanolRed | rna-NM_001179750.1_EthanolRed | cds-NP_012737.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:95201-96601:+ | gene-YKL184W_FaliES1 | rna-NM_001179750.1_FaliES1 | cds-NP_012737.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:94184-95584:+ | gene-YKL184W_JAY291 | rna-NM_001179750.1_JAY291 | cds-NP_012737.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:103301-104701:+ | gene-YKL184W_MUCL30387 | rna-NM_001179750.1_MUCL30387 | cds-NP_012737.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:97646-99046:+ | gene-YKL184W_MUCL30388 | rna-NM_001179750.1_MUCL30388 | cds-NP_012737.1_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:95653-97053:+ | gene-YKL184W_MUCL39482 | rna-NM_001179750.1_MUCL39482 | cds-NP_012737.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:99984-101384:+ | gene-YKL184W_MUCL42920 | rna-NM_001179750.1_MUCL42920 | cds-NP_012737.1_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:96746-98146:+ | gene-YKL184W_NCIM3186 | rna-NM_001179750.1_NCIM3186 | cds-NP_012737.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:95677-97077:+ | gene-YKL184W_NCYC1407 | rna-NM_001179750.1_NCYC1407 | cds-NP_012737.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:102727-104127:+ | gene-YKL184W_PE2H3 | rna-NM_001179750.1_PE2H3 | cds-NP_012737.1_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:99021-100421:+ | gene-YKL184W_PE2H4 | rna-NM_001179750.1_PE2H4 | cds-NP_012737.1_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:96757-98157:+ | gene-YKL184W_S288C | rna-NM_001179750.1_S288C | cds-NP_012737.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:12958-14358:+ | gene-YKL184W_SA1 | rna-NM_001179750.1_SA1 | cds-NP_012737.1_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:95901-97301:+ | gene-YKL184W_ThermosaccDry | rna-NM_001179750.1_ThermosaccDry | cds-NP_012737.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:94432-95832:+ | gene-YKL184W_VR1 | rna-NM_001179750.1_VR1 | cds-NP_012737.1_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:94303-95703:+ | gene-YKL184W_ZTW1 | rna-NM_001179750.1_ZTW1 | cds-NP_012737.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:108901-110301:+ | gene-YKL184W_Sparadoxus | rna-NM_001179750.1_Sparadoxus | cds-NP_012737.1_Sparadoxus | 87.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |