Gene name: SPC3
Reference locus (S288C): YLR066W
Gene biotype: protein_coding
Description: Subunit of signal peptidase complex; complex catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC22/23; other members of the complex are Spc1p, Spc2p, and Sec11p
Top 10 interactors (score): SPC1 (0.999); SEC11 (0.999); SPC2 (0.996); OST2 (0.924); SSS1 (0.923); PRE8 (0.92); SEC65 (0.882); ERV29 (0.878); SWP1 (0.835); GPN2 (0.832); CCT2 (0.815); SEC20 (0.808); KAR2 (0.797); SPC25 (0.788); KRS1 (0.77); CCT7 (0.765); ERD2 (0.756); TTI1 (0.739); TSC13 (0.725); YJL009W (0.715)
Homologues (species, bitscore): SPCS3 (Homo sapiens, 75.1); Spcs3 (Mus musculus, 75.1); spcs3 (Danio rerio, 84.0); spcs3 (Xenopus tropicalis, 77.8); Spase22-23 (Drosophila melanogaster, 94.7); K12H4.4 (Caenorhabditis elegans, 70.9); AT3G05230 (Arabidopsis thaliana, 72.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:249641-250195:+ | gene-YLR066W_AKU4011 | rna-NM_001181953.1_AKU4011 | cds-NP_013167.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:212782-213336:+ | gene-YLR066W_BG1 | rna-NM_001181953.1_BG1 | cds-NP_013167.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:259550-260104:+ | gene-YLR066W_Bruggeman | rna-NM_001181953.1_Bruggeman | cds-NP_013167.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:259867-260421:+ | gene-YLR066W_CAT1 | rna-NM_001181953.1_CAT1 | cds-NP_013167.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:256757-257311:+ | gene-YLR066W_CBS1585 | rna-NM_001181953.1_CBS1585 | cds-NP_013167.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:247379-247933:+ | gene-YLR066W_CBS436 | rna-NM_001181953.1_CBS436 | cds-NP_013167.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:255195-255749:+ | gene-YLR066W_CBS6412 | rna-NM_001181953.1_CBS6412 | cds-NP_013167.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:257028-257582:+ | gene-YLR066W_CBS6413 | rna-NM_001181953.1_CBS6413 | cds-NP_013167.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:252191-252745:+ | gene-YLR066W_CENPK1137D | rna-NM_001181953.1_CENPK1137D | cds-NP_013167.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:249162-249716:+ | gene-YLR066W_EthanolRed | rna-NM_001181953.1_EthanolRed | cds-NP_013167.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:249038-249592:+ | gene-YLR066W_FaliES1 | rna-NM_001181953.1_FaliES1 | cds-NP_013167.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000129.1:23973-24527:+ | gene-YLR066W_JAY291 | rna-NM_001181953.1_JAY291 | cds-NP_013167.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:256919-257473:+ | gene-YLR066W_MUCL30387 | rna-NM_001181953.1_MUCL30387 | cds-NP_013167.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:264562-265116:+ | gene-YLR066W_MUCL30388 | rna-NM_001181953.1_MUCL30388 | cds-NP_013167.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:257268-257822:+ | gene-YLR066W_MUCL39482 | rna-NM_001181953.1_MUCL39482 | cds-NP_013167.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:257189-257743:+ | gene-YLR066W_MUCL42920 | rna-NM_001181953.1_MUCL42920 | cds-NP_013167.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:267143-267697:+ | gene-YLR066W_NCIM3186 | rna-NM_001181953.1_NCIM3186 | cds-NP_013167.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:249343-249897:+ | gene-YLR066W_NCYC1407 | rna-NM_001181953.1_NCYC1407 | cds-NP_013167.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:255210-255764:+ | gene-YLR066W_PE2H3 | rna-NM_001181953.1_PE2H3 | cds-NP_013167.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:254951-255505:+ | gene-YLR066W_PE2H4 | rna-NM_001181953.1_PE2H4 | cds-NP_013167.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:267169-267723:+ | gene-YLR066W_S288C | rna-NM_001181953.1_S288C | cds-NP_013167.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000033.1:106467-107021:- | gene-YLR066W_SA1 | rna-NM_001181953.1_SA1 | cds-NP_013167.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:249214-249768:+ | gene-YLR066W_ThermosaccDry | rna-NM_001181953.1_ThermosaccDry | cds-NP_013167.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:262903-263457:+ | gene-YLR066W_VR1 | rna-NM_001181953.1_VR1 | cds-NP_013167.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:248601-249155:+ | gene-YLR066W_ZTW1 | rna-NM_001181953.1_ZTW1 | cds-NP_013167.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:257480-258034:+ | gene-YLR066W_Sparadoxus | rna-NM_001181953.1_Sparadoxus | cds-NP_013167.1_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |