Gene name: SPC1
Reference locus (S288C): YJR010C-A
Gene biotype: protein_coding
Description: Subunit of the signal peptidase complex (SPC); SPC cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER); homolog of the SPC12 subunit of mammalian signal peptidase complex; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): SPC3 (0.999); SEC11 (0.999); SPC2 (0.998); SBH2 (0.907); OST2 (0.901); ERV25 (0.896); TMA7 (0.896); EMC6 (0.886); SBH1 (0.885); SEC62 (0.882); SRP14 (0.828); SRP54 (0.795); SPC25 (0.788); SEC65 (0.75); YJL009W (0.744); SSS1 (0.739); SEC63 (0.703); YPF1 (0.694); ERV46 (0.691); RPB10 (0.691)
Homologues (species, bitscore): AT2G22425 (Arabidopsis thaliana, 52.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:441230-441514:- | gene-YJR010C-A_AKU4011 | rna-NM_001181667.1_AKU4011 | cds-NP_012544.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:171221-171505:+ | gene-YJR010C-A_BG1 | rna-NM_001181667.1_BG1 | cds-NP_012544.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:455323-455607:- | gene-YJR010C-A_Bruggeman | rna-NM_001181667.1_Bruggeman | cds-NP_012544.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:459259-459543:- | gene-YJR010C-A_CAT1 | rna-NM_001181667.1_CAT1 | cds-NP_012544.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:452819-453103:- | gene-YJR010C-A_CBS1585 | rna-NM_001181667.1_CBS1585 | cds-NP_012544.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:471790-472074:- | gene-YJR010C-A_CBS436 | rna-NM_001181667.1_CBS436 | cds-NP_012544.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:441050-441334:- | gene-YJR010C-A_CBS6412 | rna-NM_001181667.1_CBS6412 | cds-NP_012544.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:443273-443557:- | gene-YJR010C-A_CBS6413 | rna-NM_001181667.1_CBS6413 | cds-NP_012544.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:440562-440846:- | gene-YJR010C-A_CENPK1137D | rna-NM_001181667.1_CENPK1137D | cds-NP_012544.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:446213-446497:- | gene-YJR010C-A_EthanolRed | rna-NM_001181667.1_EthanolRed | cds-NP_012544.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:457429-457713:- | gene-YJR010C-A_FaliES1 | rna-NM_001181667.1_FaliES1 | cds-NP_012544.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000384.1:3667-3951:- | gene-YJR010C-A_JAY291 | rna-NM_001181667.1_JAY291 | cds-NP_012544.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:455639-455923:- | gene-YJR010C-A_MUCL30387 | rna-NM_001181667.1_MUCL30387 | cds-NP_012544.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:452173-452457:- | gene-YJR010C-A_MUCL30388 | rna-NM_001181667.1_MUCL30388 | cds-NP_012544.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:446273-446557:- | gene-YJR010C-A_MUCL39482 | rna-NM_001181667.1_MUCL39482 | cds-NP_012544.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:451585-451869:- | gene-YJR010C-A_MUCL42920 | rna-NM_001181667.1_MUCL42920 | cds-NP_012544.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:458056-458340:- | gene-YJR010C-A_NCIM3186 | rna-NM_001181667.1_NCIM3186 | cds-NP_012544.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:444130-444414:- | gene-YJR010C-A_NCYC1407 | rna-NM_001181667.1_NCYC1407 | cds-NP_012544.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:462444-462728:- | gene-YJR010C-A_PE2H3 | rna-NM_001181667.1_PE2H3 | cds-NP_012544.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:456138-456422:- | gene-YJR010C-A_PE2H4 | rna-NM_001181667.1_PE2H4 | cds-NP_012544.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:458077-458361:- | gene-YJR010C-A_S288C | rna-NM_001181667.1_S288C | cds-NP_012544.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:254070-254354:- | gene-YJR010C-A_SA1 | rna-NM_001181667.1_SA1 | cds-NP_012544.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:451079-451363:- | gene-YJR010C-A_ThermosaccDry | rna-NM_001181667.1_ThermosaccDry | cds-NP_012544.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:453363-453647:- | gene-YJR010C-A_VR1 | rna-NM_001181667.1_VR1 | cds-NP_012544.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:431008-431292:- | gene-YJR010C-A_ZTW1 | rna-NM_001181667.1_ZTW1 | cds-NP_012544.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:455897-456181:- | gene-YJR010C-A_Sparadoxus | rna-NM_001181667.1_Sparadoxus | cds-NP_012544.1_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |