SPC25 (YER018C)


Gene profile

Gene name: SPC25
Reference locus (S288C): YER018C
Gene biotype: protein_coding

Description: Kinetochore protein SPC25; Component of the kinetochore-associated Ndc80 complex; involved in chromosome segregation, spindle checkpoint activity, and kinetochore clustering; evolutionarily conserved; other members include Ndc80p, Nuf2p, Spc24p, and Spc25p

Top 10 interactors (score): SPC24 (0.999); NUF2 (0.999); NDC80 (0.999); DSN1 (0.995); MTW1 (0.986); SPC105 (0.977); CNN1 (0.975); MAD2 (0.974); NSL1 (0.961); IPL1 (0.948); BUB1 (0.934); MPS1 (0.928); KAR3 (0.922); KIP1 (0.914); MAD3 (0.913); ASE1 (0.907); UBC11 (0.905); YCG1 (0.904); SMC2 (0.899); CDC45 (0.896)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:185993-186658:- gene-YER018C_AKU4011 rna-NM_001178909.3_AKU4011 cds-NP_010934.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:239433-240098:+ gene-YER018C_BG1 rna-NM_001178909.3_BG1 cds-NP_010934.3_BG1 99.6 100.0 Mismatch 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:193850-194515:- gene-YER018C_Bruggeman rna-NM_001178909.3_Bruggeman cds-NP_010934.3_Bruggeman 99.5 100.0 Mismatch 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:188740-189405:- gene-YER018C_CAT1 rna-NM_001178909.3_CAT1 cds-NP_010934.3_CAT1 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:185916-186581:- gene-YER018C_CBS1585 rna-NM_001178909.3_CBS1585 cds-NP_010934.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:187502-188167:- gene-YER018C_CBS436 rna-NM_001178909.3_CBS436 cds-NP_010934.3_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:186160-186825:- gene-YER018C_CBS6412 rna-NM_001178909.3_CBS6412 cds-NP_010934.3_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:190946-191611:- gene-YER018C_CBS6413 rna-NM_001178909.3_CBS6413 cds-NP_010934.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:189848-190513:- gene-YER018C_CENPK1137D rna-NM_001178909.3_CENPK1137D cds-NP_010934.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:186619-187284:- gene-YER018C_EthanolRed rna-NM_001178909.3_EthanolRed cds-NP_010934.3_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:186879-187544:- gene-YER018C_FaliES1 rna-NM_001178909.3_FaliES1 cds-NP_010934.3_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000024.1:53502-54167:- gene-YER018C_JAY291 rna-NM_001178909.3_JAY291 cds-NP_010934.3_JAY291 99.6 100.0 Mismatch 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:190042-190707:- gene-YER018C_MUCL30387 rna-NM_001178909.3_MUCL30387 cds-NP_010934.3_MUCL30387 99.6 100.0 Mismatch 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:186318-186983:- gene-YER018C_MUCL30388 rna-NM_001178909.3_MUCL30388 cds-NP_010934.3_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:184959-185624:- gene-YER018C_MUCL39482 rna-NM_001178909.3_MUCL39482 cds-NP_010934.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:191074-191739:- gene-YER018C_MUCL42920 rna-NM_001178909.3_MUCL42920 cds-NP_010934.3_MUCL42920 99.8 100.0 Mismatch 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:191958-192623:- gene-YER018C_NCIM3186 rna-NM_001178909.3_NCIM3186 cds-NP_010934.3_NCIM3186 99.5 100.0 Mismatch 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:190031-190696:- gene-YER018C_NCYC1407 rna-NM_001178909.3_NCYC1407 cds-NP_010934.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:194344-195009:- gene-YER018C_PE2H3 rna-NM_001178909.3_PE2H3 cds-NP_010934.3_PE2H3 99.6 100.0 Mismatch 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:190243-190908:- gene-YER018C_PE2H4 rna-NM_001178909.3_PE2H4 cds-NP_010934.3_PE2H4 99.6 100.0 Mismatch 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:191959-192624:- gene-YER018C_S288C rna-NM_001178909.3_S288C cds-NP_010934.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:51060-51725:+ gene-YER018C_SA1 rna-NM_001178909.3_SA1 cds-NP_010934.3_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:187650-188315:- gene-YER018C_ThermosaccDry rna-NM_001178909.3_ThermosaccDry cds-NP_010934.3_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:186403-187068:- gene-YER018C_VR1 rna-NM_001178909.3_VR1 cds-NP_010934.3_VR1 99.6 100.0 Mismatch 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:184862-185527:- gene-YER018C_ZTW1 rna-NM_001178909.3_ZTW1 cds-NP_010934.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:188628-189293:- gene-YER018C_Sparadoxus rna-NM_001178909.3_Sparadoxus cds-NP_010934.3_Sparadoxus 88.5 98.9 Verified 1 1 1 False True False False False

Additional files