Gene name: SPB4
Reference locus (S288C): YFL002C
Gene biotype: protein_coding
Description: Putative ATP-dependent RNA helicase; nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway; sediments with 66S pre-ribosomes in sucrose gradients; Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily
Top 10 interactors (score): YTM1 (0.999); ERB1 (0.999); RRP5 (0.997); RPF2 (0.997); ECM16 (0.997); NOP7 (0.997); NOC2 (0.996); NIP7 (0.996); NOP2 (0.996); NOG1 (0.995); CBF5 (0.995); DBP8 (0.995); NOP15 (0.995); KRR1 (0.994); KRE33 (0.994); PWP2 (0.994); RLP24 (0.994); NOP58 (0.994); ROK1 (0.994); NOP56 (0.993)
Homologues (species, bitscore): DDX55 (Homo sapiens, 362.8); Ddx55 (Mus musculus, 366.7); ddx55 (Danio rerio, 345.1); ddx55 (Xenopus tropicalis, 352.8); CG9630 (Drosophila melanogaster, 321.2); ZK512.2 (Caenorhabditis elegans, 265.0); AT1G71370 (Arabidopsis thaliana, 331.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:135560-137380:- | gene-YFL002C_AKU4011 | rna-NM_001179964.1_AKU4011 | cds-NP_116654.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000079.1:20454-22274:- | gene-YFL002C_BG1 | rna-NM_001179964.1_BG1 | cds-NP_116654.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:135126-136946:- | gene-YFL002C_Bruggeman | rna-NM_001179964.1_Bruggeman | cds-NP_116654.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:140288-142108:- | gene-YFL002C_CAT1 | rna-NM_001179964.1_CAT1 | cds-NP_116654.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:136385-138205:- | gene-YFL002C_CBS1585 | rna-NM_001179964.1_CBS1585 | cds-NP_116654.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:110231-112051:- | gene-YFL002C_CBS436 | rna-NM_001179964.1_CBS436 | cds-NP_116654.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:136126-137946:- | gene-YFL002C_CBS6412 | rna-NM_001179964.1_CBS6412 | cds-NP_116654.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:138636-140456:- | gene-YFL002C_CBS6413 | rna-NM_001179964.1_CBS6413 | cds-NP_116654.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:141246-143066:- | gene-YFL002C_CENPK1137D | rna-NM_001179964.1_CENPK1137D | cds-NP_116654.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:134546-136366:- | gene-YFL002C_EthanolRed | rna-NM_001179964.1_EthanolRed | cds-NP_116654.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:136193-138013:- | gene-YFL002C_FaliES1 | rna-NM_001179964.1_FaliES1 | cds-NP_116654.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000451.1:298-2118:- | gene-YFL002C_JAY291 | rna-NM_001179964.1_JAY291 | cds-NP_116654.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:136757-138577:- | gene-YFL002C_MUCL30387 | rna-NM_001179964.1_MUCL30387 | cds-NP_116654.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:134734-136554:- | gene-YFL002C_MUCL30388 | rna-NM_001179964.1_MUCL30388 | cds-NP_116654.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:134829-136649:- | gene-YFL002C_MUCL39482 | rna-NM_001179964.1_MUCL39482 | cds-NP_116654.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:134093-135913:- | gene-YFL002C_MUCL42920 | rna-NM_001179964.1_MUCL42920 | cds-NP_116654.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:145113-146933:- | gene-YFL002C_NCIM3186 | rna-NM_001179964.1_NCIM3186 | cds-NP_116654.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:135844-137664:- | gene-YFL002C_NCYC1407 | rna-NM_001179964.1_NCYC1407 | cds-NP_116654.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:154908-156728:- | gene-YFL002C_PE2H3 | rna-NM_001179964.1_PE2H3 | cds-NP_116654.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:154456-156276:- | gene-YFL002C_PE2H4 | rna-NM_001179964.1_PE2H4 | cds-NP_116654.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:145114-146934:- | gene-YFL002C_S288C | rna-NM_001179964.1_S288C | cds-NP_116654.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:177293-179113:+ | gene-YFL002C_SA1 | rna-NM_001179964.1_SA1 | cds-NP_116654.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:135353-137173:- | gene-YFL002C_ThermosaccDry | rna-NM_001179964.1_ThermosaccDry | cds-NP_116654.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:150555-152375:- | gene-YFL002C_VR1 | rna-NM_001179964.1_VR1 | cds-NP_116654.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:65802-67622:- | gene-YFL002C_ZTW1 | rna-NM_001179964.1_ZTW1 | cds-NP_116654.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:158989-160809:- | gene-YFL002C_Sparadoxus | rna-NM_001179964.1_Sparadoxus | cds-NP_116654.1_Sparadoxus | 89.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |