Gene name: SPC110
Reference locus (S288C): YDR356W
Gene biotype: protein_coding
Description: Inner plaque spindle pole body (SPB) component; ortholog of human kendrin; gamma-tubulin small complex (gamma-TuSC) receptor that interacts with Spc98p to recruit the complex to the nuclear side of the SPB, connecting nuclear microtubules to the SPB; promotes gamma-TuSC assembly and oligomerization to initiate microtubule nucleation; interacts with Tub4p-complex and calmodulin; phosphorylated by Mps1p in cell cycle-dependent manner
Top 10 interactors (score): CMD1 (0.999); SPC42 (0.997); SPC97 (0.995); TUB4 (0.995); SPC98 (0.993); SPC29 (0.983); CNM67 (0.972); SPC72 (0.965); MPS1 (0.901); CDC28 (0.883); STU2 (0.881); MPS2 (0.874); CDC31 (0.868); BBP1 (0.864); SFI1 (0.858); MLP2 (0.853); SPC24 (0.799); MPS3 (0.799); KAR1 (0.783); POM152 (0.78)
Homologues (species, bitscore): LAMA3 (Homo sapiens, 75.1); Lama2 (Mus musculus, 75.1); lama5 (Danio rerio, 67.4); lama5 (Xenopus tropicalis, 67.4); epi-1 (Caenorhabditis elegans, 77.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1132172-1135006:+ | gene-YDR356W_AKU4011 | rna-NM_001180664.3_AKU4011 | cds-NP_010643.3_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:10720-13554:+ | gene-YDR356W_BG1 | rna-NM_001180664.3_BG1 | cds-NP_010643.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1162825-1165659:+ | gene-YDR356W_Bruggeman | rna-NM_001180664.3_Bruggeman | cds-NP_010643.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1141414-1144248:+ | gene-YDR356W_CAT1 | rna-NM_001180664.3_CAT1 | cds-NP_010643.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1126889-1129723:+ | gene-YDR356W_CBS1585 | rna-NM_001180664.3_CBS1585 | cds-NP_010643.3_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1145470-1148304:+ | gene-YDR356W_CBS436 | rna-NM_001180664.3_CBS436 | cds-NP_010643.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1123149-1125983:+ | gene-YDR356W_CBS6412 | rna-NM_001180664.3_CBS6412 | cds-NP_010643.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1145039-1147873:+ | gene-YDR356W_CBS6413 | rna-NM_001180664.3_CBS6413 | cds-NP_010643.3_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1184753-1187587:+ | gene-YDR356W_CENPK1137D | rna-NM_001180664.3_CENPK1137D | cds-NP_010643.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1136574-1139408:+ | gene-YDR356W_EthanolRed | rna-NM_001180664.3_EthanolRed | cds-NP_010643.3_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1139857-1142691:+ | gene-YDR356W_FaliES1 | rna-NM_001180664.3_FaliES1 | cds-NP_010643.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000057.1:48382-51215:- | gene-YDR356W_JAY291 | rna-NM_001180664.3_JAY291 | cds-NP_010643.3_JAY291 | 99.7 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1146122-1148956:+ | gene-YDR356W_MUCL30387 | rna-NM_001180664.3_MUCL30387 | cds-NP_010643.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1128729-1131563:+ | gene-YDR356W_MUCL30388 | rna-NM_001180664.3_MUCL30388 | cds-NP_010643.3_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1118423-1121257:+ | gene-YDR356W_MUCL39482 | rna-NM_001180664.3_MUCL39482 | cds-NP_010643.3_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1060356-1063190:+ | gene-YDR356W_MUCL42920 | rna-NM_001180664.3_MUCL42920 | cds-NP_010643.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1186030-1188864:+ | gene-YDR356W_NCIM3186 | rna-NM_001180664.3_NCIM3186 | cds-NP_010643.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1132096-1134930:+ | gene-YDR356W_NCYC1407 | rna-NM_001180664.3_NCYC1407 | cds-NP_010643.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1142523-1145357:+ | gene-YDR356W_PE2H3 | rna-NM_001180664.3_PE2H3 | cds-NP_010643.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1148108-1150942:+ | gene-YDR356W_PE2H4 | rna-NM_001180664.3_PE2H4 | cds-NP_010643.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1186107-1188941:+ | gene-YDR356W_S288C | rna-NM_001180664.3_S288C | cds-NP_010643.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000072.1:10801-13635:+ | gene-YDR356W_SA1 | rna-NM_001180664.3_SA1 | cds-NP_010643.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1144138-1146972:+ | gene-YDR356W_ThermosaccDry | rna-NM_001180664.3_ThermosaccDry | cds-NP_010643.3_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:571487-574321:+ | gene-YDR356W_VR1 | rna-NM_001180664.3_VR1 | cds-NP_010643.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:186972-189806:+ | gene-YDR356W_ZTW1 | rna-NM_001180664.3_ZTW1 | cds-NP_010643.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1138059-1140893:+ | gene-YDR356W_Sparadoxus | rna-NM_001180664.3_Sparadoxus | cds-NP_010643.3_Sparadoxus | 88.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |